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Coiled-Coil Domain Containing 88A (CCDC88A) ELISA Kits

CCDC88A encodes a member of the Girdin family of coiled-coil domain containing proteins. Additionally we are shipping Coiled-Coil Domain Containing 88A Antibodies (68) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CCDC88A 108686 Q5SNZ0
Anti-Rat CCDC88A CCDC88A 305605  
CCDC88A 55704 Q3V6T2
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Top Coiled-Coil Domain Containing 88A ELISA Kits at antibodies-online.com

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Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human
96 Tests Log in to see 11 to 13 Days
$875.60
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Mouse
96 Tests Log in to see 11 to 13 Days
$875.60
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More ELISA Kits for Coiled-Coil Domain Containing 88A Interaction Partners

Mouse (Murine) Coiled-Coil Domain Containing 88A (CCDC88A) interaction partners

  1. Akt (show AKT1 ELISA Kits)-dependent Girdin phosphorylation regulates repair processes after acute myocardial infarction.

  2. GIV expression is up-regulated in liver after fibrotic injury and is required for hepatic stellate cells activation.Girdin is a central hub for profibrogenic signalling networks during liver fibrosis.

  3. GIV and its substrate Galphai3 (show GNAI3 ELISA Kits) are recruited to active integrin complexes

  4. findings suggest a potential role of Girdin/kinesin-1 interaction in the regulation of neuroblast migration in the postnatal brain

  5. Girdin phosphorylation at Y1798 was found at focal adhesions in NIH3T3 cells. Such phosphorylation was found where migration defects occurred in Girdin KO mice.

  6. Girdin phosphorylation at S1416 induced by Akt (show AKT1 ELISA Kits) is crucial for NMDA receptor activation associated with LTP (show SCP2 ELISA Kits).

  7. Girdin was identified as a new and major regulator of the insulin (show INS ELISA Kits) signal in myoblasts and skeletal muscle.

  8. These results demonstrate that girdin and its phosphorylation play an important role in neonatal vascular development and in pathological neovascularization in the retina.

  9. these findings indicate that loss of Girdin in the nestin (show NES ELISA Kits) cell lineage underlies the phenotype of Girdin ncKO mice.

  10. Girdin regulates cell movement in biological contexts that require directional cell movement

Human Coiled-Coil Domain Containing 88A (CCDC88A) interaction partners

  1. Phosphorylation of GIV at Tyr (show TYR ELISA Kits)-1764/Tyr (show TYR ELISA Kits)-1798 is also required to enhance PI3K (show PIK3CA ELISA Kits)-Akt (show AKT1 ELISA Kits) signaling and tumor cell migration in response to integrin stimulation, indicating that GIV functions in Tyr (show TYR ELISA Kits)(P)-dependent integrin signaling.

  2. CCDC88A is essential for multiple aspects of normal development and loss of CCDC88A is a cause of the PEHO syndrome phenotype.

  3. GIV is an essential upstream component that couples InsR (show INSR ELISA Kits) to G-protein signaling to enhance the metabolic insulin (show INS ELISA Kits) response, and impairment of such coupling triggers IR.

  4. Girdin regulates the migration and invasion of glioma cells via the PI3K (show PIK3CA ELISA Kits)-Akt (show AKT1 ELISA Kits) signaling pathway.

  5. The expression of Girdin protein in invasive breast cancer is strongly associated with lymph node metastasis.

  6. GIV expression is up-regulated in liver after fibrotic injury and is required for hepatic stellate cells activation.Girdin is a central hub for profibrogenic signalling networks during liver fibrosis.

  7. TAT (show TAT ELISA Kits)-GIV peptides provide a novel and versatile tool to manipulate Galphai activation downstream of growth factors in a diverse array of pathophysiologic conditions.

  8. transcriptional upregulation of Girdin expression and Girdin-Galphai3 (show GNAI3 ELISA Kits) signaling play crucial roles in regulating epithelial apicobasal polarity through the PAR (show JTB ELISA Kits) complex.

  9. GIV directly and constitutively binds the exocyst complex subunit Exo-70 (show EXOC7 ELISA Kits) and also associates with GLUT4 (show SLC2A4 ELISA Kits)-storage vesicles (GSVs) exclusively upon insulin (show INS ELISA Kits) stimulation.

  10. Expression of tumor necrosis factor (show TNF ELISA Kits) receptor-assicated factor 4 correlates with expression of Girdin and promotes nuclear translocation of Girdin in breast cancer

Coiled-Coil Domain Containing 88A (CCDC88A) Antigen Profile

Antigen Summary

This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with CCDC88A

  • coiled-coil domain containing 88A (CCDC88A) antibody
  • zgc:175202 (zgc:175202) antibody
  • coiled coil domain containing 88A (Ccdc88a) antibody
  • A430106J12Rik antibody
  • AI848406 antibody
  • APE antibody
  • C130096N06Rik antibody
  • C330012F17Rik antibody
  • ccdc88a antibody
  • D130005J21Rik antibody
  • DKFZp459N1815 antibody
  • GIRDIN antibody
  • GIV antibody
  • GRDN antibody
  • HkRP1 antibody
  • KIAA1212 antibody
  • MGC175202 antibody
  • RGD1306694 antibody

Protein level used designations for CCDC88A

coiled-coil domain containing 88A , girdin , hook-related protein 1 , golgi-associated microtubule-binding protein HOOK3-like , Akt-phosphorylation enhancer , Hook-related protein 1 , coiled-coil domain-containing protein 88A , g alpha-interacting vesicle-associated protein , girders of actin filament , Galpha-interacting vesicle-associated protein , AKT-phosphorylation enhancer , girders of actin filaments

GENE ID SPECIES
421210 Gallus gallus
533248 Bos taurus
100190968 Pongo abelii
100330741 Danio rerio
108686 Mus musculus
305605 Rattus norvegicus
55704 Homo sapiens
481375 Canis lupus familiaris
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