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Chromosome 11 Open Reading Frame 30 Proteins (C11orf30)

Regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin. Additionally we are shipping Chromosome 11 Open Reading Frame 30 Antibodies (36) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
C11orf30 56946 Q7Z589
C11orf30 233545 Q8BMB0
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Top Chromosome 11 Open Reading Frame 30 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

C11orf30 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Chromosome 11 Open Reading Frame 30 (C11orf30) Interaction Partners

Human Chromosome 11 Open Reading Frame 30 (C11orf30) interaction partners

  1. identify a novel substoichiometric interactor of the complex, transcription factor ZNF131 (show ZNF131 Proteins), which recruits EMSY to a large number of active, H3K4me3 marked promoters.

  2. Eosinophilic esophagitis was associate with increased expression of C11orf30.

  3. The association of higher levels of expression of C11orf30 may be involved in transcription repression of interferon (show IFNA Proteins)-stimulated genes, and its association with sensitization to multiple allergens suggest that this locus is highly relevant for atopy.

  4. Our study demonstrated that EMSY played an oncogenic role in the progression of ovarian cancer cells and EMSY might be a promising target for the treatment

  5. Univariate analysis revealed a significant positive association between EMSY expression and lymph node metastasis, larger tumor size, as well as a non-significant relation with increased risk of recurrence.

  6. EMSY is recruited to the miR (show MLXIP Proteins)-31 promoter by the DNA binding factor ETS-1 (show ETS1 Proteins), and it represses miR (show MLXIP Proteins)-31 transcription by delivering the H3K4me3 demethylase JARID1b/PLU-1 (show KDM5B Proteins)/KDM5B (show KDM5B Proteins)

  7. Akt1 (show AKT1 Proteins) regulates the interferon (show IFNA Proteins) response through phosphorylation of the transcriptional repressor EMSY

  8. There are 2 independent signals, one in C11orf30 and the other in LRRC32, that are strongly associated with serum IgE levels. C11orf30-LRRC32 region may represent a common locus for atopic diseases via pathways involved in regulation of serum IgE levels

  9. EMSY amplification does occur independently of CCND1 (show CCND1 Proteins) amplification in a minority of familial breast cancers, supporting its role as a possible breast cancer oncogene (show RAB1A Proteins)

  10. EMSY amplification may mimic BRCA2 (show BRCA2 Proteins) deficiency, at least by overriding RPA (show RPA1 Proteins) and PALB2 (show PALB2 Proteins), crippling the BRCA2 (show BRCA2 Proteins)/RAD51 (show RAD51 Proteins) complex at DNA-damage and replication/transcription sites

Mouse (Murine) Chromosome 11 Open Reading Frame 30 (C11orf30) interaction partners

  1. Akt1 (show AKT1 Proteins) regulates the interferon (show IFNA Proteins) response through phosphorylation of the transcriptional repressor EMSY

Chromosome 11 Open Reading Frame 30 (C11orf30) Protein Profile

Protein Summary

Regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin. Its interaction with BRCA2 suggests that it may play a central role in the DNA repair function of BRCA2.

Gene names and symbols associated with C11orf30

  • chromosome 11 open reading frame 30 (C11orf30)
  • RIKEN cDNA 2210018M11 gene (2210018M11Rik)
  • zgc:56039 (zgc:56039)
  • 2210018M11RIK protein
  • 2310016L09Rik protein
  • AU019521 protein
  • AU019557 protein
  • emsy protein
  • fj36b04 protein
  • wu:fj36b04 protein

Protein level used designations for C11orf30

chromosome 11 open reading frame 30 , EMSY protein , protein EMSY

GENE ID SPECIES
419090 Gallus gallus
56946 Homo sapiens
233545 Mus musculus
335889 Danio rerio
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