anti-Chromosome 12 Open Reading Frame 39 (C12orf39) Antibodies

Induces contraction of stomach muscle (By similarity). Additionally we are shipping Chromosome 12 Open Reading Frame 39 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
Anti-Human C12orf39 C12orf39 80763 Q9BT56
Anti-Rat C12orf39 C12orf39 691138  
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More Antibodies against Chromosome 12 Open Reading Frame 39 Interaction Partners

Human Chromosome 12 Open Reading Frame 39 (C12orf39) interaction partners

  1. Lower circulating levels of Spexin in obese children compared with their normal-weight counterparts and the ability to discriminate obese and normal-weight groups based on Spexin concentration enabled us to suggest a potential role for this novel peptide in childhood obesity.

  2. The results suggest that C12orf39, CSTA (show CSTA Antibodies), and CALCB (show CALCB Antibodies) are novel ATF4 (show ATF4 Antibodies) target genes, and that C12orf39 promoter activity is activated by ATF4 (show ATF4 Antibodies) through amino acid response element.

  3. Circulating spexin levels are low in T2DM patients and negatively related to blood glucose and lipids suggesting that the peptide may play a role in glucose and lipid metabolism in T2DM.

  4. Data from ligand-receptor interaction studies suggest that human spexin-1 and zebrafish spexin-2 activate galanin (show GAL Antibodies) receptors GALR2 (show GALR2 Antibodies)/GALR3 (show GALR3 Antibodies) (but not GALR1 (show GALR1 Antibodies)); thus spexins appear to be natural ligands for human/Xenopus/zebrafish GALR2 (show GALR2 Antibodies)/GALR3 (show GALR3 Antibodies).

  5. newly identified peptides derived from the NPQ/spexin precursor contribute to CNS-mediated control of arterial blood pressure and salt and water balance and modulate nociceptive responses

  6. Taken together, although C12ORF39 is not a secreted small peptide, it can also be secreted to play a role in the biological functions of the placenta.

Chromosome 12 Open Reading Frame 39 (C12orf39) Antigen Profile

Protein Summary

Induces contraction of stomach muscle (By similarity).

Gene names and symbols associated with C12orf39

  • chromosome 12 open reading frame 39 (C12orf39) antibody
  • chromosome 5 open reading frame, human C12orf39 (C5H12orf39) antibody
  • hypothetical protein LOC691138 (LOC691138) antibody
  • Npq antibody
  • Spx antibody

Protein level used designations for C12orf39

NPQ , neuropeptide Q , spexin , LRRGT00060

80763 Homo sapiens
509493 Bos taurus
691138 Rattus norvegicus
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