anti-Chromobox Homolog 2 (CBX2) Antibodies

CBX2 encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Additionally we are shipping CBX2 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CBX2 12416 P30658
CBX2 84733 Q14781
CBX2 303730  
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Top anti-CBX2 Antibodies at antibodies-online.com

Showing 10 out of 73 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-CBX2 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>Human heart 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-CBX2 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>OVCAR-3 cell lysate WB Suggested Anti-CBX2 <br /> Antibody Titration: 0.2-1 µg/mL <br /> Positive Control: OVCAR-3 cell lysate <br /> CBX2 is supported by BioGPS gene expression data to be expressed in OVCAR3 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of CBX2 Antibody (N-term) (ABIN653558) in MDA-MB231 cell line lysates (35 µg/lane). CBX2 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB <span>Western blot analysis of CBX2 Antibody (N-term) in MDA-MB231 cell line lysates (35µg/lane). CBX2 (arrow) was detected using the purified Pab.</span> 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Mouse Rabbit Un-conjugated ELISA 50 μL Log in to see 2 to 3 Days
$185.00
Details
Human Rabbit Un-conjugated WB CBX2 Antibody (Center)  western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the CBX2 antibody detected the CBX2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged CBX2 is approximately 3 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details

CBX2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) , , ,
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Human , , , ,
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Rat (Rattus)


More Antibodies against CBX2 Interaction Partners

Mouse (Murine) Chromobox Homolog 2 (CBX2) interaction partners

  1. the compaction region of CBX2 plays a key role in establishing proper axial patterning, thereby expanding the functional regions of this protein.

  2. We find that the N-terminus of Cbx2 is needed for its recruitment to mitotic chromosomes, whereas the C-terminus is required for its immobilization.

  3. Cbx2 targets PRC1 (show PRC1 Antibodies) to constitutive heterochromatin in mouse zygotes in a parent-of-origin-dependent manner.

  4. This study implicates Cbx2 in testis differentiation through regulating Sry (show SRY Antibodies) gene expression.

  5. Data show that Polycomb repressive complex 2 is necessary to maintain normal levels of OGT and for the correct cellular distribution of O-GlcNAc.

  6. Zfp277 in the transcriptional regulation of the Ink4a/Arf (show CDKN2A Antibodies) locus and the recruitment of PRC1 (show PRC1 Antibodies) to the Ink4a/Arf (show CDKN2A Antibodies) locus

  7. these results suggest that the binding specificity of Cbx2 protein for methylated histones is regulated by phosphorylation.

  8. murine geminin (show GMNN Antibodies) associates transiently with members of the Hox (show MSH2 Antibodies)-repressing polycomb complex, with the chromatin of Hox (show MSH2 Antibodies) regulatory DNA elements and with Hox (show MSH2 Antibodies) proteins

  9. Polycomb protein M33 controls critical expansion of B- and T-lymphocyte precursors

  10. The Polycomb M33 gene is an essential upstream regulator of Ad4BP/SF1 (show NR5A1 Antibodies).

Human Chromobox Homolog 2 (CBX2) interaction partners

  1. Data show that basal-like subgroup was enriched for aggressive tumors and somatic mutations in trithorax (show MLLT1 Antibodies)-group genes and it overexpressed polycomb genes EZH2 (show EZH2 Antibodies) and CBX2.

  2. CBX2 role in the sex development cascade is to stimulate the male pathway and concurrently inhibit the female pathway.

  3. CBX2 upregulation and amplification significantly correlated with metastatic progression and lower overall survival in many cancer types, particularly those of the breast

  4. This study does not support CBX2 gene disruption as a common cause of gonadal gonadal disorders of sex development.

  5. Two distinct mechanisms are involved in CBX2-mediated gene silencing. The short CBX2-2 isoform would repress the transcription in a PRC1 (show PRC1 Antibodies)-independent fashion, whereas gene repression by the long CBX2-1 isoform is mediated by the PRC1 (show PRC1 Antibodies) protein complex.

  6. CDYL (show CDYL Antibodies) functions as a molecular bridge between PRC2 and the repressive chromatin mark H3K27me3, forming a positive feedback loop to facilitate the establishment and propagation of H3K27me3 modifications along the chromatin

  7. hPc2 (show ELAC2 Antibodies) serves as a SUMO E3 ligase (show PIAS1 Antibodies) for cystathionine beta-synthase (show CBS Antibodies), increasing the efficiency of sumoylation.

CBX2 Antigen Profile

Protein Summary

This gene encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of this gene in mice results in male-to-female gonadal sex reversal. Mutations in this gene are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Gene names and symbols associated with CBX2

  • chromobox 2 (cbx2) antibody
  • chromobox 2 (CBX2) antibody
  • chromobox homolog 2 (Drosophila Pc class) (cbx2) antibody
  • chromobox 2 (Cbx2) antibody
  • chromobox 2 L homeolog (cbx2.L) antibody
  • cbx2 antibody
  • cdca6 antibody
  • m33 antibody
  • MOD2 antibody
  • pc antibody
  • pc1 antibody
  • SRXY5 antibody
  • wu:fd20e09 antibody
  • zgc:103563 antibody

Protein level used designations for CBX2

chromobox homolog 2 , modifier 3 protein , chromobox protein homolog 2-like , chromobox homolog 2 (Pc class homolog, Drosophila) , chromobox protein homolog 2 , M33 polycomb-like protein , hromobox homolog 2 , polycomb , Pc class homolog , cell division cycle associated 6 , modifier 3 , Polycomb homolog Pc1 , chromobox homolog 2 (Pc class homolog)

GENE ID SPECIES
100125497 Oryzias latipes
100410455 Callithrix jacchus
327291 Danio rerio
12416 Mus musculus
84733 Homo sapiens
398110 Xenopus laevis
426248 Gallus gallus
483349 Canis lupus familiaris
303730 Rattus norvegicus
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