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Chromosome 6 Open Reading Frame 25 Proteins (C6orf25)

C6orf25 is a member of the immunoglobulin (Ig) superfamily and is located in the major histocompatibility complex (MHC) class III region. Additionally we are shipping C6orf25 Antibodies (31) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse C6orf25 C6orf25 106722  
C6orf25 80739 O95866
Rat C6orf25 C6orf25 406865 Q6MG59
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Top C6orf25 Proteins at

Showing 3 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 Days
HOST_Human Cells Human Fc Tag 100 μg Log in to see 16 Days
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days

C6orf25 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, , ,

More Proteins for Chromosome 6 Open Reading Frame 25 (C6orf25) Interaction Partners

Mouse (Murine) Chromosome 6 Open Reading Frame 25 (C6orf25) interaction partners

  1. these findings establish G6b-B as a major inhibitory receptor regulating megakaryocyte activation, function, and platelet production.

Human Chromosome 6 Open Reading Frame 25 (C6orf25) interaction partners

  1. G6B seems to act through an autosomal recessive mode of disease transmission in this family and regarded as the gene responsible for the observed hematological disorder.

  2. Heparin might modulate the interaction of G6b with its as yet unidentified protein ligand

  3. G6B represents a novel inhibitory receptor found on the surface of platelets

  4. G6b-B expression is highly restricted to peripheral CD4 (show CD4 Proteins)+ T cells and up-regulated by the IL-4 (show IL4 Proteins)-induced STAT6 (show STAT6 Proteins) pathway, suggesting that G6b-B is involved in regulation of the immune response by CD4 (show CD4 Proteins)+ T cell-mediated and IL-4 (show IL4 Proteins) induced regulatory mechanisms.

  5. G6b-B inhibits constitutive and agonist-induced signaling by glycoprotein VI and CLEC-2 (show CLEC1B Proteins).

C6orf25 Protein Profile

Protein Summary

This gene is a member of the immunoglobulin (Ig) superfamily and is located in the major histocompatibility complex (MHC) class III region. The protein encoded by this gene is a glycosylated, plasma membrane-bound cell surface receptor, but soluble isoforms encoded by some transcript variants have been found in the endoplasmic reticulum and Golgi before being secreted. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with C6orf25

  • expressed sequence AU023871 (AU023871)
  • G6B protein (G6b)
  • G6B protein (LOC745085)
  • chromosome 23 open reading frame, human C6orf25 (C23H6orf25)
  • chromosome 6 open reading frame 25 (C6orf25)
  • G6b protein (G6b)
  • C6orf25 protein
  • G6B protein
  • LOC745085 protein
  • NG31 protein

Protein level used designations for C6orf25

G6b protein , ITIM-receptor G6b-B , G6B protein , protein G6b , immunoglobulin receptor

106722 Mus musculus
114763 Mus musculus
745085 Pan troglodytes
617577 Bos taurus
80739 Homo sapiens
406865 Rattus norvegicus
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