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Chromosome 4 Open Reading Frame 49 Proteins (C4orf49)

Plays a role in the trafficking of mitochondria along microtubules. Additionally we are shipping Chromosome 4 Open Reading Frame 49 Antibodies (24) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
C4orf49 67749 Q8VI64
C4orf49 84709 Q8TDB4
Rat C4orf49 C4orf49 689931  
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Top Chromosome 4 Open Reading Frame 49 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details

C4orf49 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human ,
,

More Proteins for Chromosome 4 Open Reading Frame 49 (C4orf49) Interaction Partners

Mouse (Murine) Chromosome 4 Open Reading Frame 49 (C4orf49) interaction partners

  1. The ratio of motile mitochondria was remarkably decreased in the axons of MGARP-overexpressing cells.

  2. These results indicate that HUMMR does not play a key role in mitochondrial dysfunction in the APP (show APP Proteins)/PS1 (show PSEN1 Proteins) double transgenic Alzheimer disease mouse

  3. MGARP participates in hormone biosynthesis while being under the regulation of the hormones derived from the hypothalamic-pituitary-gonadal axis.

  4. Results identify a mitochondria-localized glutamic acid-rich protein (MGARP/OSAP) as one of the highly expressed proteins in retina [MGARP].

  5. HUMMR (Hypoxia Upregulated Mitochondrial Movement Regulator) is induced by HIF-1 and regulates mitochondrial distribution and movement in neurons during hypoxia

  6. OSAP is prominently expressed in steroidogenic tissues; results suggest that OSAP is involved in steroidogenesis, potentially through its ability to maintain mitochondrial abundance and morphology

Human Chromosome 4 Open Reading Frame 49 (C4orf49) interaction partners

  1. The present study identified a proximal core sequence in the MGARP promoter that is composed of two enriched Sp1 (show PSG1 Proteins) binding motifs and established Sp1 (show PSG1 Proteins) as one major MGARP transactivator.

  2. Results identify a mitochondria-localized glutamic acid-rich protein (MGARP/OSAP) as one of the highly expressed proteins in retina [MGARP].

  3. Results identify a novel mitochondria protein, hypoxia up-regulated mitochondrial movement regulator (HUMMR), which is expressed in neurons and is markedly induced by hypoxia-inducible factor 1 alpha (HIF-1alpha (show HIF1A Proteins)).

  4. OSAP is prominently expressed in steroidogenic tissues; results suggest that OSAP is involved in steroidogenesis, potentially through its ability to maintain mitochondrial abundance and morphology

Chromosome 4 Open Reading Frame 49 (C4orf49) Protein Profile

Protein Summary

Plays a role in the trafficking of mitochondria along microtubules. Regulates the kinesin-mediated axonal transport of mitochondria to nerve terminals along microtubules during hypoxia. Participates in the translocation of TRAK2/GRIF1 from the cytoplasm to the mitochondrion. Also plays a role in steroidogenesis through maintenance of mitochondrial abundance and morphology (By similarity).

Gene names and symbols associated with C4orf49

  • mitochondria localized glutamic acid rich protein (Mgarp)
  • mitochondria-localized glutamic acid-rich protein (MGARP)
  • mitochondria-localized glutamic acid-rich protein (Mgarp)
  • 4930583H14Rik protein
  • AI195347 protein
  • C4orf49 protein
  • CESP-1 protein
  • HUMMR protein
  • OSAP protein
  • Qsap protein

Protein level used designations for C4orf49

corneal endothelium-specific protein 1 , hypoxia up-regulated mitochondrial movement regulator protein , mitochondria-localized glutamic acid-rich protein , ovary-specific acidic protein , protein MGARP , hypoxia up-regulated mitochondrial movement regulator

GENE ID SPECIES
67749 Mus musculus
84709 Homo sapiens
689931 Rattus norvegicus
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