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Acts as an activator of the canonical NF-kappa-B pathway and drive the production of proinflammatory cytokines. Additionally we are shipping Chromosome 1 Open Reading Frame 190 Proteins (3) and many more products for this protein.
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Cow (Bovine) Polyclonal C1orf190 Primary Antibody for WB - ABIN2786572
Gregory, Barlow, McLay, Kaul, Swarbreck, Dunham, Scott, Howe, Woodfine, Spencer, Jones, Gillson, Searle, Zhou, Kokocinski, McDonald, Evans, Phillips, Atkinson, Cooper, Jones, Hall, Andrews, Lloyd et al.: The DNA sequence and biological annotation of human chromosome 1. ... in Nature 2006
C1orf190 can activate NF-kappaB (show NFKB1 Antibodies), drive production of cytokines, and promote the antigen-presenting function and priming ability of dendritic cells.
Acts as an activator of the canonical NF-kappa-B pathway and drive the production of proinflammatory cytokines. Promotes the antigen (Ag)-presenting and priming function of dendritic cells via the canonical NF-kappa-B pathway. In concert with MYO18A and CDC42BPA/CDC42BPB, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. Activates CDC42BPA/CDC42BPB and targets it to actomyosin through its interaction with MYO18A, leading to MYL9/MLC2 phosphorylation and MYH9/MYH10-dependent actomyosin assembly in the lamella (By similarity).
chromosome 1 open reading frame 190
, NF-kappa-B activator C1orf190
, leucine repeat adapter protein 35A
, leucine repeat adaptor protein 35a
, NF-kappa-B activator C1orf190 homolog
, adaptor protein LRAP35a