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anti-Collagen, Type I, alpha 2 (COL1A2) Antibodies

COL1A2 encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Additionally we are shipping Collagen, Type I, alpha 2 Kits (60) and Collagen, Type I, alpha 2 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
COL1A2 1278 P08123
COL1A2 12843 Q01149
COL1A2 84352 P02466
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Top anti-Collagen, Type I, alpha 2 Antibodies at antibodies-online.com

Showing 10 out of 75 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-COL1A2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Human Liver 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from Jurkat cells, treated with etoposide 25uM 24h, using Collagen I alpha2 (Cleaved-Gly1102) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB COL1A2 Antibody (N-term) (ABIN655509) western blot analysis in T47D cell line lysates (35 µg/lane). This demonstrates the COL1A2 antibody detected the COL1A2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ICC, IF, WB ICC/IF Image COL1A2 antibody [C2C3], C-term detects COL1A2 protein at cytoplasm by immunofluorescent analysis. Sample: NIH-3T3 cells were fixed in ice-cold MeOH for 5 min. Green: COL1A2 protein stained by COL1A2 antibody [C2C3], C-term , diluted at 1:500. Blue: Hoechst 33342 staining. WB Image COL1A2 antibody [C2C3], C-term detects COL1A2 protein by western blot analysis. A. 30 μg 293T whole cell extract B. 30 μg whole cell extract of GFP-human COL1A2-transfected 293T cells (partial) 10 % SDS-PAGE COL1A2 antibody [C2C3], C-term , dilution: 1:5000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB Western blot analysis of extracts from 293/HeLa cells, using Collagen I alpha2 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using Collagen I alpha2 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Dog Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IF, IHC (p), ELISA, WB 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IF, IHC, ELISA 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details

COL1A2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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More Antibodies against Collagen, Type I, alpha 2 Interaction Partners

Human Collagen, Type I, alpha 2 (COL1A2) interaction partners

  1. COL1A2 mutation is associated with atypical osteogenesis imperfect.

  2. analysis of COL1A2 (type I collagen) polymorphisms in the central-eastern Mediterranean Basin

  3. Two gross deletions have been found in the genes coding for collagen type I in the Chinese osteogenesis imperfecta population, and the deletion of exons 17 to 23 in the COL1A2 gene is a novel mutation.

  4. Using TCGA analysis, COL1A1 (show COL1A1 Antibodies) and COL1A2 were found to be up-regulated, which could provide a molecular explanation for the development of blastic metastases.

  5. Collagen I mutation analysis(COL1A1 (show COL1A1 Antibodies) and COL1A2 ) was performed in the family of 97% of known cases, with causative mutations found in 87%. Qualitative mutations caused 32% of Osteogenesis imperfecta type I.

  6. Severe osteogenesis imperfecta caused by double glycine substitutions near the amino-terminal triple helical region in COL1A2.

  7. Data indicate that LA motif protein LARP6 binding to spliced leader RNA (5'SL) of collagen alpha2(I) mRNA is more stable than the binding to 5'SL of alpha1(I) mRNA.

  8. These data indicate a novel functional role of AnxA2 (show ANXA2 Antibodies) in the negative post-transcriptional regulation of type I collagen synthesis in human fibroblasts.

  9. The novel c.946G>T/p.G316C mutation in COL1A2 gene is associated with with osteogenesis imperfecta type I.

  10. This study revealed that Notch (show NOTCH1 Antibodies) signaling-related molecules (including Notch1 (show NOTCH1 Antibodies), Hes1, and others) are expressed in L929 and MRC-5 cells and that Notch (show NOTCH1 Antibodies) signaling regulates the expression of col1alpha1 and col1alpha2 in both cell lines.

Cow (Bovine) Collagen, Type I, alpha 2 (COL1A2) interaction partners

  1. In advanced stage granulomas in Mycobacterium bovis-infected cattle, there was an increase in the expression of type I procollagen

  2. Flow induced alpha2beta1 activation in cells on collagen, but not on fibronectin or fibrinogen. Conversely, alpha5beta1 and alphavbeta3 are activated on fibronectin and fibrinogen, but not collagen.

Mouse (Murine) Collagen, Type I, alpha 2 (COL1A2) interaction partners

  1. Resveratrol effectively inhibits collagen I synthesis in IGF-1 (show IGF1 Antibodies)-stimulated colonic fibroblasts, partly by inhibiting IGF-1R (show IGF1R Antibodies) activation, and SIRT1 (show SIRT1 Antibodies) is also responsible for the process.

  2. Sp7/Osterix (show SP7 Antibodies) induces the mouse Col1a2 expression via the proximal promoter in osteoblastic cells in association with osteoblast differentiation.

  3. Down-regulation let-7 by transforming growth factor-beta1-induced Lin28 (show LIN28A Antibodies) upregulates collagen expression in glomerular mesangial cells from diabetic mice.

  4. Data indicate serine-threonine kinase receptor-associated protein (show STRAP Antibodies) (STRAP) as a novel regulator of the coordinated translation of collagen alpha1(I) and alpha2(I) mRNAs.

  5. The data showed that the Smad (show SMAD1 Antibodies) pathway mediated the expression of type I collagen in radiation induced fibrosis.

  6. MRTF-A (show MKL1 Antibodies) is an important regulator of collagen synthesis in lung fibroblasts and exhibits a dependence on both SRF and Sp1 (show SP1 Antibodies) function to enhance collagen expression

  7. study reports that vimentin (show VIM Antibodies) filaments associate with collagen mRNAs in a 5'stem-loop sequence and LARP6 (show LARP6 Antibodies)-dependent manner and stabilize collagen mRNAs

  8. Muscle weakness in +/oim and oim/oim mice (frameshift mutation in the COL1A2 gene)reflects inherent skeletal muscle pathology.

  9. post-transcriptional regulation of Tsc-22 (show TSC22D1 Antibodies) mediated through Ybx1 (show YBX1 Antibodies), a miR (show MLXIP Antibodies)-216a target, plays a key role in TGF-beta (show TGFB1 Antibodies)-induced Col1a2 in MC related to the pathogenesis of diabetic nephropathy

  10. These findings reveal a novel function of Fra-2 (show FOSL2 Antibodies)/AP-1 (show JUN Antibodies) as a positive regulator of bone and matrix formation in mice and humans.

Pig (Porcine) Collagen, Type I, alpha 2 (COL1A2) interaction partners

Collagen, Type I, alpha 2 (COL1A2) Antigen Profile

Protein Summary

This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.

Gene names and symbols associated with COL1A2

  • collagen type I alpha 2 (LOC100860940) antibody
  • collagen, type 1, alpha 2 (col1a2) antibody
  • collagen, type I, alpha 2 (COL1A2) antibody
  • collagen, type I, alpha 2 (Col1a2) antibody
  • collagen, type I, alpha 2 (col1a2) antibody
  • AA960264 antibody
  • AI325291 antibody
  • alpha2(I) antibody
  • Col1a-2 antibody
  • Cola-2 antibody
  • Cola2 antibody
  • hm:zehn2357 antibody
  • OI4 antibody
  • oim antibody
  • wu:fa98d05 antibody
  • wu:fa99g10 antibody
  • wu:fb04c08 antibody
  • wu:fb11d06 antibody
  • zehn2357 antibody

Protein level used designations for COL1A2

procollagen, type I, alpha 2 , alpha 2(I) collagen , alpha-2 type I collagen , alpha-2(1) collagen , collagen alpha 2(I) chain , collagen alpha-2(I) chain , alpha 2(I)-collagen , collagen I, alpha-2 polypeptide , collagen of skin, tendon and bone, alpha-2 chain , type I procollagen , COL1A2 gene exons 8 through 12 , type I procollagen pro-alpha 2 chain , alpha 2(I) procollagen , collagen I alpha-2 polypeptide , collagen COL1A2 , osteogenesis imperfecta , alpha 2 type I collagen , collagen a2(I)

GENE ID SPECIES
100860940 Capra hircus
380419 Xenopus laevis
396243 Gallus gallus
1278 Homo sapiens
403824 Canis lupus familiaris
282188 Bos taurus
100008997 Oryctolagus cuniculus
12843 Mus musculus
84352 Rattus norvegicus
100719158 Cavia porcellus
100626716 Sus scrofa
336471 Danio rerio
100135811 Oncorhynchus mykiss
Selected quality suppliers for anti-Collagen, Type I, alpha 2 (COL1A2) Antibodies
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