Chromobox Homolog 8 (CBX8) ELISA Kits

Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. Additionally we are shipping CBX8 Antibodies (137) and CBX8 Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse CBX8 CBX8 30951 Q9QXV1
Anti-Human CBX8 CBX8 57332 Q9HC52
Anti-Rat CBX8 CBX8 303731  
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More ELISA Kits for CBX8 Interaction Partners

Mouse (Murine) Chromobox Homolog 8 (CBX8) interaction partners

  1. CBX8 plates roles in epigenetic regulation in DNA damage response.

  2. Cbx8 is upregulated and recruited to activated genes during embryonic stem cell differentiation.

  3. CBX8 plays an essential role in MLL (show MLL ELISA Kits)-AF9 (show MLLT3 ELISA Kits) transcriptional regulation and leukemogenesis.

  4. Pcl2-PRC2 facilitates both PRC2 recruitment to the inactive X chromosome in differentiating XX ES cells and PRC2 recruitment to target genes in undifferentiated ES cells.

  5. Huntingtin (show HTT ELISA Kits) is a novel stimulator of polycomb (show CBX2 ELISA Kits) repressive complex 2.

Human Chromobox Homolog 8 (CBX8) interaction partners

  1. CBX8 plates roles in epigenetic regulation in DNA damage response.

  2. IGF1 (show IGF1 ELISA Kits) can promote the colon cancer cell line, HCT116 cell, proliferation via promoting Cbx8 expression

  3. The difference in the SUZ12 (show SUZ12 ELISA Kits) and CBX8 genes expression were significantly divergent between tumors and their marginal tissues.

  4. These data suggest that CBX8 modulates SIPS through the RB-E2F1 pathway in CML cells and provide important insight into its application in CML treatment.

  5. Low CBX8 expression was associated with distant metastasis in colorectal cancer.

  6. CBX8 might emerge as an oncogene (show RAB1A ELISA Kits) for promoting the proliferation of tumor cells and raising the resistance of neoplasms to chemotherapy.

  7. The presence of CBX8-GFP in the same focus had a minor impact on BMI1 and RING1 recovery kinetics.

  8. Interaction with CBX8 precludes AF9 (show MLLT3 ELISA Kits)-DOT1L (show DOT1L ELISA Kits) binding.

  9. CBX8 cooperated with SIRT1 (show SIRT1 ELISA Kits) for suppressing p53 (show TP53 ELISA Kits) acetylation induced by Sirtinol and etoposide/TSA (show PRDX2 ELISA Kits). Upon ectopic expression, CBX8 or SIRT1 (show SIRT1 ELISA Kits) repressed the expression of p21(WAF1 (show CDKN1A ELISA Kits)) by inhibiting p53 (show TP53 ELISA Kits) binding to the promoter.

  10. CBX8 plays an essential role in MLL (show MLL ELISA Kits)-AF9 (show MLLT3 ELISA Kits) transcriptional regulation and leukemogenesis.

CBX8 Antigen Profile

Antigen Summary

Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones\; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

Gene names and symbols associated with Chromobox Homolog 8 (CBX8) ELISA Kits

  • chromobox homolog 8 (cbx8) antibody
  • chromobox homolog 8 (CBX8) antibody
  • chromobox 8 (Cbx8) antibody
  • chromobox homolog 8 (Cbx8) antibody
  • chromobox homolog 8a (Pc class homolog, Drosophila) (cbx8a) antibody
  • cbx8 antibody
  • MGC147589 antibody
  • PC3 antibody
  • RC1 antibody

Protein level used designations for Chromobox Homolog 8 (CBX8) ELISA Kits

chromobox homolog 8 , chromobox protein homolog 8 , mPc3 , polycomb 3 homolog , Pc class 3 homolog , chromobox homolog 8 (Pc class homolog, Drosophila) , polycomb 3 , rectachrome 1 , chromobox-like protein 8 , chromobox homolog 8 (Pc class homolog) , chromobox homolog 8a

GENE ID SPECIES
779897 Xenopus (Silurana) tropicalis
100604409 Nomascus leucogenys
30951 Mus musculus
57332 Homo sapiens
608591 Canis lupus familiaris
506458 Bos taurus
303731 Rattus norvegicus
496172 Xenopus laevis
100514536 Sus scrofa
422084 Gallus gallus
100150672 Danio rerio
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