Chromobox Homolog 1 (CBX1) ELISA Kits

CBX1 encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . Additionally we are shipping Chromobox Homolog 1 Antibodies (96) and Chromobox Homolog 1 Proteins (8) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse CBX1 CBX1 12412 P83917
Anti-Human CBX1 CBX1 10951 P83916
Anti-Rat CBX1 CBX1 360609  
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More ELISA Kits for Chromobox Homolog 1 Interaction Partners

Mouse (Murine) Chromobox Homolog 1 (CBX1) interaction partners

  1. We demonstrate an unexpected duality in the role of HP1b: it is essential in ESCs (show NR2E3 ELISA Kits) for maintaining pluripotency, while it is required for proper differentiation in differentiated cells.

  2. The N-terminal portion of LBR (show LBR ELISA Kits) is probably responsible for the binding to HP1b.

  3. HP1b negatively regulates MMP2 (show MMP2 ELISA Kits) expression in a transcriptional level and prevents MMP2 (show MMP2 ELISA Kits) activation through reducing the expression of MT1MMP (show MMP14 ELISA Kits).

  4. Study concludes that only the 53BP1 (show TP53BP1 ELISA Kits) status in DNA lesions, induced by UVA or gamma-rays, is affected by A-type lamin (show LMNA ELISA Kits) deficiency, which was not observed for heterochromatin-related proteins HP1beta and BMI1 (show BMI1 ELISA Kits).

  5. SUV39h1 (show SUV39H1 ELISA Kits) associated with HP1 beta in fibrillarin (show FBL ELISA Kits)-positive nucleolar regions.

  6. demonstrate that a green fluorescent protein-HP1beta fusion protein is highly mobile within both the euchromatin and heterochromatin of ex vivo resting T cells; T cell activation greatly increased this mobility

  7. HP1 (show CBX5 ELISA Kits) isotypes have specific nonredundant functions; HP1 beta plays an essential role in the shuttling of corepressor transcriptional intermediary factor (TIF)1 (show TRIM24 ELISA Kits) beta from eu- to heterochromatin during cell differentiation in vivo.

  8. The localization, dynamics, and mobility of HP1beta in the in mouse preimplantation embryos (pro)nucleus were examined.

  9. HP1alpha (show CBX5 ELISA Kits) and HP1beta proteins on the heterochromatin of transcriptionally active oocytes and their absence in transcriptionally silent oocytes suggest that they are necessary for the repression of RNA synthesis in heterochromatin domains.

  10. HP1-beta is required for development of the cerebral neocortex and neuromuscular junctions

Human Chromobox Homolog 1 (CBX1) interaction partners

  1. the prolyl residue of the PXXVXL motif appears to play a role distinct from that of Pro in the known HP1beta CSD (show TGFBI ELISA Kits)-PXVXL complexes.

  2. Data show that heterochromatin protein 1-beta (HP1beta) is a prototypic HP1 (show DEFA1 ELISA Kits) protein exemplifying most basal chromatin binding and effects.

  3. increased HP1beta expression is associated with the poor prognosis in breast cancer

  4. In this review, we summarize the current knowledge about targeting and functional mechanisms of PRCs, emphasizing the recent breakthroughs related to CBX proteins under a number of physiological and pathological conditions.

  5. Data suggest the reduction of Heterochromatin Protein 1 isoforms HP1beta followed by a decrease in HP1alpha (show CBX5 ELISA Kits) contributes to the pathogenesis of thyroid carcinomas, and their loss is a potential marker of thyroid malignancy and metastatic potential, respectively.

  6. Phosphorylation at Ser89 and Ser175 results in localized conformational changes in HP1beta that do not compromise the ability of the protein to bind chromatin.

  7. HP1 (show DEFA1 ELISA Kits) isoforms distinctly augment AR signaling and cell growth in prostate cancer. Therefore, silencing of HP1beta and HP1gamma (show CBX3 ELISA Kits) may be a promising therapeutic strategy for treatment of prostate cancer.

  8. The structural plasticity of HP1beta supports its ability to bind and connect a wide variety of binding partners in epigenetic processes.

  9. HP1beta which is associated with PCNA (show PCNA ELISA Kits) in regions of DNA repair, is bound and does not exchange with the mobile pool, suggesting that HP1beta in association with PCNA (show PCNA ELISA Kits) may be a component of a DNA repair complex.

  10. The HP1beta interactome is enriched with Lys (show LYZ ELISA Kits) methylated proteins.Role of HP1beta in DNA damage response.

Chromobox Homolog 1 (CBX1) Antigen Profile

Antigen Summary

This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene names and symbols associated with Chromobox Homolog 1 (CBX1) ELISA Kits

  • chromobox 1 (Cbx1) antibody
  • chromobox homolog 1 (CBX1) antibody
  • chromobox homolog 1 (Cbx1) antibody
  • chromobox homolog 1 (cbx1) antibody
  • chromobox homolog 1a (HP1 beta homolog Drosophila) (cbx1a) antibody
  • CBX antibody
  • Cbx-rs2 antibody
  • cbx1 antibody
  • E430007M08Rik antibody
  • HP1-BETA antibody
  • HP1B antibody
  • Hp1beta antibody
  • HP1Hs-beta antibody
  • HP1Hsbeta antibody
  • M31 antibody
  • MOD1 antibody
  • p25beta antibody
  • wu:fe14b09 antibody
  • zgc:55739 antibody

Protein level used designations for Chromobox Homolog 1 (CBX1) ELISA Kits

HP1 beta , chromobox homolog 1 , chromobox protein homolog 1 , heterochromatin protein 1 homolog beta , heterochromatin protein p25 , modifier 1 protein , HP1 beta homolog , chromobox homolog 1 (HP1 beta homolog Drosophila ) , heterochromatin protein 1-beta , heterochromatin protein p25 beta , chromobox homolog 1 (HP1 beta homolog) , chromobox-like protein 1

12412 Mus musculus
10951 Homo sapiens
491051 Canis lupus familiaris
360609 Rattus norvegicus
444708 Xenopus laevis
374237 Gallus gallus
616506 Bos taurus
326746 Danio rerio
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