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anti-Collagen, Type IV, alpha 5 (COL4a5) Antibodies

COL4a5 encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Additionally we are shipping COL4a5 Proteins (2) and COL4a5 Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
COL4a5 1287 P29400
COL4a5 12830  
COL4a5 363457  
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Top anti-COL4a5 Antibodies at antibodies-online.com

Showing 10 out of 44 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF, IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using Collagen IV alpha5 Antibody. The picture on the right is treated with the synthesized peptide. Immunofluorescence analysis of HeLa cells, using Collagen IV alpha5 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of Collagen 4 alpha 5 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of Collagen 4 alpha 5 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated IF, IHC (p), ELISA 100 μL Log in to see 7 to 9 Days
$493.17
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cells, using COL4A5 antibody. 100 μL Log in to see 14 Days
$275.00
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$415.58
Details
Human Rabbit Un-conjugated ELISA, IF, IHC   100 μL Log in to see 14 Days
$175.80
Details
Human Mouse Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$270.60
Details
Human Rabbit Un-conjugated ICC, IHC, IP, WB 100 μg Log in to see 11 to 13 Days
$385.00
Details
Human Rabbit Un-conjugated EIA, IHC (fro), WB   0.1 mg Log in to see 6 to 8 Days
$555.50
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, IHC, IHC (p)   0.05 mL Log in to see 8 to 11 Days
$278.25
Details

COL4a5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,
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Mouse (Murine) , , ,


Rat (Rattus)


More Antibodies against COL4a5 Interaction Partners

Human Collagen, Type IV, alpha 5 (COL4a5) interaction partners

  1. Synonymous COL4A5 substitution responsible for X-linked Alport syndrome.

  2. Sanger sequencing of these regions identified a novel splicesite mutation in intron 9 (c.547-3C>A) of the COL4A5 gene. Subsequent cDNA analysis revealed that c.547- 3C>A led to skipping of exon 10, which resulted in an in-frame deletion of 21 amino acids from the a5 chain of type IV collagen (show COL4 Antibodies). This is the first report of the novel c.547-3C>A splicing mutation in the collagen domain of COL4A5 gene.

  3. Coinheritance of COL4A5 and MYO1E (show MYO1E Antibodies) mutations accentuate the severity of kidney disease.

  4. Case Report: subepidermal blistering disease with autoantibodies to multiple laminin subunits which developed autoantibodies to COL4A5 associated with membranous glomerulonephropathy.

  5. New COL4A5 mutations among Portuguese patients with collagen IV (show COL4 Antibodies)-related nephropathies were identified in unrelated individuals.

  6. alpha5(IV), but not alpha1(IV), promotes lung cancer cell proliferation and tumor angiogenesis through non-integrin collagen receptor (show ITGA2 Antibodies) DDR1 (show DDR1 Antibodies)-mediated ERK (show EPHB2 Antibodies) activation.

  7. we identified seven families with associated mutations in COL4A3 (show COL4a3 Antibodies) and COL4A4 (show Col4a4 Antibodies) genes and four families with associated mutations in COL4A4 (show Col4a4 Antibodies) and COL4A5. We did not find kindreds with digenic inheritance attributable to mutations in COL4A3 (show COL4a3 Antibodies) and COL4A5

  8. The expression of collagen type IV (show COL4 Antibodies) and its alpha chains (alpha1-6) was investigated in different endothelial cell culture systems in vitro qualitatively and quantitatively.

  9. New deletion in COL4A6 (show COL4a6 Antibodies)/COL4A5 related to diffuse esophageal leiomyomatosis associated with Alport syndrome in a Chinese family.

  10. We identified a nucleotide change 1226 G>A, causing amino acid substitutions of Gly to Asp (show ASIP Antibodies) at position 409, in hemizygosis in the exon 20 of COL4A5 gene (proband 16 and the 13 in Alport syndrome pedigree

Mouse (Murine) Collagen, Type IV, alpha 5 (COL4a5) interaction partners

  1. Findings indicate a role for collagen alpha-5(IV) chain (Col4a5) in the regulation of macrophage responses to mycobacterial infection and identify Col4a5 as a potential target for the host-directed anti-mycobacterial therapy.

  2. alpha5(IV), but not alpha1(IV), promotes lung cancer cell proliferation and tumor angiogenesis through non-integrin collagen receptor (show ITGA2 Antibodies) DDR1 (show DDR1 Antibodies)-mediated ERK (show EPHB2 Antibodies) activation.

  3. In murine embryos, collagen IV (show COL4 Antibodies) subunits alpha1(IV), alpha2(IV), alpha5(IV) and alpha6(IV) were detected in the basement membrane surrounding the lens vesicle, and they persisted in the capsule until adulthood.

  4. In kidney, when expressed onto Col4a3 (show COL4a3 Antibodies)(-/-) background, human alpha3(IV (show COL4a3 Antibodies)) chain restored expression of and co-assembled with mouse alpha4 and alpha5(IV) chains at sites where human alpha3(IV (show COL4a3 Antibodies)) was expressed. All three chains required for network assembly.

  5. Alpha3(IV (show COL4a3 Antibodies)), alpha4(IV), and alpha5(IV) chains form a complex, which is a heterotrimer, and a defect in complex formation might be one of the molecular mechanisms underlying the pathogenesis of Alport syndrome.

  6. the proximal bifunctional promoter regulates the expression of the alpha5(IV) and alpha6(IV) genes in a cell-specific manner and demonstrates promoter plasticity in growth factor regulation of type IV collagen (show COL4 Antibodies) genes in different tissues of the body.

COL4a5 Antigen Profile

Protein Summary

This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Mutations in this gene are associated with X-linked Alport syndrome, also known as hereditary nephritis. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Alternatively spliced transcript variants have been identified for this gene.

Gene names and symbols associated with COL4a5

  • collagen, type IV, alpha 5 (COL4A5) antibody
  • collagen, type IV, alpha 1 (col4a1) antibody
  • collagen, type IV, alpha 5 (LOC100285389) antibody
  • collagen, type IV, alpha 5 (Col4a5) antibody
  • ASLN antibody
  • ATS antibody
  • CA54 antibody
  • col4a5 antibody
  • fj65e07 antibody
  • im:7157877 antibody
  • RGD1565499 antibody
  • si:ch211-174g17.1 antibody
  • wu:fj65e07 antibody

Protein level used designations for COL4a5

collagen, type IV, alpha 5 , type IV collagen alpha 5-like , type IV collagen alpha 5 chain , collagen alpha-5(IV) chain-like , collagen IV, alpha-5 polypeptide , collagen alpha-5(IV) chain , collagen of basement membrane, alpha-5 chain , dA149D17.3 , dA24A23.1 , collagen type IV alpha5 chain , procollagen type IV alpha 5 , procollagen, type IV, alpha 5 , collagen, type IV, alpha 5 (Alport syndrome) , type IV collagen alpha 5

GENE ID SPECIES
511602 Bos taurus
554269 Danio rerio
703814 Macaca mulatta
100519180 Sus scrofa
465805 Pan troglodytes
100285389 Zea mays
1287 Homo sapiens
12830 Mus musculus
363457 Rattus norvegicus
403466 Canis lupus familiaris
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