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Chromosome 13 Open Reading Frame 15 Proteins (C13orf15)

C13orf15 is thought to regulate cell cycle progression. Additionally we are shipping Chromosome 13 Open Reading Frame 15 Antibodies (18) and Chromosome 13 Open Reading Frame 15 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
C13orf15 28984 Q9H4X1
C13orf15 66214 Q9DBX1
Rat C13orf15 C13orf15 117183 Q9Z2P4
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Top Chromosome 13 Open Reading Frame 15 Proteins at antibodies-online.com

Showing 4 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

C13orf15 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Chromosome 13 Open Reading Frame 15 (C13orf15) Interaction Partners

Human Chromosome 13 Open Reading Frame 15 (C13orf15) interaction partners

  1. RGC-32 expression on M2-polarized and tumor-associated macrophages is M-CSF (show CSF1 Proteins)-dependent and enhanced by tumor-derived IL-4 (show IL4 Proteins).

  2. Data suggest that expression of RGC32 is down-regulated in placental trophoblasts in women with pre-eclampsia as compared to women with normal term pregnancies; silencing RGC32 expression by RNA interference inhibits trophoblast migration/invasion.

  3. Suggest that RGC32 is involved in tumorigenesis of human lung cancer, inducing apoptosis and inhibiting cell growth, migration, and invasion.

  4. In conclusion, the present study indicates that C5a may promote the proliferation of breast cancer cells through Akt1 (show AKT1 Proteins) activation of the RGC-32 gene.

  5. results demonstrate for the first time that RGC-32 is a novel membrane regulator for macrophage phagocytosis.

  6. RGC32 promotes cell migration and invasion and induces epithelial-mesenchymal transition in lung cancer cells via the NF-kappaB (show NFKB1 Proteins) signaling pathway.

  7. data suggest RGC-32 plays a dual role in multiple sclerosis, both as a regulator of T-cells mediated apoptosis and as a promoter of TGF-beta (show TGFB1 Proteins)-mediated profibrotic effects in astrocytes

  8. analysis of upregulation of the cell-cycle regulator RGC-32 in Epstein-Barr virus-immortalized cells, due to transcriptional activation by high levels of the differentially expressed RUNX1c transcription factor

  9. Data demonstrate that RGC-32 interacts with Smad3 (show SMAD3 Proteins) to mediate the epithelial-mesenchymal transition of human renal proximal tubular cells.

  10. methylation-associated down-regulation of RGC32 plays an important role in the pathogenesis of NSCLC, particularly in females

Mouse (Murine) Chromosome 13 Open Reading Frame 15 (C13orf15) interaction partners

  1. results demonstrate that RGC-32 contributes to the development of hepatic steatosis by facilitating de novo lipogenesis through activating liver X receptor, leading to the induction of SREBP-1c (show SREBF1 Proteins) and its target genes

  2. RGC-32 is involved in controlling the cell cycle of T cells in vivo, and this effect is mediated by IL-2 (show IL2 Proteins) in a PI3K-dependent fashion.

  3. RGC32 plays an important role in diet-induced obesity and insulin (show INS Proteins) resistance, and thus it may serve as a potential novel drug target for developing therapeutics to treat obesity and metabolic disorders.

  4. results demonstrate for the first time that RGC-32 is a novel membrane regulator for macrophage phagocytosis.

  5. knockdown of RGC-32 by shRNA inhibited VEGF (show VEGFA Proteins)-induced endothelial cell proliferation, migration, and tube formation while blocking VEGFR2 (show KDR Proteins) expression.

  6. RGC-32 as a novel fibrogenic factor contributing to the pathogenesis of renal fibrosis through fibroblast activation.

  7. Smad2 (show SMAD2 Proteins) and PEA3 (show ETV4 Proteins) regulate RGC-32 transcription which is essential for smooth muscle cell differentiation from neural crest cells.

Chromosome 13 Open Reading Frame 15 (C13orf15) Protein Profile

Protein Summary

This gene is thought to regulate cell cycle progression. It is induced by p53 in response to DNA damage, or by sublytic levels of complement system proteins that result in activation of the cell cycle. The encoded protein localizes to the cytoplasm during interphase and to centrosomes during mitosis. The protein forms a complex with polo-like kinase 1. The protein also translocates to the nucleus in response to treatment with complement system proteins, and can associate with and increase the kinase activity of cell division cycle 2 protein. In different assays and cell types, overexpression of this protein has been shown to activate or suppress cell cycle progression.

Gene names and symbols associated with C13orf15

  • regulator of cell cycle (RGCC)
  • regulator of cell cycle (Rgcc)
  • response gene to complement 32 protein (RGC32)
  • similar to response gene to complement 32 (LOC683573)
  • 1190002H23Rik protein
  • bA157L14.2 protein
  • C13orf15 protein
  • Rgc-32 protein
  • Rgc32 protein

Protein level used designations for C13orf15

regulator of cell cycle RGCC , response gene to complement 32 protein , RGC-32

GENE ID SPECIES
28984 Homo sapiens
66214 Mus musculus
117183 Rattus norvegicus
100625944 Sus scrofa
683573 Rattus norvegicus
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