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Collagen, Type III, alpha 1 Proteins (COL3A1)

COL3A1 encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Additionally we are shipping COL3A1 Antibodies (96) and COL3A1 Kits (43) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
COL3A1 1281 P02461
COL3A1 12825 P08121
COL3A1 84032 P13941
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Top COL3A1 Proteins at antibodies-online.com

Showing 10 out of 14 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
$774.40
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Escherichia coli (E. coli) Human His tag,HIS-GST   100 μg Log in to see 11 to 13 Days
$844.80
Details
HOST_Escherichia coli (E. coli) Rat His tag   100 μg Log in to see 11 to 13 Days
$844.80
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 3 to 4 Days
$310.00
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 9 to 19 Days
$952.01
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$1,014.95
Details
HOST_Escherichia coli (E. coli) Rat Un-conjugated   100 μg Log in to see 9 to 19 Days
$1,014.95
Details

COL3A1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
, ,
Mouse (Murine)

Rat (Rattus)

More Proteins for Collagen, Type III, alpha 1 (COL3A1) Interaction Partners

Pig (Porcine) Collagen, Type III, alpha 1 (COL3A1) interaction partners

Horse (Equine) Collagen, Type III, alpha 1 (COL3A1) interaction partners

  1. The present results suggest that not only type III collagen but also cartilage oligomeric matrix protein (show COMP Proteins) is involved in the repair and remodeling processes of the digital flexor tendon.

Human Collagen, Type III, alpha 1 (COL3A1) interaction partners

  1. A novel missense mutation in COL3A1 was found in a young patient with cervical artery dissection as the single manifestation of Ehlers-Danlos syndrome.

  2. the clinical phenotype of Ehlers-Danlos syndrome patients is influenced by the type of COL3A1 variant.

  3. Report dysregulated expression of COL3A1 in disc degeneration.

  4. TGFbeta (show TGFB1 Proteins) target genes including TGFBI (show TGFBI Proteins), BAMBI (show BAMBI Proteins), COL3A1 and SERPINE1 (show SERPINE1 Proteins) are significantly increased in Diamond Blackfan Anemia induced pluripotent stem cells

  5. These results suggest that let-7d may suppress renal cell carcinoma (show MOK Proteins) growth, metastasis, and tumor macrophage infiltration at least partially through targeting COL3A1 and CCL7 (show CCL7 Proteins).

  6. compare reported phenotypes for patients with missense variants in the C-propeptide domain for other human collagen disorders including COL1A1 (show COL1A1 Proteins) and COL1A2 (osteogenesis imperfecta (show COL1A2 Proteins)).

  7. miR (show MLXIP Proteins)-29a and miR (show MLXIP Proteins)-29b enhance cell migration and invasion in nasopharyngeal carcinoma progression by regulating SPARC (show SPARC Proteins) and COL3A1 gene expression.

  8. Data indicate that N-terminal propeptide of type III procollagen (PIIINP) is a highly effective means to evaluate left ventricular (LV) end-diastolic pressure (EDP) in patients with acute coronary syndrome (ACS).

  9. The first main finding of this study was that the rare COL3A1 rs1800255 AA genotype was associated with increased risk of anterior cruciate ligament injuries in the Polish cohort but not the South African cohort.

  10. During heart valve development, Krox20 (show EGR2 Proteins)-mediated activation of fibrillar Col1a1 (show COL1A1 Proteins) and Col3a1 genes is crucial to avoid postnatal degeneration of the aortic valve leaflets.

Mouse (Murine) Collagen, Type III, alpha 1 (COL3A1) interaction partners

  1. Tsk2 expressing mice harbor numerous autoantibodies in their plasma, including some which are similar to antinuclear antibodies present in systemic sclerosis patients.

  2. Tight skin (show FBN1 Proteins) 2 mice exhibit a novel time line of events leading to increased extracellular matrix deposition and dermal fibrosis.

  3. Tsk2 point mutation is the first documented gain-of-function mutation associated with Col3a1, which leads instead to fibrosis.

  4. Col3 plays a role in development of trabecular bone through its effects on osteoblast differentiation

  5. Type I collagen turnover is critical to large pulmonary artery remodeling during hypoxic pulmonary hypertension when collagen metabolism is not mutated and type III collagen may serve as a reserve.

  6. Our findings demonstrated the extreme sensitivity of Col3a1 insufficient mice to prematurely develop thoracic aortic ruptures in response to AngII and its associated high levels in BP.

  7. Data show that that Col3a1 null mutant mice exhibit overmigration of neurons beyond the pial basement membrane and a cobblestone-like cortical malformation similar to the phenotype seen in Gpr56 (show GPR56 Proteins) null mutant mice.

  8. Diminished type III collagen promotes myofibroblast differentiation and increases scar deposition in cutaneous wound healing

  9. Spontaneous deletion in the promoter region and exons 1-39 of the murine Col3a1 locus has produced a relevant and exploitable model of the vascular dissection in vascular Ehlers-Danlos syndrome.

  10. Data indicate that COL3A1 intronic miRNAs may regulate the expression of other collagen genes in development.

Cow (Bovine) Collagen, Type III, alpha 1 (COL3A1) interaction partners

  1. specific ADAMTS-2 domains cleave the aminopropeptide of fibrillar procollagens types I-III and V

Rabbit Collagen, Type III, alpha 1 (COL3A1) interaction partners

  1. Ammonium perchlorate can increase gene expressions of types I, III collagens, TGF-beta(1 (show TGFB1 Proteins)) and TNF-alpha (show TNF Proteins) in lung of rabbits.

COL3A1 Protein Profile

Protein Summary

This gene encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome types IV, and with aortic and arterial aneurysms. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.

Gene names and symbols associated with COL3A1

  • collagen, type III, alpha 1 (COL3A1)
  • collagen, type III, alpha 1 (col3a1)
  • collagen type III alpha 1 (LOC100860938)
  • collagen, type III, alpha 1 (Col3a1)
  • pro alpha 1 type III collagen (LOC100009177)
  • AW550625 protein
  • Col3a-1 protein
  • COL3A1 protein
  • EDS4A protein
  • mKIAA4231 protein
  • MMS10-W protein
  • Ms10w protein

Protein level used designations for COL3A1

collagen, type III, alpha 1 , type III collagen , collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) , collagen alpha-1(III) chain , collagen alpha-1(III) chain preproprotein , collagen type III alpha 1 , procollagen alpha-1 type III , Ehlers-Danlos syndrome type IV, autosomal dominant , alpha1 (III) collagen , collagen, fetal , minisatellite 10w detected by probe MMS10 , procollagen, type III, alpha 1 , collagen, type III, alpha 1 chain, fibril forming , alpha 1 type III collagen , pro-alpha-1 type 3 collagen , collagen alpha 1 type III

GENE ID SPECIES
396990 Sus scrofa
459815 Pan troglodytes
574131 Macaca mulatta
100034123 Equus caballus
100220437 Taeniopygia guttata
100028423 Monodelphis domestica
100543004 Meleagris gallopavo
100556853 Anolis carolinensis
100587191 Nomascus leucogenys
100860938 Capra hircus
1281 Homo sapiens
12825 Mus musculus
510833 Bos taurus
396340 Gallus gallus
84032 Rattus norvegicus
100727269 Cavia porcellus
100152001 Sus scrofa
478835 Canis lupus familiaris
443237 Ovis aries
100009177 Oryctolagus cuniculus
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