anti-Chromosome 2 Open Reading Frame 40 (C2orf40) Antibodies

Probable hormone that may induce senescence of oligodendrocyte and neural precursor cells, characterized by G1 arrest, RB1 dephosphorylation and accelerated CCND1 and CCND3 proteasomal degradation.. Additionally we are shipping Chromosome 2 Open Reading Frame 40 Proteins (6) and Chromosome 2 Open Reading Frame 40 Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
C2orf40 84417 Q9H1Z8
C2orf40 78896 Q99LS0
C2orf40 363225 D4A540
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Top anti-Chromosome 2 Open Reading Frame 40 Antibodies at antibodies-online.com

Showing 10 out of 62 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF, IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human testis tissue, using ECRG4 Antibody. The picture on the right is treated with the synthesized peptide. Immunofluorescence analysis of A549 cells, using ECRG4 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: ECRG4 Antibody [NBP1-84911] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Negative control (vector only transfected HEK293T lysate).Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY403168) Immunohistochemistry-Paraffin: ECRG4 Antibody [NBP1-84911] - Staining of human skeletal muscle shows strong cytoplasmic positivity in myocytes. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated IF, IHC (p), ELISA 100 μL Log in to see 7 to 9 Days
$478.50
Details
Human Rabbit Un-conjugated EIA, IF, WB   0.1 mg Log in to see 12 to 15 Days
$375.38
Details
Human Mouse Un-conjugated FACS, WB HEK293T cells transfected with either RC206239 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-C2orf40 antibody (ABIN2454466), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY C2orf40 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-C2orf40. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, WB 100 μL Log in to see 7 to 9 Days
$493.17
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Paraformaldehyde-fixed, paraffin embedded rat adrenal gland; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with ECRG4 Polyclonal Antibody, Unconjugated (bs-9807R) at 1:500 overnight at 4°C, followed by a conjugated secondary for 20 minutes and DAB staining. 100 μL Log in to see 3 to 7 Days
$295.90
Details
Human Mouse Un-conjugated FACS, IF, WB 100 μL Log in to see 7 to 9 Days
$529.83
Details
Human Rabbit Un-conjugated ICC, IHC (p), ELISA, WB   50 μg Log in to see 7 to 9 Days
$451.00
Details
Human Rabbit Un-conjugated ICC, IHC, IP, WB   100 μg Log in to see 13 to 16 Days
$386.00
Details

C2orf40 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Chromosome 2 Open Reading Frame 40 Antibodies

  1. Human Polyclonal C2orf40 Primary Antibody for IHC, IHC (p) - ABIN4306960 : Baird, Coimbra, Dang, Lopez, Lee, Krzyzaniak, Winfield, Potenza, Eliceiri: Cell surface localization and release of the candidate tumor suppressor Ecrg4 from polymorphonuclear cells and monocytes activate macrophages. in Journal of leukocyte biology 2012 (PubMed)
    Show all 2 Pubmed References

More Antibodies against Chromosome 2 Open Reading Frame 40 Interaction Partners

Human Chromosome 2 Open Reading Frame 40 (C2orf40) interaction partners

  1. UBR5 (show UBR5 Antibodies) directly binds to the tumor suppressor esophageal cancer-related gene 4, increasing its ubiquitination to reducing the protein stability of ECRG4 to promote colorectal cancer progression.

  2. positive and negative regulatory elements controlling ECRG4 expression include a counter regulation between promoter methylation and Sp1 (show PSG1 Antibodies) activation.

  3. the overexpression of Beclin 1 (show BECN1 Antibodies) promoted apoptosis and decreased invasion by upregulating the expression of ECRG4 in A549 lung adenocarcinoma cells. Therefore, the selection of Beclin l as a target for gene therapy represents a more effective method for the treatment of lung cancer.

  4. Downregulated ECRG4 is correlated with lymph node metastasis in nasopharyngeal carcinoma

  5. The overexpression of ECRG4 inhibited tumorigenesis.

  6. ECRG4 may be a tumor suppressor in renal cancer and serve as a prognostic marker

  7. low expression or no expression of ECRG4 in esophageal cancer tissues was closely related to the degree of tumor invasion level, TNM (show ODZ1 Antibodies) staging, lymph node metastasis and recurrence and survival after surgery.

  8. loss of ECRG4 protein expression may be involved in tumor progression and may serve as a prognostic biomarker for breast cancer.

  9. Overexpression of ECRG4 inhibited laryngeal cancer cell proliferation and induced cancer cell apoptosis.

  10. Our data suggest that methylation-mediated suppression of the ECRG4 gene occurs frequently in nasopharyngeal carcinoma

Mouse (Murine) Chromosome 2 Open Reading Frame 40 (C2orf40) interaction partners

  1. proteolytic cleavage by furin (show FURIN Antibodies) is a posttranslational requirement for proaugurin to suppress cell proliferation

  2. identified esophageal cancer-related gene 4 (Ecrg4) as a senescence inducer with implications for the senescence-like state of postmitotic cells in the aging brain.

  3. ECRG4 level in differentiated chondrocytes is decreased during hypertrophic maturation

Chromosome 2 Open Reading Frame 40 (C2orf40) Antigen Profile

Protein Summary

Probable hormone that may induce senescence of oligodendrocyte and neural precursor cells, characterized by G1 arrest, RB1 dephosphorylation and accelerated CCND1 and CCND3 proteasomal degradation.

Gene names and symbols associated with C2orf40

  • esophageal cancer related gene 4 protein (LOC100345571) antibody
  • chromosome 2 open reading frame 40 (C2orf40) antibody
  • chromosome 11 open reading frame, human C2orf40 (C11H2orf40) antibody
  • chromosome 2 open reading frame 40 (c2orf40) antibody
  • RIKEN cDNA 1500015O10 gene (1500015O10Rik) antibody
  • similar to RIKEN cDNA 1500015O10 (RGD1305645) antibody
  • Ecrg4 antibody
  • ecrg4-A antibody

Protein level used designations for C2orf40

esophageal cancer related gene 4 protein , augurin , esophageal cancer-related gene 4 protein , UPF0689 protein C2orf40 homolog , esophageal cancer-related gene 4 protein homolog

GENE ID SPECIES
100345571 Oryctolagus cuniculus
713611 Macaca mulatta
515133 Bos taurus
84417 Homo sapiens
373779 Xenopus laevis
78896 Mus musculus
363225 Rattus norvegicus
Selected quality suppliers for anti-Chromosome 2 Open Reading Frame 40 (C2orf40) Antibodies
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