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anti-Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 4 (CHCHD4) Antibodies

CHCHD4, a component of human mitochondria, belongs to a protein family whose members share 6 highly conserved cysteine residues constituting a -CXC-CX(9)C-CX(9)C- motif in the C terminus (Hofmann et al., 2005 [PubMed 16185709]).[supplied by OMIM, Mar 2008].. Additionally we are shipping CHCHD4 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CHCHD4 100361898 Q5BJN5
CHCHD4 131474 Q8N4Q1
CHCHD4 72170 Q8VEA4
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Top anti-CHCHD4 Antibodies at antibodies-online.com

Showing 10 out of 44 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-CHCHD4 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Transfected 293T 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry analysis in human liver tissue (formalin-fixed, paraffin-embedded) using CHCHD4 / MIA40 Antibody (C-term), followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of MIA40 antibody for immunohistochemistry. Clinical relevance has not been evaluated. Western blot analysis in MDA-MB231 cell line lysates (35ug/lane) using CHCHD4 / MIA40 Antibody . This demonstrates the MIA40 antibody detected the MIA40 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB MIA40 Antibody (C-term)  western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the MIA40 antibody detected the MIA40 protein (arrow). MIA40 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MIA40 Antibody (C-term) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB CHCHD4 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit FITC IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated IHC, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Mouse Un-conjugated ELISA, WB CHCHD4 monoclonal antibody (M01), clone 6C9. Western Blot analysis of CHCHD4 expression in HeLa. Detection limit for recombinant GST tagged CHCHD4 is 0.03 ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μg Log in to see 8 to 10 Days
$478.50
Details

CHCHD4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus)


Human ,
,
,
, , , , ,
Mouse (Murine)


Top referenced anti-CHCHD4 Antibodies

  1. Human Polyclonal CHCHD4 Primary Antibody for EIA, IHC (p) - ABIN951496 : Daithankar, Farrell, Thorpe: Augmenter of liver regeneration: substrate specificity of a flavin-dependent oxidoreductase from the mitochondrial intermembrane space. in Biochemistry 2009 (PubMed)
    Show all 3 references for ABIN951496

  2. Chicken Polyclonal CHCHD4 Primary Antibody for WB - ABIN2784679 : Terziyska, Grumbt, Bien, Neupert, Herrmann, Hell: The sulfhydryl oxidase Erv1 is a substrate of the Mia40-dependent protein translocation pathway. in FEBS letters 2007 (PubMed)

More Antibodies against CHCHD4 Interaction Partners

Human Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 4 (CHCHD4) interaction partners

  1. Compared to wild type control littermates, mice with a knockout of CHCHD4 exhibit reduced weight gain when fed a high-fat diet.

  2. Data show that the redox state of cytochrome c oxidase assembly protein 17 (Cox17 (show COX17 Antibodies)), mitochondrial membrane transport protein Mia40 and superoxide dismutase 1 (SOD1 (show SOD1 Antibodies)) in the cytoplasm were directly observed with in-cell NMR spectroscopy.

  3. our findings suggest that MIA40 reduction contributes to the effects of AIF (show AIFM1 Antibodies) deficiency on OXPHOS, as it may impact on the correct assembly and maintenance of the respiratory subunits.

  4. Data indicate that poptosis-inducing factor (AIF (show AIFM1 Antibodies)) controls the mitochondrial import of mitochondrial membrane transport protein CHCHD4.

  5. In aggregate these data suggest that the Mia40/lfALR system has a broad sequence specificity and that potential substrates may be protected from adventitious oxidation by kinetic sequestration within the mitochondrial IMS.

  6. Import and oxidative folding of proteins are kinetically and functionally coupled and depend on the expression of Mia40, ALR (show GFER Antibodies), and the intracellular glutathione pool.

  7. Data indicate that decreased CHCHD4 expression prevents the mitochondrial translocation of p53 (show TP53 Antibodies) while augmenting its nuclear localization and activity.

  8. illustrate a very atypical behaviour for the Mia40 precursor compared to other substrates of the MIA (show MIA Antibodies) pathway. By contrast, interaction with Erv1 (show GFER Antibodies) occurs after 5 min of import and relies on a more stringent specificity

  9. mitochondrial localization of MIA40 requires sulfhydryl oxidase ALR (show GFER Antibodies) in heterologous expression yeast system.

  10. Molecular recognition and substrate mimicry drive the electron-transfer process between MIA40 and ALR (show GFER Antibodies).

CHCHD4 Antigen Profile

Protein Summary

CHCHD4, a component of human mitochondria, belongs to a protein family whose members share 6 highly conserved cysteine residues constituting a -CXC-CX(9)C-CX(9)C- motif in the C terminus (Hofmann et al., 2005

Gene names and symbols associated with CHCHD4

  • coiled-coil-helix-coiled-coil-helix domain containing 4 (chchd4-a) antibody
  • coiled-coil-helix-coiled-coil-helix domain containing 4 (CHCHD4) antibody
  • LY6/PLAUR domain containing 6B (lypd6b) antibody
  • coiled-coil-helix-coiled-coil-helix domain containing 4 (chchd4) antibody
  • coiled-coil-helix-coiled-coil-helix domain containing 4 (chchd4-b) antibody
  • coiled-coil-helix-coiled-coil-helix domain containing 4 (LOC100224104) antibody
  • coiled-coil-helix-coiled-coil-helix domain containing 4 (LOC100361898) antibody
  • coiled-coil-helix-coiled-coil-helix domain containing 4 (Chchd4) antibody
  • similar to internal region of S. cerevisiae essential mitochondrial protein FMP15 (YKL195W); same as cosmid orf Ca49C10.16 (CaO19.10494) antibody
  • 2410012P20Rik antibody
  • 2810014D17Rik antibody
  • AI838740 antibody
  • chchd4 antibody
  • chchd4a antibody
  • chchd4b antibody
  • fc10g04 antibody
  • MIA40 antibody
  • si:dkey-202e22.1 antibody
  • TIMM40 antibody
  • wu:fc10g04 antibody
  • zgc:100849 antibody
  • zgc:113301 antibody

Protein level used designations for CHCHD4

mitochondrial intermembrane space import and assembly protein 40-A , mitochondrial intermembrane space import and assembly protein 40 , coiled-coil-helix-coiled-coil-helix domain-containing protein 4-A , CHCHD4 , coiled-coil-helix-coiled-coil-helix domain-containing protein 4 , coiled-coil-helix-coiled-coil-helix domain containing 4 , mitochondrial intermembrane space import and assembly protein 40-B , coiled-coil-helix-coiled-coil-helix domain-containing protein 4-B , mitochondrial intermembrane space import and assembly 40 homolog , translocase of inner mitochondrial membrane 40 homolog , potential mitochondrial protein

GENE ID SPECIES
414630 Xenopus laevis
416037 Gallus gallus
553752 Danio rerio
476520 Canis lupus familiaris
394473 Xenopus (Silurana) tropicalis
445144 Danio rerio
470755 Pan troglodytes
494790 Xenopus laevis
700814 Macaca mulatta
100224104 Taeniopygia guttata
100361898 Rattus norvegicus
131474 Homo sapiens
72170 Mus musculus
312559 Rattus norvegicus
513889 Bos taurus
3637171 Candida albicans SC5314
Selected quality suppliers for anti-CHCHD4 (CHCHD4) Antibodies
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