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CIITA Proteins

(Class II, Major Histocompatibility Complex, Transactivator (CIITA))
This gene encodes a protein with an acidic transcriptional activation domain, 4 LRRs (leucine-rich repeats) and a GTP binding domain. The protein is located in the nucleus and acts as a positive regulator of class II major histocompatibility complex gene transcription, and is referred to as the 'master control factor' for the expression of these genes. The protein also binds GTP and uses GTP binding to facilitate its own transport into the nucleus. Once in the nucleus it does not bind DNA but rather uses an intrinsic acetyltransferase (AT) activity to act in a coactivator-like fashion. Mutations in this gene have been associated with bare lymphocyte syndrome type II (also known as hereditary MHC class II deficiency or HLA class II-deficient combined immunodeficiency), increased susceptibility to rheumatoid arthritis, multiple sclerosis, and possibly myocardial infarction. [provided by RefSeq, Jul 2008].
CIITA Protein (AA 39-148) (GST tag) CIITA Protein (AA 39-148) (GST tag) CIITA Protein (AA 39-148) (GST tag) (ABIN1349483)

CIITA Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP

CIITA Protein (AA 1-1130) (His tag) CIITA Protein (AA 1-1130) (His tag) CIITA Protein (AA 1-1130) (His tag) (ABIN3090387)

Crystallography grade CIITA Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS

CIITA Protein (AA 1-1155) (His tag) CIITA Protein (AA 1-1155) (His tag) CIITA Protein (AA 1-1155) (His tag) (ABIN3134669)

Crystallography grade CIITA Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS

CIITA Proteins by Grade

Find CIITA Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

CIITA Proteins by Origin

Find CIITA Proteins for a variety of species such as anti-Human CIITA, anti-Mouse CIITA. The species listed below are among those available. Click on a link to go to the corresponding products.

CIITA Proteins by Source

Here you will find CIITA Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

CIITA Proteins by Protein Type

Here you can find CIITA Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

CIITA Proteins by Application

Find CIITA Proteins validated for a specific application such as ELISA, WB, SDS, Crys. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular CIITA Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349483
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3090387
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3134669
Quantity 1 mg
Datasheet Datasheet

Aliases for CIITA Proteins

class II, major histocompatibility complex, transactivator (CIITA) Proteins
class II major histocompatibility complex transactivator (CIITA) Proteins
MHC class II transactivator (LOC710761) Proteins
class II, major histocompatibility complex, transactivator (ciita) Proteins
MHC class II transactivator (LOC100443575) Proteins
class II transactivator (Ciita) Proteins
MHC class II transactivator (LOC100736732) Proteins
class II, major histocompatibility complex, transactivator (Ciita) Proteins
C2ta Proteins
C2TA Proteins
CIITA Proteins
CIITAIV Proteins
EG669998 Proteins
Gm9475 Proteins
MHC2TA Proteins
Mhc2ta Proteins
NLRA Proteins
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