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Chromogranin B (Secretogranin 1) Proteins (CHGB)

CHGB encodes a tyrosine-sulfated secretory protein abundant in peptidergic endocrine cells and neurons. Additionally we are shipping CHGB Antibodies (50) and CHGB Kits (21) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CHGB 12653 P16014
CHGB 1114 P05060
CHGB 24259 O35314
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Top CHGB Proteins at antibodies-online.com

Showing 10 out of 19 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 7 to 8 Days
$407.00
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$732.60
Details
HOST_Escherichia coli (E. coli) Rat His tag,GST tag 100 μg Log in to see 11 to 13 Days
$897.60
Details
HOST_Escherichia coli (E. coli) Cow His tag,GST tag 100 μg Log in to see 11 to 13 Days
$932.80
Details
HOST_Escherichia coli (E. coli) Wild boar His tag,GST tag 100 μg Log in to see 11 to 13 Days
$950.40
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,899.50
Details
HOST_Escherichia coli (E. coli) Human His tag   1 mg Log in to see 3 to 4 Days
$5,769.50
Details

CHGB Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
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Rat (Rattus) ,
,

Top referenced CHGB Proteins

  1. Human CHGB Protein expressed in Escherichia coli (E. coli) - ABIN667778 : Benjannet, Leduc, Adrouche, Falgueyret, Marcinkiewicz, Seidah, Mbikay, Lazure, Chretien: Chromogranin B (secretogranin I), a putative precursor of two novel pituitary peptides through processing at paired basic residues. in FEBS letters 1988 (PubMed)
    Show all 2 references for ABIN667778

More Proteins for Chromogranin B (Secretogranin 1) (CHGB) Interaction Partners

Mouse (Murine) Chromogranin B (Secretogranin 1) (CHGB) interaction partners

  1. This analysis of mice lacking Cgs highlights the important roles of CgA and CgB in glucose and cardiovascular homeostasis. This study also unveils the existence of direct implications of Cgs in the control of behaviour and mood.

  2. Chromogranin B contributes to a highly efficient system that directly mediates monoamine accumulation and exocytosis in large dense core secretory vesicles.

  3. C-terminal domain of chromogranin B regulates intracellular calcium signaling.

  4. CgB is not required for normal insulin (show INS Proteins) granule biogenesis or maintenance in vivo, but is essential for adequate secretion of islet hormones

  5. Chromogranin B gene ablation reduces the catecholamine cargo and decelerates exocytosis in chromaffin secretory vesicles in mice.

  6. CGB was localized in the nucleus; transcription control role of CGB in the nucleus

  7. These data suggest that RAGE (show AGER Proteins) signaling is capable of driving neuronal differentiation involving CREB (show CREB1 Proteins) activation and induction of chromogranin expression.

  8. Chromogranin B has a role in secretory granule biogenesis

  9. CGB may play an important modulatory role in the control of Ca2 (show CA2 Proteins)+ release from the endoplasmic reticulum

  10. Neuroendocrine-specific expression of Chgb is mediated by the CRE and G/C boxes in cis (show CISH Proteins) and the transcription factors CREB (show CREB1 Proteins), AP-2 (show TFAP2A Proteins), Egr-1 (show EGR1 Proteins) and Sp1 (show SP1 Proteins).

Human Chromogranin B (Secretogranin 1) (CHGB) interaction partners

  1. intracellular calcium binding protein (show CETN1 Proteins) Sg1 (show ZNF750 Proteins) is increased in early multiple sclerosis (MS) patients compared to relapsing-remitting MS and neurological controls.

  2. The polymorphism P413L in the CHGB gene was not associated with sporadic amyotrophic lateral sclerosis in a group of Italian patients.

  3. CgA (show CGA Proteins) and CgB (show CGB Proteins) have been used as general NEN biomarkers for many years, while CART has only recently been identified

  4. A heterogeneous response to short- and long-term physical activities among circulating granin proteins, particularly chromogranin B.

  5. CgA (show CGA Proteins), CgB (show CGB Proteins), and secretoneurin (show SCG2 Proteins) are detectable in feces, and collagenous colitis patients express higher values than patients with inflammatory bowel disease and controls. In treatment, fecal secretoneurin (show SCG2 Proteins) decreased to control levels in collagenous colitis.

  6. Our findings suggest that altered PTEN, ATRX (show ATRX Proteins), CHGA (show CHGA Proteins), and CHGB expression are associated with aggressive PNET phenotype in VHL (show VHL Proteins) and may serve as useful adjunct prognostic markers to Ki-67 (show MKI67 Proteins) in PNETs.

  7. Results do not support the 413L variant of chromogranin B as a risk factor for sporadic amyotrophic lateral sclerosis in the French population.

  8. This short review deals with investigations in neuroendocrine tumors (NETs) with antibodies against defined epitopes of chromogranins (Cgs) A and B and secretogranins (Sgs (show FBN1 Proteins)) II and III.

  9. The roles of Cgs A and B in maintaining the intravesicular environment of secretory vesicles and in exocytosis, bringing together the most recent findings from adrenal chromaffin cells, are discussed.

  10. common polymorphism in the 3'-UTR (C+84A) of CHGB, which disrupts an A/U-rich messenger ribonucleic acid stability element, associates with not only CHGB secretion but also excretion of isoprostane

Cow (Bovine) Chromogranin B (Secretogranin 1) (CHGB) interaction partners

  1. chromogranin B has a role in the IP(3)-mediated Ca(2 (show CA2 Proteins)+) release mechanism of secretory granules

  2. CGB may play an important modulatory role in the control of Ca2 (show CA2 Proteins)+ release from the endoplasmic reticulum

  3. colocalization of all three inositol 1,4,5-trisphosphate receptor (IP(3)R (show ITPR1 Proteins))isoforms with chromogranin B to the extent that the majority of each IP(3)R (show ITPR1 Proteins) isoform-labeling gold particles found in the nucleoplasm

  4. determination of the subcellular distribution of chromogranins A and B in chromaffin cells; results suggest that chromogranins are at the center of intracellular Ca(2 (show CA2 Proteins)+) homeostasis in secretory cells

  5. Chromogranin B was found to co-localize with secretogranin II (show SCG2 Proteins) and IP3 receptors in the nucleus, more specifically, in the IP3-sensitive nucleoplasmic Ca2 (show CA2 Proteins)+ store vesicles.

Pig (Porcine) Chromogranin B (Secretogranin 1) (CHGB) interaction partners

  1. expression and localization of chromogranin A (CgA (show CHGA Proteins)), chromogranin B (CgB), synaptophysin (show SYP Proteins), and insulin (show INS Proteins) were ultrastructurally studied with the immunogold technique in porcine and human pancreatic islet neuroendocrine cells

CHGB Protein Profile

Protein Summary

This gene encodes a tyrosine-sulfated secretory protein abundant in peptidergic endocrine cells and neurons. This protein may serve as a precursor for regulatory peptides.

Gene names and symbols associated with CHGB

  • chromogranin B (CHGB)
  • chromogranin B (chgb)
  • chromogranin B (Chgb)
  • chromogranin B (secretogranin 1) (CHGB)
  • chromogranin B (secretogranin 1) (Chgb)
  • CGB protein
  • CHGB protein
  • Scg-1 protein
  • SCG1 protein
  • si:ch73-355e4.2 protein
  • si:cu075930.2 protein

Protein level used designations for CHGB

chromogranin B , secretogranin-1 , cgB , chromogranin-B , secretogranin I , sgI , secretogranin B , Chromogranin B, parathyroid secretory protein , glucagonoma peptide , secretogranin-I

GENE ID SPECIES
719171 Macaca mulatta
792853 Danio rerio
12653 Mus musculus
1114 Homo sapiens
24259 Rattus norvegicus
281071 Bos taurus
397154 Sus scrofa
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