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Autophagy factor required for autophagosome formation (By similarity). Additionally we are shipping Chromosome 12 Open Reading Frame 44 Proteins (7) and Chromosome 12 Open Reading Frame 44 Kits (4) and many more products for this protein.
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Human Polyclonal C12orf44 Primary Antibody for EIA, IF - ABIN783665
Kamada, Funakoshi, Shintani, Nagano, Ohsumi, Ohsumi: Tor-mediated induction of autophagy via an Apg1 protein kinase complex. in The Journal of cell biology 2000
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Structure of the human Atg13 (show ATG13 Antibodies)-Atg101 HORMA heterodimer in the ULK1 (show ULK1 Antibodies) complex that controls autophagy has been described.
Data indicate mitogen lacritin stimulates FOXO3 (show FOXO3 Antibodies)-ATG101 and FOXO1 (show FOXO1 Antibodies)-ATG7 (show ATG7 Antibodies) autophagic coupling and restores metabolic homeostasis.
The identification of the novel protein, Atg101, and the validation of Atg13 (show ATG13 Antibodies) and Atg101 as ULK1 (show ULK1 Antibodies)-interacting proteins, suggests an Atg1 (show ULK1 Antibodies) complex is involved in the induction of macroautophagy in mammalian cells.
These data suggest that Atg101 is a novel Atg protein that functions together with ULK, Atg13 (show ATG13 Antibodies) and FIP200 (show RB1CC1 Antibodies).
Autophagy factor required for autophagosome formation (By similarity).
, autophagy-related protein 101