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anti-Chromosome 12 Open Reading Frame 52 (C12orf52) Antibodies

Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Additionally we are shipping Chromosome 12 Open Reading Frame 52 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
C12orf52 84934 Q96K30
Anti-Mouse C12orf52 C12orf52 100764 Q9D1H0
Anti-Rat C12orf52 C12orf52 288683 Q2KJ10
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Top anti-Chromosome 12 Open Reading Frame 52 Antibodies at antibodies-online.com

Showing 10 out of 24 products:

Catalog No. Reactivity Host Conjugate Application Quantity Supplier Delivery Price Details
Human Rabbit Alkaline Phosphatase (AP) ELISA, WB 200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated ELISA 200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Alexa Fluor 350 IF (p) 100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 555 IF (p) 100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 488 IF (p) 100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 647 IF (p) 100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit FITC IF (p) 100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Biotin IHC (p) 100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 594 IF (p) 100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Cy3 IF (p) 100 μL Log in to see 14 to 21 Days
$379.50
Details

C12orf52 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,


, , , , , , , , , , , , , ,

More Antibodies against Chromosome 12 Open Reading Frame 52 Interaction Partners

Xenopus laevis Chromosome 12 Open Reading Frame 52 (C12orf52) interaction partners

  1. The study reports the identification and functional characterization of rbpj interacting and tubulin associated (RITA) (C12ORF52) as a novel rbpj/CBF-1 (show RBPJ Antibodies)-interacting protein.

Human Chromosome 12 Open Reading Frame 52 (C12orf52) interaction partners

  1. RITA (show ZNF331 Antibodies) overexpression increased expression of p53 (show TP53 Antibodies) and Fbxw7 (show FBXW7 Antibodies) and downregulated expression of cyclin D1 (show CCND1 Antibodies), cyclin E (show CCNE1 Antibodies), CDK2 (show CDK2 Antibodies), Hes-1 and NF-kappaB (show NFKB1 Antibodies) p65 (show GORASP1 Antibodies). These changes led to growth inhibition and induced G0/G1 cell cycle arrest and apoptosis in SMMC7721 and HepG2 cells.

  2. human RITA (show ZNF331 Antibodies), binding to Drosophila Su(H (show RBPJ Antibodies)) and tubulin (show TUBB Antibodies), cannot influence the Notch (show NOTCH1 Antibodies) signalling pathway in the fly

  3. RITA (show ZNF331 Antibodies) might suppress tumor growth and induce apoptosis in hepatocellular carcinoma.

Chromosome 12 Open Reading Frame 52 (C12orf52) Antigen Profile

Protein Summary

Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis (By similarity).

Gene names and symbols associated with C12orf52

  • chromosome 12 open reading frame 52 (C12orf52) antibody
  • chromosome 12 open reading frame 52 (c12orf52) antibody
  • chromosome 17 open reading frame, human C12orf52 (C17H12orf52) antibody
  • RIKEN cDNA 1110008J03 gene (1110008J03Rik) antibody
  • similar to RIKEN cDNA 1110008J03 (RGD1306772) antibody
  • AI853657 antibody
  • C12orf52 antibody
  • C86297 antibody
  • Rita antibody

Protein level used designations for C12orf52

chromosome 12 open reading frame 52 , RBP-J interacting and tubulin associated , RBPJ-interacting and tubulin-associated protein

GENE ID SPECIES
712837 Macaca mulatta
100381047 Xenopus laevis
84934 Homo sapiens
533158 Bos taurus
100764 Mus musculus
288683 Rattus norvegicus
Selected quality suppliers for anti-Chromosome 12 Open Reading Frame 52 (C12orf52) Antibodies
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