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CHD1L encodes a DNA helicase protein involved in DNA repair. Additionally we are shipping CHD1L Antibodies (44) and many more products for this protein.
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Overexpression of CHD1L is positively associated with tumor metastasis of lung adenocarcinoma, and might serve as a novel prognostic biomarker and potential therapeutic target for patients.
This study identified CHD1L as a potential anti-metastasis target for therapeutic intervention in breast cancer.
Relative mRNA expression level of CHD1L was higher in breast cancer cell lines.
These results indicated that CHD1L could serve as a prognostic marker for gastric cancer
CHD1L is now considered to be a novel independent biomarker for progression, prognosis and survival in several solid tumors. [Review]
Data indicate that chromodomain helicase/ATPase DNA-binding protein (show UBE2V1 Proteins) 1-like (CHD1L) might be an diagnostic and prognostic marker for bladder cancer (BC) patients.
TRIM33 (show TRIM33 Proteins) plays a role in PARP-dependent DNA damage response and regulates ALC1 (show MYL4 Proteins) activity by promoting its timely removal from sites of DNA damage.
CHD1L is the target oncogene (show RAB1A Proteins) within the 1q21 amplicon and plays a pivotal role in colorectal carcinoma pathogenesis.
positive expression of CHD1L protein is significantly correlated with the metastasis proceeding of ovarian carcinoma, and CHD1L protein expression, as examined by IHC, may act as a novel prognostic biomarker for patients with ovarian carcinoma.
the model that PAR (show JTB Proteins) present on PARylated PARP1 (show PARP1 Proteins) acts as an allosteric effector of ALC1 (show MYL4 Proteins) nucleosome remodeling activity.
found a significant correlation of CHD1L with developmental transcriptional factors and lineage differentiation markers in clinical hepatocellular carcinoma patients
these results identify CHD1L as a key chromatin remodeler involved in PARP1 (show PARP1 Proteins)/PARylation-regulated early-stage reprogramming and pluripotency in stem cells.
TRIM33 (show TRIM33 Proteins) plays a role in PARP (show PARP1 Proteins)-dependent DNA damage response and regulates ALC1 (show MYL4 Proteins) activity by promoting its timely removal from sites of DNA damage.
CHD1L promotes hepatocellular carcinoma progression and metastasis in mice and is associated with these processes in human patients.
Reports that transgenic CHD1L (Alc1) expression induces spontaneous tumors in mice.
This gene encodes a DNA helicase protein involved in DNA repair. The protein converts ATP to add poly(ADP-ribose) as it regulates chromatin relaxation following DNA damage. Several alternatively spliced transcripts variants have been described for this gene.
chromodomain helicase DNA binding protein 1-like
, chromodomain-helicase-DNA-binding protein 1-like
, amplified in liver cancer 1
, amplified in liver cancer protein 1