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anti-Cofilin1/2 (CFL1/2) Antibodies

The protein encoded by CFL1/2 can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner.

list all antibodies Gene Name GeneID UniProt
CFL1/2 1072 P23528
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Top anti-Cofilin1/2 Antibodies at

Showing 4 out of 5 products:

Catalog No. Reactivity Host Conjugate Application Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF, IHC, WB 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated IHC 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated IHC 50 μg Log in to see 11 to 16 Days
Human Rabbit Un-conjugated IHC, WB 50 μg Log in to see 11 to 16 Days

CFL1/2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human ,

Mouse (Murine) ,

Rat (Rattus)

Top referenced anti-Cofilin1/2 Antibodies

  1. Human Polyclonal CFL1/2 Primary Antibody for IF, IHC - ABIN363074 : Chen, Cizeau, Vande Velde, Park, Bozek, Bolton, Shi, Dubik, Greenberg: Nix and Nip3 form a subfamily of pro-apoptotic mitochondrial proteins. in The Journal of biological chemistry 1999 (PubMed)
    Show all 4 references for ABIN363074

  2. Human Polyclonal CFL1/2 Primary Antibody for IHC - ABIN362442 : Arber, Barbayannis, Hanser, Schneider, Stanyon, Bernard, Caroni: Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase. in Nature 1998 (PubMed)
    Show all 4 references for ABIN362442

More Antibodies against Cofilin1/2 Interaction Partners

Human Cofilin1/2 (CFL1/2) interaction partners

  1. the presence of the actin-severing protein, cofilin (show CFL1 Antibodies), in human sperm, is reported.

  2. Aurora kinase A (show AURKA Antibodies) has a role in inducing papillary thyroid cancer lymph node metastasis by promoting cofilin-1 (show CFL1 Antibodies) activity

  3. analysis of human Cof1, Cof2, and ADF effects on actin filament severing and turnover

  4. Cofilin 1 (show CFL1 Antibodies) activation prevents the defects in axon elongation and guidance induced by extracellular alpha-synuclein (show SNCA Antibodies)

  5. novel roles for actin-depolymerizing factor (show GSN Antibodies) and cofilin-1 (show CFL1 Antibodies) in regulating the remodeling and permeability of epithelial junctions

  6. cofilin1 is involved in hypertensive nephropathy by modulating the nuclear translocation of NF-kappaB (show NFKB1 Antibodies) and the expression of its downstream inflammatory factors in renal tubular epithelial cells

  7. Cofilin-1 (show CFL1 Antibodies) and transgelin (show TAGLN Antibodies) may play roles in the carcinogenesis and development of esophageal squamous cell carcinoma

  8. results demonstrate that in VSMCs mechanical stimulation activates cofilin (show CFL1 Antibodies) by a Nox4 (show NOX4 Antibodies)-dependent mechanism and that this pathway is required for cytoskeleton reorganization and cell reorientation

  9. Cor1B, Cof1 and AIP1 work in concert through a temporally ordered pathway to induce highly efficient severing and disassembly of actin filaments.

  10. the results of the present study suggested that miR (show MLXIP Antibodies)-429 inhibits the migration and invasion of colon cancer cells, partly at least, by mediating the expression of PAK6 (show PAK6 Antibodies), as well as the activity of cofilin (show CFL1 Antibodies) signaling

Cofilin1/2 (CFL1/2) Antigen Profile

Protein Summary

The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.

Gene names and symbols associated with anti-Cofilin1/2 (CFL1/2) Antibodies

  • cofilin 1 (non-muscle) (CFL1) antibody
  • CFL antibody

Protein level used designations for anti-Cofilin1/2 (CFL1/2) Antibodies

18 kDa phosphoprotein , cofilin, non-muscle isoform , cofilin-1 , p18

1072 Homo sapiens
Selected quality suppliers for anti-Cofilin1/2 (CFL1/2) Antibodies
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