Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Additionally we are shipping Chymotrypsin-Like Elastase Family, Member 1 Antibodies (51) and Chymotrypsin-Like Elastase Family, Member 1 Kits (21) and many more products for this protein.
Showing 10 out of 14 products:
insights into the PPE and HNE (show ELANE Proteins) inhibition
Here, we studied the priming of SARS (show SARS Proteins)-CoV S by elastase and show an important role for residue Thr (show TRH Proteins)(795) in the S2 domain.
comparison of x-ray structures of alpha1PI complexes with trypsin, PPE, and human neutrophil elastase (show ELANE Proteins)
the oxygen of the oxopropyl group of the inhibitor is present as an oxygen anion rather than a hydroxyl group, supporting the role of the "oxyanion hole" in stabilizing the tetrahedral intermediate in ELS1 catalysis
The stretch-dependent expression and binding kinetics of Cela1 indicate an important role in stretch-dependent remodeling of the peripheral lung during development and regeneration.
defines the temporal-spatial pattern of elastin (show ELN Proteins) remodeling during lung development, demonstrates an association of this remodeling with chymotrypsin-like elastase 1
Glucocorticoid receptor (show NR3C1 Proteins)-null lungs included Chi3l3 (show CHI3L3 Proteins) (11-fold, P < 0.05), a macrophage inflammatory response gene and Ela1 (9.4-fold, P < 0.05), an extracellular matrix remodeling enzyme.
A heterozygous frameshift variant c.419delC in exons of the CELA1 gene identified in all punctate palmoplantar keratoderma patients.
variants affecting amino-acid position 241 in CELA3A and CELA3B (show ELA3B Proteins) are not associated with chronic pancreatitis, indicating that changes in complex formation between proelastases and procarboxypeptidases do not alter pancreatitis risk.
Inverse association of HbA1c with faecal elastase 1 in people without diabetes suggests that pancreatic exocrine dysfunction might be an early disturbance that develops in parallel with hyperglycemia.
The results of the study suggest that the levels of apelin (show APLN Proteins), TNF-alpha (show TNF Proteins) and elastase-1 are important diagnostic markers of CP in patients with type 2 diabetes mellitus.
Results indicate that the extract of the mycelium of Tricholoma matsutake decreased elastase activity in a dose-dependent manner and reduced the levels of matrix metalloproteinase 1 (MMP-1 (show MMP1 Proteins)).
Mutant genes (CELA1, HSPG2, and KCNK5) in Balkan endemic nephropathy patients encode proteins involved in basement membrane/extracellular matrix and vascular tone, tightly connected to process of angiogenesis.
A low value of faecal elastase-1, indicating reduced exocrine pancrease secretion, is strongly correlated with a poor survival in advanced pancreatic cancer.
Hypermethylation of ELA3B (show ELA3B Proteins) gene promoter were associated with pancreatic cancer.
pancreatic elastase induced proinflammatory effects are mediated by TLR4 (show TLR4 Proteins) and NF-kappaB (show NFKB1 Proteins) in human myeloid cells
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3B has little elastolytic activity. Like most of the human elastases, elastase 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays.
chymotrypsin-like elastase family, member 1
, pancreatic elastase 1
, chymotrypsin-like elastase family member 1
, pancreatic elastase I
, elastase 1, pancreatic
, elastase I
, cholesterol-binding pancreatic protease
, chymotrypsin-like elastase family member 3B
, elastase 1
, elastase 3B, pancreatic
, elastase IIIB
, fecal elastase 1
, pancreatic endopeptidase E
, protease E
, proteinase E