You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Claudin 16 (CLDN16) Antibodies

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. Additionally we are shipping Claudin 16 Kits (23) and Claudin 16 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CLDN16 10686 Q9Y5I7
CLDN16 114141 Q925N4
CLDN16 155268 Q91Y55
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-Claudin 16 Antibodies at antibodies-online.com

Showing 10 out of 52 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB CLDN16 Antibody (N-term) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. CLDN16 antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human Kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CLDN16 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB CLDN16 Antibody (N-term) (ABIN654394) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details
Human Rabbit Un-conjugated IHC (fro), IF   100 μg Log in to see 8 to 10 Days
$837.83
Details
Human Mouse Un-conjugated ELISA, WB Western Blot analysis of CLDN16 expression in transfected 293T cell line by CLDN16 monoclonal antibody (M02), clone 1F2.Lane 1: CLDN16 transfected lysate(33.8 KDa).Lane 2: Non-transfected lysate. Detection limit for recombinant GST tagged CLDN16 is 0.3 ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated ELISA, WB CLDN16 polyclonal antibody (A01), Lot # 060614JCS1. Western Blot analysis of CLDN16 expression in Daoy. Western Blot detection against Immunogen (34.14 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Alkaline Phosphatase (AP) FACS, IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details

CLDN16 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,
,
,
, , , , , , , , , , , , , ,
Mouse (Murine) ,


, , , , , , , , , , ,
Rat (Rattus) ,


, , , , , , , , , , ,

Top referenced anti-Claudin 16 Antibodies

  1. Human Polyclonal CLDN16 Primary Antibody for EIA, FACS - ABIN951545 : Kuo, Chien, Lin, Chan, Tsai, Chen: Significant elevation of CLDN16 and HAPLN3 gene expression in human breast cancer. in Oncology reports 2010 (PubMed)
    Show all 4 references for ABIN951545

  2. Human Polyclonal CLDN16 Primary Antibody for WB - ABIN2778049 : Müller, Kausalya, Claverie-Martin, Meij, Eggert, Garcia-Nieto, Hunziker: A novel claudin 16 mutation associated with childhood hypercalciuria abolishes binding to ZO-1 and results in lysosomal mistargeting. in American journal of human genetics 2003 (PubMed)
    Show all 3 references for ABIN2778049

More Antibodies against Claudin 16 Interaction Partners

Human Claudin 16 (CLDN16) interaction partners

  1. CLDN16 mutations are associated with familial hypomagnesaemia with hypercalciuria and nephrocalcinosis.

  2. 1,25(OH)2 VitD transcriptionally inhibits renal claudin-16 expression by a mechanism sensitive to CaSR (show CASR Antibodies) and Mg(2 (show MUC7 Antibodies)+).

  3. A novel CLDN16 mutation has been identified in a large consanguineous family with familial hypomagnesaemia with hypercalciuria and nephrocalcinosis.

  4. These results suggest that STX8 (show STX8 Antibodies) mediates the recycling of CLDN16 and constitutes an important component of the CLDN16 trafficking machinery in the kidney.

  5. Six different mutations of CLDN16 were detected (five missense and one nonsense); three of the missense mutations were previously unknown (p.Cys80Tyr, p.Lys183Glu, and p.Gly233Arg).

  6. A novel mutation of CLDN16 gene is responsible for familial hypomagnesaemia in Turkish children.

  7. Claudin-16 plays a role beyond that of an initial metastasis repressor in breast cancer.

  8. Claudin 16 gene revealed homozygosity for the p.K183E(AAA (show APP Antibodies)>GAA (show GAA Antibodies)) C. 547A>G indicating the diagnosis of hypomagnesemia with hypercalciuria and nephrocalcinosis.

  9. Multiple distinct mutations in the CLDN16 and CLDN19 (show CLDN19 Antibodies) genes have been found responsible for familial hypomagnesemia with hypercalciuria and nephrocalcinosis.

  10. Elevated CLDN16 gene expression was suggested to be involved in the development of breast cancer and to be a biomarker and target treatment for breast cancer.

Cow (Bovine) Claudin 16 (CLDN16) interaction partners

  1. Claudin-16 sequences were not usually amplified from a small number of sperm cells (< or =10 cells) but claudin-16 DNA sequences were occasionally detected when a large number of sperm cells (> or =50 cells) were present.

  2. Renal lesions in Japanese Black cattle are not necessarily associated with homozygous deletion of the CL-16 gene.

Mouse (Murine) Claudin 16 (CLDN16) interaction partners

  1. 1,25(OH)2 VitD transcriptionally inhibits renal claudin-16 expression by a mechanism sensitive to CaSR (show CASR Antibodies) and Mg(2 (show MCOLN1 Antibodies)+).

  2. Mg(2 (show MCOLN1 Antibodies)+)-loaded animals displayed hypermagnesemia with increasing urine Mg(2 (show MCOLN1 Antibodies)+)/Ca(2 (show CA2 Antibodies)+) levels paralleled by a decrease in claudin-16 protein and mRNA in the kidney.

  3. data suggest that claudin-16 forms a non-selective paracellular cation channel (show TRPV1 Antibodies), rather than a selective Mg(2 (show MCOLN1 Antibodies)+)/Ca(2 (show CA2 Antibodies)+) channel as previously proposed

  4. Perturbation in salt and acid-base metabolism in CLDN16 knockout mice has its origin in the defective cation permeability selectivity of the thick ascending limb of the nephron.

  5. Insights into driving forces and paracellular permeability from claudin-16 knockdown mouse

  6. Claudin-16 and claudin-19 (show CLDN19 Antibodies) interaction is required for their assembly into tight junctions and for renal reabsorption of magnesium.

Claudin 16 (CLDN16) Antigen Profile

Protein Summary

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is found primarily in the kidneys, specifically in the thick ascending limb of Henle, where it acts as either an intercellular pore or ion concentration sensor to regulate the paracellular resorption of magnesium ions. Defects in this gene are a cause of primary hypomagnesemia, which is characterized by massive renal magnesium wasting with hypomagnesemia and hypercalciuria, resulting in nephrocalcinosis and renal failure. This gene and the CLDN1 gene are clustered on chromosome 3q28.

Gene names and symbols associated with anti-Claudin 16 (CLDN16) Antibodies

  • claudin 16 (CLDN16) antibody
  • claudin 16 (Cldn16) antibody
  • claudin 16 (LOC100356384) antibody
  • claudin-16 antibody
  • CLDN16 antibody
  • HOMG3 antibody
  • Pcln1 antibody

Protein level used designations for anti-Claudin 16 (CLDN16) Antibodies

claudin 16 , PCLN-1 , claudin-16 , hypomagnesemia 3, with hypercalciuria and nephrocalcinosis , paracellin-1 , CL-16 , H59D2a protein

GENE ID SPECIES
429147 Gallus gallus
740268 Pan troglodytes
10686 Homo sapiens
608218 Canis lupus familiaris
100302019 Sus scrofa
282184 Bos taurus
114141 Mus musculus
155268 Rattus norvegicus
100356384 Oryctolagus cuniculus
101105382 Ovis aries
Selected quality suppliers for anti-Claudin 16 (CLDN16) Antibodies
Did you look for something else?