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Chromosome 18 Open Reading Frame 8 Proteins (C18orf8)

Bone morphogenetic proteins (e.g., BMP9\; MIM 605120) are members of the transforming growth factor-beta (see TGFB1\; MIM 190180) superfamily and regulate tissue differentiation and maintenance. Additionally we are shipping C18orf8 Antibodies (64) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
C18orf8 29919 Q96DM3
C18orf8 76482 Q8VC42
Rat C18orf8 C18orf8 291784  
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Top C18orf8 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

C18orf8 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Chromosome 18 Open Reading Frame 8 (C18orf8) Interaction Partners

Human Chromosome 18 Open Reading Frame 8 (C18orf8) interaction partners

  1. High MIC-1 expression is associated with weight loss and poor response to chemotherapy in esophageal squamous cell carcinoma.

  2. Study describes for the first time the vital role of GDF15 (show GDF15 Proteins) both in tumorigenesis and in radioresistance of OSCC cells. With its anti-apoptotic effects, GDF15 (show GDF15 Proteins) possibly promotes tumor progression and might protect carcinoma cells against irradiation effects.

  3. GDF15 might play an important role in cellular senescence through a ROS-mediated p16 pathway and contribute to the pathogenesis of atherosclerosis via pro-senescent activity.

  4. High level of GDF15 (show GDF15 Proteins) expression is associated with breast cancer.

  5. To investigate a possible association between GDF-15 (show GDF15 Proteins) levels and DNA methylation (show HELLS Proteins), we performed a genome-wide DNA methylation (show HELLS Proteins) study of white blood cells . This study shows that GDF-15 (show GDF15 Proteins) levels are associated with differences in DNA methylation (show HELLS Proteins) in blood cells, and a subset of the loci are also differentially methylated in participants with Myocadial Infarction

  6. This is the first report showing that GDF-15 (show GDF15 Proteins) appears to be expressed in the vitreous, and that its expression is significantly higher in the presence of a vitreoretinal disorder in which there is an inflammatory component.

  7. Missense GDF15 (show GDF15 Proteins) mutations are associated with oral squamous cell carcinoma.

  8. Review/Meta-analysis: High plasma GDF-15 (show GDF15 Proteins) levels are associated with an increased risk of mortality and recurrent myocardial infarction in patients with acute coronary syndrome.

  9. Data suggest that growth differentiation factor 15 (GDF15 (show GDF15 Proteins)) may promote colorectal cancer metastasis through activating epithelial-mesenchymal transition (EMT (show ITK Proteins)), and could be considered as a prognostic clinical marker for colorectal cancer (CRC (show CALR Proteins)).

  10. MIC1 may have a role in colorectal adenoma in women, especially multiple, large, and proximal adenomas

C18orf8 Protein Profile

Protein Summary

Bone morphogenetic proteins (e.g., BMP9\; MIM 605120) are members of the transforming growth factor-beta (see TGFB1\; MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.

Gene names and symbols associated with C18orf8

  • chromosome 18 open reading frame 8 (C18orf8)
  • chromosome 18 open reading frame 8 (c18orf8)
  • growth differentiation factor 15 (GDF15)
  • RIKEN cDNA 3110002H16 gene (3110002H16Rik)
  • similar to RIKEN cDNA 2400010D15 (RGD1311805)
  • 2400010D15Rik protein
  • C18orf8 protein
  • GDF-15 protein
  • HsT2591 protein
  • MIC-1 protein
  • Mic1 protein
  • NAG-1 protein
  • PDF protein
  • PLAB protein
  • PTGFB protein

Protein level used designations for C18orf8

chromosome 18 open reading frame 8 , hypothetical protein LOC100124886 , hypothetical protein LOC100137621 , colon cancer-associated protein Mic1 , uncharacterized protein C18orf8 , NRG-1 , NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1 , NSAID-activated gene 1 protein , NSAID-regulated gene 1 protein , PTGF-beta , growth/differentiation factor 15 , macrophage inhibitory cytokine 1 , placental TGF-beta , placental bone morphogenetic protein , prostate differentiation factor , colon cancer-associated protein Mic1 homolog , uncharacterized protein C18orf8 homolog , uncharacterized protein LOC291784

GENE ID SPECIES
421075 Gallus gallus
100124886 Xenopus (Silurana) tropicalis
100137621 Xenopus laevis
29919 Homo sapiens
9518 Homo sapiens
76482 Mus musculus
291784 Rattus norvegicus
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