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Induces contraction of stomach muscle (By similarity). Additionally we are shipping Chromosome 12 Open Reading Frame 39 Kits (5) and many more products for this protein.
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The results suggest that C12orf39, CSTA (show CSTA Antibodies), and CALCB (show CALCB Antibodies) are novel ATF4 (show ATF4 Antibodies) target genes, and that C12orf39 promoter activity is activated by ATF4 (show ATF4 Antibodies) through amino acid response element.
Circulating spexin levels are low in T2DM patients and negatively related to blood glucose and lipids suggesting that the peptide may play a role in glucose and lipid metabolism in T2DM.
Data from ligand-receptor interaction studies suggest that human spexin-1 and zebrafish spexin-2 activate galanin (show GAL Antibodies) receptors GALR2 (show GALR2 Antibodies)/GALR3 (show GALR3 Antibodies) (but not GALR1 (show GALR1 Antibodies)); thus spexins appear to be natural ligands for human/Xenopus/zebrafish GALR2 (show GALR2 Antibodies)/GALR3 (show GALR3 Antibodies).
newly identified peptides derived from the NPQ/spexin precursor contribute to CNS-mediated control of arterial blood pressure and salt and water balance and modulate nociceptive responses
Taken together, although C12ORF39 is not a secreted small peptide, it can also be secreted to play a role in the biological functions of the placenta.
Induces contraction of stomach muscle (By similarity).
, neuropeptide Q