Chromosome 2 Open Reading Frame 40 Proteins (C2orf40)

Probable hormone that may induce senescence of oligodendrocyte and neural precursor cells, characterized by G1 arrest, RB1 dephosphorylation and accelerated CCND1 and CCND3 proteasomal degradation.. Additionally we are shipping Chromosome 2 Open Reading Frame 40 Antibodies (62) and Chromosome 2 Open Reading Frame 40 Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
C2orf40 84417 Q9H1Z8
Mouse C2orf40 C2orf40 78896 Q99LS0
C2orf40 363225 D4A540
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Top Chromosome 2 Open Reading Frame 40 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$2,053.33
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 60 to 71 Days
$2,057.00
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 60 to 71 Days
$2,057.00
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$2,057.00
Details
HOST_Escherichia coli (E. coli) Human T7 tag,His tag   100 μg Log in to see 15 to 18 Days
$662.00
Details

C2orf40 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Rat (Rattus)

More Proteins for Chromosome 2 Open Reading Frame 40 (C2orf40) Interaction Partners

Human Chromosome 2 Open Reading Frame 40 (C2orf40) interaction partners

  1. UBR5 directly binds to the tumor suppressor esophageal cancer-related gene 4, increasing its ubiquitination to reducing the protein stability of ECRG4 to promote colorectal cancer progression.

  2. positive and negative regulatory elements controlling ECRG4 expression include a counter regulation between promoter methylation and Sp1 (show PSG1 Proteins) activation.

  3. the overexpression of Beclin 1 (show BECN1 Proteins) promoted apoptosis and decreased invasion by upregulating the expression of ECRG4 in A549 lung adenocarcinoma cells. Therefore, the selection of Beclin l as a target for gene therapy represents a more effective method for the treatment of lung cancer.

  4. Downregulated ECRG4 is correlated with lymph node metastasis in nasopharyngeal carcinoma

  5. The overexpression of ECRG4 inhibited tumorigenesis.

  6. ECRG4 may be a tumor suppressor in renal cancer and serve as a prognostic marker

  7. low expression or no expression of ECRG4 in esophageal cancer tissues was closely related to the degree of tumor invasion level, TNM (show ODZ1 Proteins) staging, lymph node metastasis and recurrence and survival after surgery.

  8. loss of ECRG4 protein expression may be involved in tumor progression and may serve as a prognostic biomarker for breast cancer.

  9. Overexpression of ECRG4 inhibited laryngeal cancer cell proliferation and induced cancer cell apoptosis.

  10. Our data suggest that methylation-mediated suppression of the ECRG4 gene occurs frequently in nasopharyngeal carcinoma

Mouse (Murine) Chromosome 2 Open Reading Frame 40 (C2orf40) interaction partners

  1. proteolytic cleavage by furin (show FURIN Proteins) is a posttranslational requirement for proaugurin to suppress cell proliferation

  2. identified esophageal cancer-related gene 4 (Ecrg4) as a senescence inducer with implications for the senescence-like state of postmitotic cells in the aging brain.

  3. ECRG4 level in differentiated chondrocytes is decreased during hypertrophic maturation

Chromosome 2 Open Reading Frame 40 (C2orf40) Protein Profile

Protein Summary

Probable hormone that may induce senescence of oligodendrocyte and neural precursor cells, characterized by G1 arrest, RB1 dephosphorylation and accelerated CCND1 and CCND3 proteasomal degradation.

Gene names and symbols associated with C2orf40

  • esophageal cancer related gene 4 protein (LOC100345571)
  • chromosome 2 open reading frame 40 (C2orf40)
  • chromosome 11 open reading frame, human C2orf40 (C11H2orf40)
  • chromosome 2 open reading frame 40 (c2orf40)
  • RIKEN cDNA 1500015O10 gene (1500015O10Rik)
  • similar to RIKEN cDNA 1500015O10 (RGD1305645)
  • Ecrg4 protein
  • ecrg4-A protein

Protein level used designations for C2orf40

esophageal cancer related gene 4 protein , augurin , esophageal cancer-related gene 4 protein , UPF0689 protein C2orf40 homolog , esophageal cancer-related gene 4 protein homolog

GENE ID SPECIES
100345571 Oryctolagus cuniculus
713611 Macaca mulatta
515133 Bos taurus
84417 Homo sapiens
373779 Xenopus laevis
78896 Mus musculus
363225 Rattus norvegicus
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