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Cholinergic Receptor, Nicotinic, delta (Muscle) Proteins (CHRND)

The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. Additionally we are shipping Cholinergic Receptor, Nicotinic, delta (Muscle) Antibodies (43) and Cholinergic Receptor, Nicotinic, delta (Muscle) Kits (32) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CHRND 1144 Q07001
Rat CHRND CHRND 54240 P25110
CHRND 11447 P02716
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Top Cholinergic Receptor, Nicotinic, delta (Muscle) Proteins at antibodies-online.com

Showing 5 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

CHRND Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine) ,
,

More Proteins for Cholinergic Receptor, Nicotinic, delta (Muscle) (CHRND) Interaction Partners

Human Cholinergic Receptor, Nicotinic, delta (Muscle) (CHRND) interaction partners

  1. Data suggest mutation in invariant Cys-loop of CHRND (D140N) observed in muscle of one patient (11 y/o girl) with congenital myasthenia (w/ severe muscle weakness) alters conformation of ligand/acetylcholine binding site and receptor functionality.

  2. No mutations were found in CHRNG (show CHRNG Proteins), CHRND and CHRNA1 (show CHRNA1 Proteins) genes of Indian families with Escobar syndrome.

  3. No CHRNA1 (show CHRNA1 Proteins), CHRNB1 (show CHRNB1 Proteins), or CHRND mutations were detected, but a homozygous RAPSN (show RAPSN Proteins) frameshift mutation, c.1177-1178delAA, was identified in a family with three children affected with lethal fetal akinesia sequence.

  4. study reports homozygous nonsense mutations in CHRNA1 and CHRND and shows that they were lethal

  5. Results describe the effects of a point mutation in the AChR delta subunit from a congenital myasthenia patient.

Zebrafish Cholinergic Receptor, Nicotinic, delta (Muscle) (CHRND) interaction partners

  1. Mutation in the delta-subunit of nAChR (show CHRNA4 Proteins) suppresses the muscle defects caused by lack of dystrophin (show DMD Proteins).

  2. direct involvement of the AChR molecule in restricting receptor-rapsyn (show RAPSN Proteins) clusters to the synapse

  3. sop(-/-) mutants are able to support normal potassium current development during early stages of development but at day 6 the potassium current density is significantly smaller than that in wild-type siblings. sodium current density is unaffected

Mouse (Murine) Cholinergic Receptor, Nicotinic, delta (Muscle) (CHRND) interaction partners

  1. Bone marrow-derived mesenchymal stem cells up-regulate skeletal muscle acetylcholine receptor delta subunit through NRG/ErbB3 (show ERBB3 Proteins)-mediated mitogen-activated protein kinase (show MAPK1 Proteins) pathway.

  2. Delay in maturation of the nAChR (show CHRNA4 Proteins) clusters during the early postnatal synapse elimination period in protein kinase C (PKCtheta (show PRKCQ Proteins); deficient mice coincides with a reduction in PKCtheta (show PRKCQ Proteins);-mediated phosphorylation of the nAChR (show CHRNA4 Proteins) delta subunit.

Cholinergic Receptor, Nicotinic, delta (Muscle) (CHRND) Protein Profile

Protein Summary

The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Defects in this gene are a cause of multiple pterygium syndrome lethal type (MUPSL), congenital myasthenic syndrome slow-channel type (SCCMS), and congenital myasthenic syndrome fast-channel type (FCCMS). Several transcript variants, some protein-coding and some not, have been found for this gene.

Gene names and symbols associated with CHRND

  • cholinergic receptor, nicotinic, delta (CHRND)
  • cholinergic receptor, nicotinic, delta (muscle) (CHRND)
  • cholinergic receptor, nicotinic, delta (muscle) (Chrnd)
  • cholinergic receptor, nicotinic, delta (muscle) (chrnd)
  • cholinergic receptor, nicotinic, delta polypeptide (chrnd)
  • cholinergic receptor, nicotinic, delta polypeptide (Chrnd)
  • Achr-4 protein
  • ACHRD protein
  • Acrd protein
  • chnrd protein
  • chrng protein
  • CMS2A protein
  • FCCMS protein
  • L10076 protein
  • SCCMS protein
  • wu:fa01e01 protein
  • zgc:110469 protein

Protein level used designations for CHRND

acetylcholine receptor subunit delta , cholinergic receptor, nicotinic, delta polypeptide , acetylcholine receptor, nicotinic, delta (muscle) , acetylcholine receptor delta subunit precursor (AA -21 to 500) , acetylcholine receptor delta subunit , sofa potato , sop , AChR delta subunit

GENE ID SPECIES
281687 Bos taurus
424940 Gallus gallus
1144 Homo sapiens
486162 Canis lupus familiaris
54240 Rattus norvegicus
100522042 Sus scrofa
444847 Xenopus laevis
101102707 Ovis aries
404273 Danio rerio
11447 Mus musculus
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