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anti-Coiled-Coil Domain Containing 88A (CCDC88A) Antibodies

CCDC88A encodes a member of the Girdin family of coiled-coil domain containing proteins. Additionally we are shipping Coiled-Coil Domain Containing 88A Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CCDC88A 108686 Q5SNZ0
CCDC88A 305605  
CCDC88A 55704 Q3V6T2
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Top anti-Coiled-Coil Domain Containing 88A Antibodies at antibodies-online.com

Showing 10 out of 63 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using Girdin (Phospho-Ser1417) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Girdin (Ab-1417) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of Girdin in rat brain tissue lysate with AP30364PU-N Girdin antibody at (A) 1 and (B) 2 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human cervical carcinoma labeled with Anti APE/Girdin Polyclonal Antibody, Unconjugated (ABIN755587) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC (p), ELISA 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) Western blot analysis of Girdin in rat brain tissue lysate with Girdin antibody at (A) 1 and (B) 2 µg/ml. 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC, ELISA 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Rabbit Un-conjugated IHC   0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$379.50
Details

CCDC88A Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Coiled-Coil Domain Containing 88A Antibodies

  1. Human Polyclonal CCDC88A Primary Antibody for EIA, WB - ABIN499889 : Anai, Shojima, Katagiri, Ogihara, Sakoda, Onishi, Ono, Fujishiro, Fukushima, Horike, Viana, Kikuchi, Noguchi, Takahashi, Takata, Oka, Uchijima, Kurihara, Asano: A novel protein kinase B (PKB)/AKT-binding protein enhances PKB kinase activity and regulates DNA synthesis. in The Journal of biological chemistry 2005 (PubMed)
    Show all 5 references for ABIN499889

  2. Human Polyclonal CCDC88A Primary Antibody for IHC, ELISA - ABIN1533173 : Simpson, Martin, Evans, Kerr, James, Parton, Teasdale, Wicking: A novel hook-related protein family and the characterization of hook-related protein 1. in Traffic (Copenhagen, Denmark) 2005 (PubMed)
    Show all 2 references for ABIN1533173

  3. Human Polyclonal CCDC88A Primary Antibody for IHC, ELISA - ABIN1532146 : Hillier, Graves, Fulton, Fulton, Pepin, Minx, Wagner-McPherson, Layman, Wylie, Sekhon, Becker, Fewell, Delehaunty, Miner, Nash, Kremitzki, Oddy, Du, Sun, Bradshaw-Cordum, Ali, Carter, Cordes, Harris et al.: Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ... in Nature 2005 (PubMed)
    Show all 2 references for ABIN1532146

  4. Human Polyclonal CCDC88A Primary Antibody for IF (p), IHC (p) - ABIN755587 : Ni, Fang, Tong, Tong, Yi, Qiu, Wang, Tong: Girdin regulates the migration and invasion of glioma cells via the PI3K‑Akt signaling pathway. in Molecular medicine reports 2015 (PubMed)

More Antibodies against Coiled-Coil Domain Containing 88A Interaction Partners

Mouse (Murine) Coiled-Coil Domain Containing 88A (CCDC88A) interaction partners

  1. Akt (show AKT1 Antibodies)-dependent Girdin phosphorylation regulates repair processes after acute myocardial infarction.

  2. GIV expression is up-regulated in liver after fibrotic injury and is required for hepatic stellate cells activation.Girdin is a central hub for profibrogenic signalling networks during liver fibrosis.

  3. GIV and its substrate Galphai3 (show GNAI3 Antibodies) are recruited to active integrin complexes

  4. findings suggest a potential role of Girdin/kinesin-1 interaction in the regulation of neuroblast migration in the postnatal brain

  5. Girdin phosphorylation at Y1798 was found at focal adhesions in NIH3T3 cells. Such phosphorylation was found where migration defects occurred in Girdin KO mice.

  6. Girdin phosphorylation at S1416 induced by Akt (show AKT1 Antibodies) is crucial for NMDA receptor activation associated with LTP (show SCP2 Antibodies).

  7. Girdin was identified as a new and major regulator of the insulin (show INS Antibodies) signal in myoblasts and skeletal muscle.

  8. These results demonstrate that girdin and its phosphorylation play an important role in neonatal vascular development and in pathological neovascularization in the retina.

  9. these findings indicate that loss of Girdin in the nestin (show NES Antibodies) cell lineage underlies the phenotype of Girdin ncKO mice.

  10. Girdin regulates cell movement in biological contexts that require directional cell movement

Human Coiled-Coil Domain Containing 88A (CCDC88A) interaction partners

  1. Phosphorylation of GIV at Tyr (show TYR Antibodies)-1764/Tyr (show TYR Antibodies)-1798 is also required to enhance PI3K (show PIK3CA Antibodies)-Akt (show AKT1 Antibodies) signaling and tumor cell migration in response to integrin stimulation, indicating that GIV functions in Tyr (show TYR Antibodies)(P)-dependent integrin signaling.

  2. CCDC88A is essential for multiple aspects of normal development and loss of CCDC88A is a cause of the PEHO syndrome phenotype.

  3. GIV is an essential upstream component that couples InsR (show INSR Antibodies) to G-protein signaling to enhance the metabolic insulin (show INS Antibodies) response, and impairment of such coupling triggers IR.

  4. Girdin regulates the migration and invasion of glioma cells via the PI3K (show PIK3CA Antibodies)-Akt (show AKT1 Antibodies) signaling pathway.

  5. The expression of Girdin protein in invasive breast cancer is strongly associated with lymph node metastasis.

  6. GIV expression is up-regulated in liver after fibrotic injury and is required for hepatic stellate cells activation.Girdin is a central hub for profibrogenic signalling networks during liver fibrosis.

  7. TAT (show TAT Antibodies)-GIV peptides provide a novel and versatile tool to manipulate Galphai activation downstream of growth factors in a diverse array of pathophysiologic conditions.

  8. transcriptional upregulation of Girdin expression and Girdin-Galphai3 (show GNAI3 Antibodies) signaling play crucial roles in regulating epithelial apicobasal polarity through the PAR (show JTB Antibodies) complex.

  9. GIV directly and constitutively binds the exocyst complex subunit Exo-70 (show EXOC7 Antibodies) and also associates with GLUT4 (show SLC2A4 Antibodies)-storage vesicles (GSVs) exclusively upon insulin (show INS Antibodies) stimulation.

  10. Expression of tumor necrosis factor (show TNF Antibodies) receptor-assicated factor 4 correlates with expression of Girdin and promotes nuclear translocation of Girdin in breast cancer

Coiled-Coil Domain Containing 88A (CCDC88A) Antigen Profile

Protein Summary

This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with CCDC88A

  • coiled-coil domain containing 88A (CCDC88A) antibody
  • zgc:175202 (zgc:175202) antibody
  • coiled coil domain containing 88A (Ccdc88a) antibody
  • A430106J12Rik antibody
  • AI848406 antibody
  • APE antibody
  • C130096N06Rik antibody
  • C330012F17Rik antibody
  • ccdc88a antibody
  • D130005J21Rik antibody
  • DKFZp459N1815 antibody
  • GIRDIN antibody
  • GIV antibody
  • GRDN antibody
  • HkRP1 antibody
  • KIAA1212 antibody
  • MGC175202 antibody
  • RGD1306694 antibody

Protein level used designations for CCDC88A

coiled-coil domain containing 88A , girdin , hook-related protein 1 , golgi-associated microtubule-binding protein HOOK3-like , Akt-phosphorylation enhancer , Hook-related protein 1 , coiled-coil domain-containing protein 88A , g alpha-interacting vesicle-associated protein , girders of actin filament , Galpha-interacting vesicle-associated protein , AKT-phosphorylation enhancer , girders of actin filaments

GENE ID SPECIES
421210 Gallus gallus
533248 Bos taurus
100190968 Pongo abelii
100330741 Danio rerio
108686 Mus musculus
305605 Rattus norvegicus
55704 Homo sapiens
481375 Canis lupus familiaris
Selected quality suppliers for anti-Coiled-Coil Domain Containing 88A (CCDC88A) Antibodies
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