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Citron (Rho-Interacting, serine/threonine Kinase 21) Proteins (CIT)

CIT encodes a serine/threonine-protein kinase that functions in cell division. Additionally we are shipping CIT Antibodies (26) and CIT Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat CIT CIT 83620  
Mouse CIT CIT 12704  
CIT 11113 O14578
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Top CIT Proteins at antibodies-online.com

Showing 2 out of 2 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Baculovirus infected Insect Cells Human GST tag   5 μg Log in to see 10 to 12 Days
$365.64
Details

CIT Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

More Proteins for Citron (Rho-Interacting, serine/threonine Kinase 21) (CIT) Interaction Partners

Mouse (Murine) Citron (Rho-Interacting, serine/threonine Kinase 21) (CIT) interaction partners

  1. Data propose that the CC-domain-mediated translocation and actions of Citron-K ensure proper stabilization of the midbody structure during the transition from constriction to abscission.

  2. p27 (show CDKN1B Proteins) has a role in cytokinesis via the regulation of citron-K activity

  3. CITRON has a role in proliferation of hepatocellular carcinoma cells

  4. Data report that Discs large 5 (Dlg5), a member of the MAGUK family, is an interactor of CitK required for CitK polarization.

  5. Citron-K has a distinct cell cycle-dependent expression pattern and cellular localization as a downstream target of Rho-GTPase (show RACGAP1 Proteins) and functions in the control of G(2)/M transition in the hepatocyte cell cycle

  6. Quantitative analysis of citron kinase in cerebral cortex of knockout mice demonstrates that this molecule is involved in differentially regulating the morphology of the dendritic compartment in corticocollicular projecting pyramidal neurons.

  7. These results suggest that the TTC3-RhoA (show RHOA Proteins)-CIT-K pathway could be a crucial determinant of in vivo neuronal development, whose hyperactivity may result in detrimental effects on the normal differentiation program.

  8. Lack of citron kinase gene in newborn mice profoundly alters barrelfield cortex cell morphology and number.

Human Citron (Rho-Interacting, serine/threonine Kinase 21) (CIT) interaction partners

  1. The TPC1 was shown to interact with citron kinase, with TPC1 overexpression affecting RhoA activity and myosin light chain phosphorylation levels in cytokinesis.

  2. Data propose that the CC-domain-mediated translocation and actions of Citron-K ensure proper stabilization of the midbody structure during the transition from constriction to abscission.

  3. High CIT expression is associated with prostate cancer.

  4. p27 (show PAK2 Proteins) has a role in cytokinesis via the regulation of citron-K activity

  5. CIT-K is a crucial abscission regulator that may promote midbody stability through active RhoA (show RHOA Proteins) and anillin (show ANLN Proteins).

  6. Hrs inhibits HIV-1 production by inhibiting citron kinase-mediated exocytosis.

  7. CITRON has a role in proliferation of hepatocellular carcinoma cells

  8. Evidence of statistical epistasis between DISC1 (show DISC1 Proteins), CIT and NDEL1 (show NDEL1 Proteins) impacting risk for schizophrenia: biological validation with functional neuroimaging.

  9. Citron-K has a distinct cell cycle-dependent expression pattern and cellular localization as a downstream target of Rho-GTPase (show RACGAP1 Proteins) and functions in the control of G(2)/M transition in the hepatocyte cell cycle

  10. During cytokinesis, the localization of KIF14 and citron kinase to the central spindle and midbody is codependent, and they form a complex depending on the activation state of citron kinase.

CIT Protein Profile

Protein Summary

This gene encodes a serine/threonine-protein kinase that functions in cell division. Together with the kinesin KIF14, this protein localizes to the central spindle and midbody, and functions to promote efficient cytokinesis. This protein is involved in central nervous system development. Polymorphisms in this gene are associated with bipolar disorder and risk for schizophrenia. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with CIT

  • citron (rho-interacting, serine/threonine kinase 21) (Cit)
  • citron (rho-interacting, serine/threonine kinase 21) (CIT)
  • citron (rho-interacting, serine/threonine kinase 21) (cit)
  • citron (Cit)
  • C030025P15Rik protein
  • CIT protein
  • Cit-k protein
  • CRIK protein
  • CRIK-SK protein
  • STK21 protein
  • xcit protein

Protein level used designations for CIT

citron Rho-interacting kinase , citron kinase , citron-K kinase , postsynaptic density protein (citron) , citron (rho-interacting, serine/threonine kinase 21) , citron-N , rho-interacting, serine/threonine-protein kinase 21 , serine/threonine-protein kinase 21

GENE ID SPECIES
83620 Rattus norvegicus
416984 Gallus gallus
452298 Pan troglodytes
695846 Macaca mulatta
786852 Bos taurus
100050621 Equus caballus
100083347 Ornithorhynchus anatinus
100145758 Xenopus (Silurana) tropicalis
100153706 Sus scrofa
100348177 Oryctolagus cuniculus
100544730 Meleagris gallopavo
100553665 Anolis carolinensis
12704 Mus musculus
11113 Homo sapiens
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