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Chromosome 7 Open Reading Frame 27 Proteins (C7orf27)

The protein encoded by this ubiquitously expressed gene interacts with the tumor suppressing BRCA1 (breast cancer 1) protein and and the ATM (ataxia telangiectasia mutated) protein. Additionally we are shipping BAAT1 Antibodies (12) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
C7orf27 221927 Q6PJG6
C7orf27 231841 Q8C3R1
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Top BAAT1 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

C7orf27 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Chromosome 7 Open Reading Frame 27 (C7orf27) Interaction Partners

Human Chromosome 7 Open Reading Frame 27 (C7orf27) interaction partners

  1. We conclude that BRAT1 should be added to the growing list of genes related to early-onset severe encephalopathy with epilepsy.

  2. Our results further support that mutations of BRAT1 could lead to epileptic encephalopathy.

  3. Ndfip1 (show NDFIP1 Proteins) is required during stress for ubiquitinating and trafficking BRAT1 into the nucleus.

  4. Findings suggest novel roles of BRAT1 in cell proliferation and mitochondrial functions.

  5. Data on crystal structure of BRCA1 binding with phosphopeptides suggest that C-terminal domain of BRCA1 interacts with BAAT1 and ATRIP (show ATRIP Proteins) with preferences for specific side chains; in BAAT1, phospho-Ser269 and Phe272 are the main interacting residues.

  6. Study identified sequence variants in the known disease-causing genes SLC6A3 (show SLC6A3 Proteins) and FLVCR1 (show FLVCR1 Proteins), and present evidence to strongly support the pathogenicity of variants identified in TUBGCP6, BRAT1, SNIP1 (show SNIP1 Proteins), CRADD (show CRADD Proteins), and HARS (show HARS Proteins).

Mouse (Murine) Chromosome 7 Open Reading Frame 27 (C7orf27) interaction partners

  1. Ndfip1 (show NDFIP1 Proteins) is required during stress for ubiquitinating and trafficking BRAT1 into the nucleus.

BAAT1 (C7orf27) Protein Profile

Protein Summary

The protein encoded by this ubiquitously expressed gene interacts with the tumor suppressing BRCA1 (breast cancer 1) protein and and the ATM (ataxia telangiectasia mutated) protein. ATM is thought to be a master controller of cell cycle checkpoint signalling pathways that are required for cellular responses to DNA damage such as double-strand breaks that are induced by ionizing radiation and complexes with BRCA1 in the multi-protein complex BASC (BRAC1-associated genome surveillance complex). The protein encoded by this gene is thought to play a role in the DNA damage pathway regulated by BRCA1 and ATM.

Gene names and symbols associated with C7orf27

  • BRCA1-associated ATM activator 1 (BRAT1)
  • BRCA1-associated ATM activator 1 (Brat1)
  • BRCA1-associated ATM activator 1 (brat1)
  • AA881470 protein
  • baat1 protein
  • C7orf27 protein
  • RMFSL protein
  • zgc:136845 protein

Protein level used designations for C7orf27

BRCA1-associated protein required for ATM activation protein 1 , HEAT repeat-containing protein C7orf27 , HEAT repeat-containing protein C7orf27 homolog

GENE ID SPECIES
769893 Gallus gallus
221927 Homo sapiens
231841 Mus musculus
678547 Danio rerio
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