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Induces contraction of stomach muscle (By similarity). Additionally we are shipping Chromosome 12 Open Reading Frame 39 Antibodies (29) and many more products for this protein.
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Human C12orf39 ELISA Kit for Sandwich ELISA - ABIN830436
Gu, Ma, Gu, Zhang, Yan, Li, Wang, Ding, Yin, Fan, Peng: Spexin peptide is expressed in human endocrine and epithelial tissues and reduced after glucose load in type 2 diabetes. in Peptides 2015
Circulating spexin levels are low in T2DM patients and negatively related to blood glucose and lipids suggesting that the peptide may play a role in glucose and lipid metabolism in T2DM.
Data from ligand-receptor interaction studies suggest that human spexin-1 and zebrafish spexin-2 activate galanin (show GAL ELISA Kits) receptors GALR2 (show GALR2 ELISA Kits)/GALR3 (show GALR3 ELISA Kits) (but not GALR1 (show GALR1 ELISA Kits)); thus spexins appear to be natural ligands for human/Xenopus/zebrafish GALR2 (show GALR2 ELISA Kits)/GALR3 (show GALR3 ELISA Kits).
newly identified peptides derived from the NPQ/spexin precursor contribute to CNS-mediated control of arterial blood pressure and salt and water balance and modulate nociceptive responses
Taken together, although C12ORF39 is not a secreted small peptide, it can also be secreted to play a role in the biological functions of the placenta.
Induces contraction of stomach muscle (By similarity).
, neuropeptide Q