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Coiled-Coil Domain Containing 50 Proteins (CCDC50)

CCDC50 encodes a soluble, cytoplasmic, tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Additionally we are shipping Coiled-Coil Domain Containing 50 Antibodies (83) and Coiled-Coil Domain Containing 50 Kits (20) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CCDC50 152137 Q8IVM0
CCDC50 67501 Q810U5
CCDC50 288022 Q810U0
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Top Coiled-Coil Domain Containing 50 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,808.67
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

CCDC50 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

Mouse (Murine)

Rat (Rattus)

More Proteins for Coiled-Coil Domain Containing 50 (CCDC50) Interaction Partners

Human Coiled-Coil Domain Containing 50 (CCDC50) interaction partners

  1. Ymer acts as a regulator downstream of several receptors and that Ymer functions as a positive or negative regulator in a signaling pathway-dependent manner.

  2. identification of a novel DFNA locus on chromosome 3q28-29 in a Spanish family with postlingual and progressive hearing loss[DFNA44]

  3. Ymer functions as a novel inhibitor for the down-regulation of the EGF receptor (show EGFR Proteins) and plays a crucial role for regulating the amount of the EGF receptor (show EGFR Proteins) on the cell surface membrane

  4. These findings demonstrate that Ymer is likely to be a negative regulator for the NF-kappaB (show NFKB1 Proteins) signaling pathway.

  5. CCDC50 is required for survival in mantle cell lymphoma and chronic lymphocytic leukemia cells and controls NFkappaB signaling

Coiled-Coil Domain Containing 50 (CCDC50) Protein Profile

Protein Summary

This gene encodes a soluble, cytoplasmic, tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural DFNA44 hearing loss. In mouse, the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule-based structures. This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF)-mediated cell signaling. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with CCDC50

  • coiled-coil domain containing 50 (CCDC50)
  • coiled-coil domain containing 50 (ccdc50)
  • coiled-coil domain containing 50 (LOC100219219)
  • coiled-coil domain containing 50 (Ccdc50)
  • 2610529H08Rik protein
  • 5730448P06Rik protein
  • AW048328 protein
  • AW546090 protein
  • c3orf6 protein
  • C3orf6h protein
  • D16Bwg1543e protein
  • DFNA44 protein
  • YMER protein

Protein level used designations for CCDC50

coiled-coil domain containing 50 , Ymer protein , coiled-coil domain-containing protein 50 , protein Ymer , putative C3orf6 protein homolog

GENE ID SPECIES
460936 Pan troglodytes
705459 Macaca mulatta
100049085 Xenopus laevis
100219219 Taeniopygia guttata
100380052 Xenopus (Silurana) tropicalis
152137 Homo sapiens
424906 Gallus gallus
478675 Canis lupus familiaris
529404 Bos taurus
67501 Mus musculus
288022 Rattus norvegicus
100715264 Cavia porcellus
101104368 Ovis aries
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