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Chordin-Like 1 Proteins (CHRDL1)

CHRDL1 encodes an antagonist of bone morphogenetic protein 4. Additionally we are shipping Chordin-Like 1 Antibodies (51) and Chordin-Like 1 Kits (9) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CHRDL1 83453 Q920C1
CHRDL1 91851 Q9BU40
Rat CHRDL1 CHRDL1 363455 Q76LD0
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Top Chordin-Like 1 Proteins at

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days

CHRDL1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,

More Proteins for Chordin-Like 1 (CHRDL1) Interaction Partners

Mouse (Murine) Chordin-Like 1 (CHRDL1) interaction partners

  1. CHRDL-1 is a new regulatory target of miR (show MLXIP Proteins)-134 during cortical neuronal differentiation; this is a novel role for miR (show MLXIP Proteins)-134 in the modulation of cortical development.

  2. Reperfusion injury of proximal kidney tubules causes a reduction of Chrdl1 expression.

Human Chordin-Like 1 (CHRDL1) interaction partners

  1. These studies have identified and validated new factors enriched in juvenile chondrocytes as compared to adult chondrocytes including secreted extracellular matrix factors chordin-like 1 (CHRDL1) and microfibrillar-associated protein 4 (MFAP4 (show MFAP4 Proteins)).

  2. We provide the initial confirmation that X-linked megalocornea is associated with mutations in the CHRDL1 gene.

  3. CHRDL1 plays a key role in cornea homeostasis as evidenced by disease causing mutations in X-linked megalocornea.

  4. The detection of mutations in the CHRDL1 gene is useful for differential diagnosis with different forms of megalocornea.

  5. Novel CHRDL1 mutations in ten families with X-linked megalocornea, are reported.

  6. CHRDL1 is expressed in the developing human cornea and anterior segment in addition to the retina.

  7. Hypoxia-induced upregulation of CHL-1 alters the homeostatic balance between BMP-4 and VEGF to synergize with VEGF in driving retinal angiogenesis.

  8. reports the cloning of chick ventroptin and its importance in topographic retinotectal projection

Chordin-Like 1 (CHRDL1) Protein Profile

Protein Summary

This gene encodes an antagonist of bone morphogenetic protein 4. The encoded protein may play a role in topographic retinotectal projection and in the regulation of retinal angiogenesis in response to hypoxia. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene names and symbols associated with Chordin-Like 1 Proteins (CHRDL1)

  • chordin-like 1 (CHRDL1)
  • chordin-like 1 (chrdl1)
  • chordin-like 1 (Chrdl1)
  • CHL protein
  • CHL1 protein
  • dA141H5.1 protein
  • Kjr protein
  • Neurogenesin-1 protein
  • Ng1 protein
  • NRLN1 protein
  • VOPT protein

Protein level used designations for Chordin-Like 1 Proteins (CHRDL1)

chordin-like 1 , chordin-like protein 1-like , chordin-like protein 1 , neuralin-1 , neurogenesin-1 , ventroptin-alpha , ventroptin-beta , neuralin 1 , ventroptin , kohjirin , neurogenesin 1 , likely ortholog of mouse neuralin 1

100059105 Equus caballus
100144642 Xenopus (Silurana) tropicalis
100435136 Pongo abelii
100481754 Ailuropoda melanoleuca
100591854 Nomascus leucogenys
83453 Mus musculus
91851 Homo sapiens
363455 Rattus norvegicus
373985 Gallus gallus
492066 Canis lupus familiaris
100521058 Sus scrofa
540275 Bos taurus
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