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Claudin 11 Proteins (CLDN11)

CLDN11 encodes a member of the claudin family. Additionally we are shipping Claudin 11 Antibodies (69) and Claudin 11 Kits (33) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CLDN11 5010 O75508
CLDN11 18417 Q60771
Rat CLDN11 CLDN11 84588  
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Top Claudin 11 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Human Cells Human Fc Tag 100 μg Log in to see 16 Days
$437.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

CLDN11 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for Claudin 11 (CLDN11) Interaction Partners

Human Claudin 11 (CLDN11) interaction partners

  1. the expression of miR (show MLXIP Proteins)-99b was inversely correlated with CLDN11 levels . These findings suggest that a high level of miR (show MLXIP Proteins)-99b expression is an independent prognostic factor and correlates with poor survival of patients with Hepatocellular carcinoma (HCC (show FAM126A Proteins))

  2. CLDN11 is an epigenetic biomarker for malignancy in dysplastic nevus and melanoma.

  3. these data suggest that cancer cells may induce CLDN11 overexpression and subsequent collective migration of peritumoral CAFs (show TBX1 Proteins) via TGF-beta (show TGFB1 Proteins) secretion.

  4. The expression of claudin-11 was up regulated in gastric cancer tissue.

  5. The spatial organization of claudin-11 and connexin-43 (show GJA1 Proteins) is altered in men with primary seminiferous tubule failure.

  6. disorganization of claudin-11 expression in Sertoli cells might be one of the factors involved in the impairment of spermatogenesis.

  7. Treatment with 3-deazaneplanocin A, an inhibitor of H3K27 methyltransferase, attenuated CLDN11 induction by serum stimulation in parallel with sustained miR (show MLXIP Proteins)-1275 expression

  8. claudin-11 may have a role in preventing cancer progression and may serve as a therapeutic target in reducing metastasis

  9. late spermatogenic wave may negatively regulate claudin-11 gene activation and the subcellular localization of claudin-11 in Sertoli cells, thus altering the blood testis barrier in the human testis

  10. hypermethylation of CLDN11, leading to downregulated expression, contributes to gastric carcinogenesis by increasing cellular motility and invasiveness

Mouse (Murine) Claudin 11 (CLDN11) interaction partners

  1. Results show that the primary function of claudin-11 is to provide a barrier that impedes the diffusion of material through the intramyelinic compartment

  2. The present study provides the first evidence that DPT (show DPT Proteins) may be a novel effector of cadmium chloride, highlighting the significant role of DPT (show DPT Proteins) in the regulation of claudin-11 expression

  3. Local radiation-induced testicular oxidative stress can elevate the expression of claudin-11 in the testis tissue.

  4. Peptide octamers to modify the course of relapsing experimental autoimmune encephalomyelitis in SJL mice immunized with an oliogodendrocyte-specific protein peptide (OSP 55-71).

  5. Spermatogenesis in all founder mice harboring two copies of the endogenous Cldn11 gene was normal. The promoter/enhancer of the transgene, upstream of exon 1 of the Cldn11 gene, is sufficient to rescue azoospermia in Cldn11-null mice.

  6. we identified Cldn1 (show CLDN1 Proteins), Cldn2 (show CLDN2 Proteins) and Cldn11 as genes that discriminate between diverse types of M2 macrophages

  7. Cldn11(-/-) Sertoli cells exhibit a unique phenotype whereby loss of tight junction integrity results in loss of the epithelial phenotype.

  8. claudin-11 has a role in forming tight junctions in stria vascularis required for hearing through generation of endocochlear potential

  9. These data demonstrate that OSP/claudin-11 and PLP (show C3 Proteins) have essential structural functions in maintaining normal compact myelin and there is redundancy in their functions.

  10. K(V)3.1 K(+) current accounts for significant component of total K(+) current in oligodendrocyte lineage and, in association with OSP/claudin-11, plays significant role in OPC proliferation and migration and myelination of axons.

Claudin 11 (CLDN11) Protein Profile

Protein Summary

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is a major component of central nervous system (CNS) myelin and plays an important role in regulating proliferation and migration of oligodendrocytes. Mouse studies showed that the gene deficiency results in deafness and loss of the Sertoli cell epithelial phenotype in the testis. This protein is a tight junction protein at the human blood-testis barrier (BTB), and the BTB disruption is related to a dysfunction of this gene. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with Claudin 11 Proteins (CLDN11)

  • claudin 11b (cldn11b)
  • claudin 11 (CLDN11)
  • claudin 11 (Cldn11)
  • claudin 11-like (LOC100352273)
  • Claudin-11 protein
  • Claudin11 protein
  • CLDN11 protein
  • DKFZp459H2322 protein
  • fb97c11 protein
  • Osp protein
  • Otm protein
  • wu:fb97c11 protein

Protein level used designations for Claudin 11 Proteins (CLDN11)

claudin 11 , claudin 11 (oligodendrocyte transmembrane protein) , claudin-11 , oligodendrocyte transmembrane protein , oligodendrocyte-specific protein

GENE ID SPECIES
81592 Danio rerio
460846 Pan troglodytes
696363 Macaca mulatta
100171687 Pongo abelii
5010 Homo sapiens
18417 Mus musculus
84588 Rattus norvegicus
424990 Gallus gallus
488160 Canis lupus familiaris
100302016 Sus scrofa
508268 Bos taurus
100732534 Cavia porcellus
101113649 Ovis aries
100352273 Oryctolagus cuniculus
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