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C8orf4 encodes a member of the vitamin B12-binding protein family. Additionally we are shipping C8orf4 Antibodies (24) and many more products for this protein.
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The variant rs526934 from the TCN1 (show TCN1 Proteins) gene was associated with an increased risk of developing gastric cancer.
Decreased capacity of fibrotic lung fibroblasts to up-regulate COX-2 expression and COX-2-derived PGE2 synthesis is due to an indirect epigenetic mechanism involving hypermethylation of the transcriptional regulator, c8orf4.
C8orf4 negatively regulates the self-renewal of liver CSCs via suppression of NOTCH2 (show NOTCH2 Proteins) signalling
the high expression of TC1 was common in oral tongue squamous cell carcinomas and correlated with the expression of b-catenin and cyclin D1 (show CCND1 Proteins) and the progression of oral tongue squamous cell carcinomas
TC-1 overexpression promotes cell proliferation in human non-small cell lung cancer that can be inhibited by PD173074.
TC-1 expression is associated with aggressive biologic behavior in lung cancer and might coordinate with the Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) pathway as a positive upstream regulator that induces these behaviors.
TCN1 (show TCN1 Proteins) gene expression implicates disease progression in patient with middle ear cholesteatoma.
The higher expression of TC-1 in ovarian compared to colorectal adenocarcinomas suggests its potential use as a marker
The SNP rs10958605 in the C8orf4 gene had the smallest p value in analyses of the motor outcome.
A significant association was found between the copy-number deletions of C8orf4 and the risk of hematological malignancies.
This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This protein is a major constituent of secondary granules in neutrophils and facilitates the transport of cobalamin into cells.
human thyroid cancer 1
, thyroid cancer protein 1
, uncharacterized protein C8orf4
, chromosome 8 open reading frame 4