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Cleavage and Polyadenylation Specific Factor 3, 73kDa (CPSF3) ELISA Kits

CPSF3 encodes a member of the metallo-beta-lactamase family. Additionally we are shipping CPSF3 Antibodies (60) and CPSF3 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human CPSF3 CPSF3 51692 Q9UKF6
Anti-Rat CPSF3 CPSF3 298916  
Anti-Mouse CPSF3 CPSF3 54451 Q9QXK7
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More ELISA Kits for CPSF3 Interaction Partners

Human Cleavage and Polyadenylation Specific Factor 3, 73kDa (CPSF3) interaction partners

  1. the molecular mechanism that recruits the CPSF73 endonuclease to histone pre-mRNAs

  2. The data support a model where Star-PAP (show TUT1 ELISA Kits) binds to the pre-mRNA, recruits the CPSF complex to the 3'-end of pre-mRNA and then defines cleavage by CPSF 73 and subsequent polyadenylation of its target mRNAs.

  3. up-regulated by HIV-1 TAT (show TAT ELISA Kits) protein; this could represent a novel mechanism by which HIV increases mRNA processing, causing an increase in both cell and viral gene expression.

  4. crystal structures of human CPSF-73 at 2.1 A resolution, complexed with zinc ions and a sulphate that might mimic the phosphate group of the substrate; CPSF-73 is the pre-mRNA 3'-end-processing endonuclease

  5. this study identifies CPSF-73 as an important regulatory protein that represses the basal transcriptional activity of the HIV-1 LTR promoter

  6. Conserved residues in CPSF-73 and CPSF2 (show CPSF2 ELISA Kits) are required for assembly of the endonuclease activity that cleaves histone pre-mRNAs.

  7. CSR1 (show SCARA3 ELISA Kits) appears to induce cell death through a novel mechanism by hijacking a critical RNA processing enzyme CPSF3.

  8. Degradation of the downstream cleavage product (DCP (show ACE ELISA Kits)) does not depend on the Xrn2 (show XRN2 ELISA Kits) 5' exonuclease (show EXO1 ELISA Kits), suggesting that CPSF-73 degrades the DCP (show ACE ELISA Kits) both in vitro and in vivo.

  9. The tumor suppressor Cdc73 functionally associates with CPSF and CstF 3' mRNA processing factors.

CPSF3 Antigen Profile

Antigen Summary

This gene encodes a member of the metallo-beta-lactamase family. The encoded protein is a 73kDa subunit of the cleavage and polyadenylation specificity factor and functions as an endonuclease that recognizes the pre-mRNA 3'-cleavage site AAUAAA prior to polyadenylation. It also cleaves after the pre-mRNA sequence ACCCA during histone 3'-end pre-mRNA processing.

Gene names and symbols associated with CPSF3

  • cleavage and polyadenylation specific factor 3, 73kDa (CPSF3) antibody
  • cleavage and polyadenylation specific factor 3, 73kDa (cpsf3) antibody
  • cleavage and polyadenylation specificity factor subunit 3 (CpipJ_CPIJ011955) antibody
  • cleavage and polyadenylation specificity factor subunit 3 (CMU_024380) antibody
  • cleavage and polyadenylation specificity factor subunit 3 (PITG_07110) antibody
  • cleavage and polyadenylation specific factor 3 (cpsf3) antibody
  • cleavage and polyadenylation specific factor 3, 73kDa (LOC100354833) antibody
  • cleavage and polyadenylation specific factor 3, 73kDa (Cpsf3) antibody
  • cleavage and polyadenylation specificity factor 3 (Cpsf3) antibody
  • CPSF-73 antibody
  • CPSF3 antibody
  • CPSF73 antibody
  • si:dkey-81b15.1 antibody
  • wu:fc32f10 antibody
  • zgc:101655 antibody

Protein level used designations for CPSF3

cleavage and polyadenylation specificity factor 73 kDa subunit , cleavage and polyadenylation specificity factor subunit 3 , cleavage and polyadenylation specificity factor 3 , cleavage and polyadenylation specific factor 3, 73kDa , cleavage and polyadenylation specificity factor subunit 3-like , mRNA 3'-end-processing endonuclease CPSF-73 , CPSF 73 kDa subunit

GENE ID SPECIES
459017 Pan troglodytes
448456 Xenopus (Silurana) tropicalis
694036 Macaca mulatta
421929 Gallus gallus
100174072 Pongo abelii
6044555 Culex quinquefasciatus
6995165 Cryptosporidium muris RN66
9464071 Phytophthora infestans T30-4
100194853 Salmo salar
100354833 Oryctolagus cuniculus
100407252 Callithrix jacchus
100564303 Anolis carolinensis
100604815 Nomascus leucogenys
324554 Danio rerio
495111 Xenopus laevis
51692 Homo sapiens
482962 Canis lupus familiaris
281712 Bos taurus
298916 Rattus norvegicus
54451 Mus musculus
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