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anti-Coagulation Factor XI (F11) Antibodies

F11 encodes coagulation factor XI of the blood coagulation cascade. Additionally we are shipping Factor XI Kits (42) and Factor XI Proteins (15) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
F11 2160 P03951
Anti-Mouse F11 F11 109821 Q91Y47
F11 290757  
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Top anti-Factor XI Antibodies at antibodies-online.com

Showing 10 out of 64 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Formalin fixed and paraffin embedded human liver tissue stained with F11 Antibody (Center) followed by peroxidase conjugation of the secondary antibody and DAB staining. Western blot analysis of F11 Antibody (Center) in Jurkat cell line lysates (35ug/lane).This demonstrates the F11 antibody detected the F11 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-F11 AntibodyTitration: 1.0 µg/mL  Positive Control: Hela Whole Cell 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB F11 Antibody (Center) (ABIN655515) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated ELISA   100 μg Log in to see 16 Days
$218.90
Details
Human Mouse Un-conjugated EIA, Func, RIA, WB   0.1 mg Log in to see 6 to 8 Days
$286.00
Details
Human Rabbit Un-conjugated ELISA   100 μg Log in to see 16 Days
$163.90
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$365.20
Details
Rat Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$398.20
Details
Human Rabbit Un-conjugated IHC, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Mouse Un-conjugated RIA, ELISA, WB   100 μg Log in to see 8 to 10 Days
$522.50
Details

F11 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Factor XI Antibodies

  1. Human Polyclonal Factor XI Primary Antibody for EIA, WB - ABIN951607 : Wong, Jiang: Apixaban, a direct factor Xa inhibitor, inhibits tissue-factor induced human platelet aggregation in vitro: comparison with direct inhibitors of factor VIIa, XIa and thrombin. in Thrombosis and haemostasis 2010 (PubMed)
    Show all 2 references for ABIN951607

  2. Human Polyclonal Factor XI Primary Antibody for ELISA - ABIN1996325 : Gailani, Smith: Structural and functional features of factor XI. in Journal of thrombosis and haemostasis : JTH 2009 (PubMed)

More Antibodies against Factor XI Interaction Partners

Human Coagulation Factor XI (F11) interaction partners

  1. the co-localization of thrombin (show F2 Antibodies) and factor XI and the resultant efficient activation of FXI requires GPIb alpha (show GP1BA Antibodies)

  2. factor XI is localized to GPIb in membrane rafts and that this association is important for promoting the activation of factor XI by thrombin (show F2 Antibodies) on the platelet surface

  3. Factor XI and factor XII (show F12 Antibodies) activities were significantly higher in patients with slow coronary flow than in controls, and could be associated with enhanced procoagulant state present in these patients.

  4. FXI-thrombin (show F2 Antibodies) axis contributes to distal platelet activation and procoagulant microaggregate formation in the blood flow downstream of the site of thrombus formation.

  5. F11 gene variant rs2289252 contributes to inherited forms of deep vein thrombosis incidence in Latvian population.

  6. ROTEM assays failed to distinguish bleeding from non-bleeding patients but could do so between different FXI activity levels and genotypes.

  7. increased activity of FXI may be a potential risk factor for miscarriage; high activity of FXI diagnosed in women with history of miscarriage is not probably caused by the presence of SNPs rs2289252 and rs2036914

  8. Data indicate that the mean factor XI (FXI) was not significantly different in laboratories using the same method on both exercises, suggesting good intralaboratory precision over time.

  9. Identification of a novel c.290G>A mutation in the F11 gene that is associated with mild Factor XI deficiency in a Dutch Caucasian family.

  10. In whites, the FXI variant was associated with both factor XI concentration and venous thromboembolism (VTE) incidence (1.15-fold greater incidence of VTE per risk allele), whereas In African-Americans, these associations were absent.

Mouse (Murine) Coagulation Factor XI (F11) interaction partners

  1. Thrombin (show F2 Antibodies)-independent contribution of tissue factor (show F3 Antibodies) to inflammation and cardiac hypertrophy in a mouse model of sickle cell disease.

  2. FXI deprivation was shown to slow down atherogenesis in Apoe (show APOE Antibodies) knockout mice.

  3. anion-binding sites on FXIa that are required for expression of heparin's cofactor activity during protease inhibition by antithrombin (show SERPINC1 Antibodies) are also required for expression of polyP cofactor activity during FXI activation

  4. Data conclude that within the mouse F11, Klkb1 (show KLKB1 Antibodies), Cyp4v3 (show CYP4V2 Antibodies) gene cluster, F11 and Cyp4v3 (show CYP4V2 Antibodies) frequently display striking parallel transcriptional responses suggesting the presence of shared regulatory elements.

  5. Studies indicate that targeting factor XI (FXI) by knocking out the gene prevents arterial and vein thrombosis.

  6. Protective roles for fibrin, tissue factor (show F3 Antibodies), plasminogen activator inhibitor-1 (show SERPINE1 Antibodies), and thrombin activatable fibrinolysis inhibitor (show CPB2 Antibodies), but not factor XI, during defense against the gram-negative bacterium Yersinia enterocolitica.

  7. fXI and fXII (show F12 Antibodies) contribute to thrombus formation even when factor VIIa/tissue factor (show F3 Antibodies) initiates thrombosis.

  8. Gene targeting of tissue factor (show F3 Antibodies), factor X, and factor VII (show TH Antibodies) in mice: their involvement in embryonic development

  9. FXI is essential for thrombus formation following FeCl3-induced injury of the carotid artery in the mouse.

  10. FIX and FXI deficiency cause similar effects in the carotid artery injury model

Cow (Bovine) Coagulation Factor XI (F11) interaction partners

  1. Sequence analysis of the bovine coagulation factor XI (F11) gene revealed an unusually high number of non-synonymous mutations. However, none of the mutations in the F11 gene were concordant with Bovine neonatal pancytopenia status.

  2. Insertion of 15 nucleotides in the F11 gene is the causative mutation for factor XI deficiency in Japanese black cattle.

  3. The molecular basis of coagulopathy has been recognized in Holstein cattle as a 76-bp insertion in the coding region of the FXI gene

Factor XI (F11) Antigen Profile

Protein Summary

This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality.

Gene names and symbols associated with F11

  • coagulation factor XI (F11) antibody
  • coagulation factor XI (CpipJ_CPIJ000593) antibody
  • coagulation factor XI (CpipJ_CPIJ001060) antibody
  • coagulation factor XI (CpipJ_CPIJ002752) antibody
  • coagulation factor XI (CpipJ_CPIJ003631) antibody
  • coagulation factor XI (CpipJ_CPIJ004041) antibody
  • coagulation factor XI (CpipJ_CPIJ004093) antibody
  • 1600027G01Rik antibody
  • AI503996 antibody
  • Cf11 antibody
  • FXI antibody
  • LRRGT00086 antibody

Protein level used designations for F11

coagulation factor XI (plasma thromboplastin antecedent) , platelet coagulation factor XI , coagulation factor XI , coagulation factor XI-like , PTA , plasma thromboplastin antecedent , factor XI , blood coagulation factor XI

GENE ID SPECIES
461643 Pan troglodytes
6031603 Culex quinquefasciatus
6032063 Culex quinquefasciatus
6033946 Culex quinquefasciatus
6035180 Culex quinquefasciatus
6035438 Culex quinquefasciatus
6035567 Culex quinquefasciatus
100443368 Pongo abelii
100468102 Ailuropoda melanoleuca
100594390 Nomascus leucogenys
2160 Homo sapiens
109821 Mus musculus
290757 Rattus norvegicus
100009596 Oryctolagus cuniculus
100715511 Cavia porcellus
407998 Bos taurus
475623 Canis lupus familiaris
422723 Gallus gallus
101116630 Ovis aries
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