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Coagulation Factor V Proteins (F5)

F5 encodes an essential cofactor of the blood coagulation cascade. Additionally we are shipping Coagulation Factor V Antibodies (112) and Coagulation Factor V Kits (51) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
F5 14067 O88783
F5 2153 P12259
Rat F5 F5 304929  
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Top Coagulation Factor V Proteins at antibodies-online.com

Showing 10 out of 22 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
$792.00
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$816.20
Details
HOST_Escherichia coli (E. coli) Cow His tag,GST tag 100 μg Log in to see 11 to 13 Days
$859.10
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Wild boar His tag   100 μg Log in to see 11 to 13 Days
$492.80
Details
HOST_Human Human Un-conjugated   0.05 mg Log in to see 2 to 3 Days
$407.00
Details
HOST_Escherichia coli (E. coli) Pig Un-conjugated   100 μg Log in to see 9 to 19 Days
$684.50
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 9 to 19 Days
$967.75
Details

F5 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,

More Proteins for Coagulation Factor V (F5) Interaction Partners

Mouse (Murine) Coagulation Factor V (F5) interaction partners

  1. These findings reveal a novel biological function and mechanism of the protein C (show PROC Proteins) pathway in which protein S and the aPC (show APC Proteins)-cleaved form of fV are cofactors for anti-inflammatory cell signaling by aPC (show APC Proteins) in the context of endotoxemia and infection

  2. Mice deficient in LMAN1 exhibit FV and FVIII deficiencies and liver accumulation of alpha1-antitrypsin.

  3. The FVL mutation does not influence coagulation activation, lung inflammation or survival in lethal influenza A.

  4. It suggested that there could be a combination of GLA (show GLA Proteins) deficiency and FVL or other thrombosis-related gene defect in patients with genetic severe early-onset thrombosis.

  5. Data suggest that tissue factor (show F3 Proteins) and factor V induction by LPS (show TLR4 Proteins) may in part accelerate mesangioproliferative glomerulonephritis through activation of factor X and downstream proinflammatory and procoagulant mechanisms.

  6. The source of the FVL leading to accelerated thrombosis appears to be circulating, non-platelet-derived plasma FVL.

  7. FVL has the ability to improve the hemophilia A or B phenotype, but this effect is principally evident at the microcirculation level following a particular vascular injury.

  8. observations demonstrate a synergistic interaction between alpha-galactosidase A (show GLA Proteins) deficiency and Factor V Leiden toward tissue fibrin deposition; concomitant mutations in these genes may increase the penetrance of vascular thrombotic events in humans

  9. Fetal gene defects precipitate platelet-mediated pregnancy failure in factor V Leiden mothers.

  10. The FVL mutation has no effect on the development of secondary tumours of colon cancer in livers of mice.

Human Coagulation Factor V (F5) interaction partners

  1. Factor V (F5) c.1691G>A (Leiden) was present in 0.5% of 400 ischemic stroke patients in Sri (show SRI Proteins) Lanka. F5 mutation was present in a statistically significant number of patients with venous thrombosis (P = .005) compared to those with arterial thrombosis.

  2. The present data showed that FVL, MTHFR (show MTHFR Proteins) polymorphisms also combined with thrombophilic gene mutations have a strong association with recurrent pregnancy loss.

  3. FVL has a modifying effect on PAI-1 (show SERPINE1 Proteins) polymorphism in relation to risk of VTE recurrence.

  4. combination of FVL and MTHFR (show MTHFR Proteins) mutation related to the risk of recurrent fetal death and habitual abortion

  5. Case Report: acquired FV inhibitor that developed in a patient after exposure to human thrombin (show F2 Proteins) used as a hemostatic agent during an otorhinolaryngology surgical procedure.

  6. In the current study Factor V Leiden, prothrombin (show F2 Proteins) G20210A, and thrombospondin-1 (show THBS1 Proteins) polymorphisms showed no association with severity of hepatic fibrosis.

  7. Chromosomal abnormalities and abnormalities in the genes related to thrombophilia such as FVL, MTHFR (show MTHFR Proteins) and PTm mutations may be considered as risk factors for RM [recurrent miscarriage]

  8. Given the essential role of platelet-derived factor Va in clot (show TXNDC17 Proteins) formation, understanding the cellular and molecular mechanisms that regulate how platelets acquire this molecule will be important for the treatment of excessive bleeding or clotting

  9. the diagnosis of an 'unaffected' foetus was offered. The child was subsequently followed up after delivery and was found to be normal for factor V levels with a normal genotype

  10. Data (including data from case-control, genetic association studies) suggest that Factor V mutation Leiden is associated with significant genetic predisposition for venous thromboembolism (not thrombophilia) in pregnancy. [META-ANALYSIS, REVIEW]

Cow (Bovine) Coagulation Factor V (F5) interaction partners

  1. Data suggest factor Xa (FXa (show F10 Proteins)) and factor Va (FVa) compete to bind FXa (show F10 Proteins) on both PS model membranes and microparticles from activated platelets; this competition between dimerization/prothrombinase (show FGL2 Proteins) complex formation appears to regulate blood coagulation.

Coagulation Factor V (F5) Protein Profile

Protein Summary

This gene encodes an essential cofactor of the blood coagulation cascade. This factor circulates in plasma, and is converted to the active form by the release of the activation peptide by thrombin during coagulation. This generates a heavy chain and a light chain which are held together by calcium ions. The activated protein is a cofactor that participates with activated coagulation factor X to activate prothrombin to thrombin. Defects in this gene result in either an autosomal recessive hemorrhagic diathesis or an autosomal dominant form of thrombophilia, which is known as activated protein C resistance.

Gene names and symbols associated with Coagulation Factor V Proteins (F5)

  • coagulation factor V (LOC100534566)
  • coagulation factor V (F5)
  • coagulation factor V (proaccelerin, labile factor) (F5)
  • Ac2-120 protein
  • AI173222 protein
  • Cf-5 protein
  • Cf5 protein
  • FVL protein
  • PCCF protein
  • RPRGL1 protein
  • THPH2 protein

Protein level used designations for Coagulation Factor V Proteins (F5)

coagulation factor V , activated protein C cofactor , activated protein c cofactor , coagulation factor V jinjiang A2 domain , factor V Leiden , proaccelerin, labile factor

GENE ID SPECIES
100534566 Oreochromis niloticus
14067 Mus musculus
2153 Homo sapiens
304929 Rattus norvegicus
280687 Bos taurus
100715882 Cavia porcellus
397217 Sus scrofa
100685858 Canis lupus familiaris
101123649 Ovis aries
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