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Bone morphogenetic proteins (e.g., BMP9\; MIM 605120) are members of the transforming growth factor-beta (see TGFB1\; MIM 190180) superfamily and regulate tissue differentiation and maintenance. Additionally we are shipping C18orf8 Proteins (4) and many more products for this protein.
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Human Polyclonal C18orf8 Primary Antibody for EIA, WB - ABIN359557
Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: Complete sequencing and characterization of 21,243 full-length human cDNAs. ... in Nature genetics 2003
Show all 2 references for ABIN359557
Human Polyclonal C18orf8 Primary Antibody for FACS, IF - ABIN655711
Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. in Cell 2006
GDF-15 (show GDF15 Antibodies) captures distinct aspects of cardiovascular disease development, progression, and prognosis, which are not represented by clinical risk predictors and other biomarkers. The usefulness of GDF-15 (show GDF15 Antibodies) to guide management decisions and discover new treatment targets should be further explored.
In stable Coronary Heart Disease, GDF-15 (show GDF15 Antibodies) was independently associated with cardiovascular (CV), non-CV, and cancer mortality, as well as with MI and stroke. When also adjusting for other prognostic biomarkers, the associations to all fatal and nonfatal events were maintained except for MI. Information on GDF-15 (show GDF15 Antibodies), therefore, might be helpful when assessing the risk of adverse outcomes in patients with stable CHD (show CHDH Antibodies).
Impaired glucose tolerance is associated with increased GDF-15 (show GDF15 Antibodies) levels even in the absence of anemia
GDF15 (show GDF15 Antibodies) is a potent mitohormetic signal that safeguards against the onset of obesity and insulin (show INS Antibodies) resistance.
NAG-1 (show GDF15 Antibodies) expression was transcriptionally upregulated by CHOP (show DDIT3 Antibodies), which promoted chemokine (show CCL1 Antibodies) production through sustained NF-kappaB (show NFKB1 Antibodies) activation.
ChIP studies showed that the S100A4 (show S100A4 Antibodies) protein binds to the GDF15 (show GDF15 Antibodies) promoter, implicating S100A4 (show S100A4 Antibodies) in GDF15 (show GDF15 Antibodies) regulation at the transcriptional level.
Study compared the diagnostic utility of GDF-15 (show GDF15 Antibodies) with FGF-21 (show FGF21 Antibodies) in an adult mitochondrial disease cohort. GDF-15 (show GDF15 Antibodies) outperforms FGF-21 (show FGF21 Antibodies) as an indicator of mitochondrial diseases. GDF-15 (show GDF15 Antibodies) is generally indicative of inherited mitochondrial disease regardless of clinical phenotype, whereas FGF-21 (show FGF21 Antibodies) seems to be more indicative of mitochondrial disease when muscle manifestations are present
MIC1/GDF15 (show GDF15 Antibodies) may have a role in monitoring bone metastases
GDF15 (show GDF15 Antibodies) contributes to fibroblast activation and may be a novel functional secreted molecule for diffuse gastric cancer progression
MIC-1 was involved in the development of MBD (show DPEP1 Antibodies) in patients with MM by promoting the osteoclastic differentiation of PBMNCs by activating the RANKL (show TNFSF11 Antibodies)-Erk1/2 (show MAPK1/3 Antibodies) signaling pathway.
Bone morphogenetic proteins (e.g., BMP9\; MIM 605120) are members of the transforming growth factor-beta (see TGFB1\; MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.
chromosome 18 open reading frame 8
, hypothetical protein LOC100124886
, hypothetical protein LOC100137621
, colon cancer-associated protein Mic1
, uncharacterized protein C18orf8
, NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1
, NSAID-activated gene 1 protein
, NSAID-regulated gene 1 protein
, growth/differentiation factor 15
, macrophage inhibitory cytokine 1
, placental TGF-beta
, placental bone morphogenetic protein
, prostate differentiation factor
, colon cancer-associated protein Mic1 homolog
, uncharacterized protein C18orf8 homolog
, uncharacterized protein LOC291784