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Induces contraction of stomach muscle (By similarity). Additionally we are shipping Chromosome 12 Open Reading Frame 39 Kits (4) and many more products for this protein.
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Circulating spexin levels are low in T2DM patients and negatively related to blood glucose and lipids suggesting that the peptide may play a role in glucose and lipid metabolism in T2DM.
Data from ligand-receptor interaction studies suggest that human spexin-1 and zebrafish spexin-2 activate galanin (show GAL Antibodies) receptors GALR2 (show GALR2 Antibodies)/GALR3 (show GALR3 Antibodies) (but not GALR1 (show GALR1 Antibodies)); thus spexins appear to be natural ligands for human/Xenopus/zebrafish GALR2 (show GALR2 Antibodies)/GALR3 (show GALR3 Antibodies).
newly identified peptides derived from the NPQ/spexin precursor contribute to CNS-mediated control of arterial blood pressure and salt and water balance and modulate nociceptive responses
Taken together, although C12ORF39 is not a secreted small peptide, it can also be secreted to play a role in the biological functions of the placenta.
Induces contraction of stomach muscle (By similarity).
, neuropeptide Q