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Chondroitin Sulfate Synthase 1 (CHSY1) ELISA Kits

CHSY1 encodes a member of the chondroitin N-acetylgalactosaminyltransferase family. Additionally we are shipping Chondroitin Sulfate Synthase 1 Antibodies (36) and Chondroitin Sulfate Synthase 1 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat CHSY1 CHSY1 292999  
Anti-Human CHSY1 CHSY1 22856 Q86X52
Anti-Mouse CHSY1 CHSY1 269941 Q6ZQ11
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More ELISA Kits for Chondroitin Sulfate Synthase 1 Interaction Partners

Human Chondroitin Sulfate Synthase 1 (CHSY1) interaction partners

  1. CHSY1 expression is closely associated with malignant potential of soft tissue sarcomas with myxoid substance.

  2. A novel missense mutation (c.1897 G > A) in the CHSY1 gene in two Temtamy preaxial brachydactyly syndrome patients from a consanguineous Pakistani family.

  3. elongation of chondroitin sulfate chains may be tightly regulated by the cooperative expression of chondroitin synthase-1 and chondroitin N-acetylgalactosaminyltransferase-1 in peripheral neurons and peripheral neuropathies

  4. conclude that CHSY1 is a secreted FRINGE enzyme required for adjustment of NOTCH (show NOTCH1 ELISA Kits) signaling throughout human and fish embryogenesis and particularly during limb patterning

  5. unrestricted Bmp2b (show BMP4 ELISA Kits) signaling or loss of Dan activity leads to reduced chsy1 expression and, during epithelial morphogenesis, defects similar to those that occur upon Chsy1 inactivation

  6. chondroitin polymerizing activity requires concomitant expression of a ChPF with ChSy; coexpression of the ChPF and ChSy yielded markedly augmented glycosyltransferase activities, whereas simple mixing of the two separately expressed proteins did not.

Mouse (Murine) Chondroitin Sulfate Synthase 1 (CHSY1) interaction partners

  1. Data indicate a phosphorylated tetrasaccharide linkage structure, GlcUAbeta1-3Galbeta1-3Galbeta1-4Xyl(2-O-phosphate), in chondroitin N-acetylgalactosaminyltransferase-1 knockout ChGn-1(-/-) growth plate cartilage.

  2. The results showed that Chsy1 is an essential regulator of joint patterning and provide a mouse model of human brachydactylies caused by mutations in CHSY1.

Chondroitin Sulfate Synthase 1 (CHSY1) Antigen Profile

Antigen Summary

This gene encodes a member of the chondroitin N-acetylgalactosaminyltransferase family. These enzymes possess dual glucuronyltransferase and galactosaminyltransferase activity and play critical roles in the biosynthesis of chondroitin sulfate, a glycosaminoglycan involved in many biological processes including cell proliferation and morphogenesis. Decreased expression of this gene may play a role in colorectal cancer, and mutations in this gene are a cause of temtamy preaxial brachydactyly syndrome.

Gene names and symbols associated with CHSY1

  • chondroitin sulfate synthase 1 (Chsy1) antibody
  • chondroitin sulfate synthase 1 (CHSY1) antibody
  • CHSY antibody
  • ChSy-1 antibody
  • CSS1 antibody
  • mKIAA0990 antibody
  • TPBS antibody

Protein level used designations for CHSY1

carbohydrate (chondroitin) synthase 1 , N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1 , N-acetylgalactosaminyltransferase II , carbohydrate synthase 1 , chondroitin glucuronyltransferase 1 , chondroitin glucuronyltransferase II , chondroitin synthase 1 , glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1 , N-acetylgalactosaminyltransferase 1 , chSy-1

292999 Rattus norvegicus
22856 Homo sapiens
269941 Mus musculus
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