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The function of CCDC170 and its encoded protein is not known. Additionally we are shipping CCDC170 Antibodies (29) and CCDC170 Kits (24) and many more products for this protein.
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Genetic variation at the WLS (show WLS Proteins) and CCDC170/ESR1 (show ESR1 Proteins) loci were found to be significantly associated with bone mineral density
Expression of ESR1 (show ESR1 Proteins), RMND1 (show RMND1 Proteins) and CCDC170 associated with variants in separate enhancer elements predisposing breast cancer. [meta-analysis]
Data suggest that rs2046210 SNPs located in the region of C6ORF97 (CCDC170)-estrogen receptor alpha (ESR1 (show ESR1 Proteins)) might have substantial roles not only in carcinogenesis but also in progression toward a more aggressive phenotype in breast cancer patients.
Our findings suggest that ESR1 (show ESR1 Proteins) and C6orf97 gene polymorphism is associated with fracture and vertebral fracture risk in Chinese postmenopausal women.
ESR1 (show ESR1 Proteins)-CCDC170 rearrangements are found in an aggressive subset of estrogen receptor (show ESR1 Proteins)-positive breast cancers
Variation in rs3757318 of C6orf97 is associated with breast cancer risk.
The function of this gene and its encoded protein is not known. Several genome-wide association studies have implicated the region around this gene to be involved in breast cancer and bone mineral density, but no link to this specific gene has been found.
coiled-coil domain-containing protein 170