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COL4a6 encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Additionally we are shipping COL4a6 Proteins (2) and COL4a6 Kits (1) and many more products for this protein.
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Human Polyclonal COL4a6 Primary Antibody for ELISA - ABIN4264320
Zhang, Zhou, Reeders, Tryggvason: Structure of the human type IV collagen COL4A6 gene, which is mutated in Alport syndrome-associated leiomyomatosis. in Genomics 1996
Show all 2 Pubmed References
the shiomaneki (sio) gene locus encodes Col4a6, a subunit of type IV collagen (show COL4 Antibodies), which, in a complex with Col4a5 (show COL4A1 Antibodies), is a basement membrane (BM) component. Both col4a5 (show COL4A1 Antibodies) and col4a6 mutants displayed similar abnormalities in the axogenesis
the collagen IV (show COL4 Antibodies) sheet anchors secreted factors at the surface of the tectum, which serve as guidance cues for retinal axons.
Mutation in COL4A6 gene is associated with gastric cancer peritoneal carcinomatosis.
The expression of collagen type IV (show COL4 Antibodies) and its alpha chains (alpha1-6) was investigated in different endothelial cell culture systems in vitro qualitatively and quantitatively.
New deletion in COL4A6/COL4A5 (show COL4a5 Antibodies) related to diffuse esophageal leiomyomatosis associated with Alport syndrome in a Chinese family.
COL4A6 is associated with X-linked nonsyndromic hearing loss.
We showed that TPM2 (show TPM2 Antibodies), CLU (show CLU Antibodies), and COL4A6 mRNA levels are downregulated in prostate cancer.
In this paper we improve the definition of the COL4A5 (show COL4a5 Antibodies)/COL4A6 deletions in three Alport syndrome with diffuse leiomyomatosis.
The expression of Col (show HDAC1 Antibodies) I, Col (show HDAC1 Antibodies) IV and Fn was closely related to tumor invasion, the regional lymph node metastasis and other pathological features in laryngeal squamous cell carcinoma.
expression of collagen type IV (show COL4 Antibodies) alpha6 chain in the smooth muscle BM of the gastrointestinal tract is restricted to the esophagus in humans
The expression of collagen type IV (show COL4 Antibodies) was significantly decreased in colorectal cancer tissues.
We provide a first indication that highly specialized patterns characteristic of COL4A5 (show COL4a5 Antibodies)-COL4A6 expression in vivo arise from effects of distributed cis (show CISH Antibodies)-acting regulatory elements on a bidirectional proximal promoter, itself transcriptionally competent.
In murine embryos, collagen IV (show COL4 Antibodies) subunits alpha1(IV), alpha2(IV), alpha5(IV) and alpha6(IV) were detected in the basement membrane surrounding the lens vesicle, and they persisted in the capsule until adulthood.
the proximal bifunctional promoter regulates the expression of the alpha5(IV) and alpha6(IV) genes in a cell-specific manner and demonstrates promoter plasticity in growth factor regulation of type IV collagen (show COL4 Antibodies) genes in different tissues of the body.
This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene, alpha 5 type IV collagen, so that the gene pair shares a common promoter. Deletions in the alpha 5 gene that extend into the alpha 6 gene result in diffuse leiomyomatosis accompanying the X-linked Alport syndrome caused by the deletion in the alpha 5 gene. Two splice variants have been identified for this gene.
collagen type IV alpha 6 chain
, collagen, type IV, alpha 6
, type IV alpha 6 collagen
, type IV collagen alpha 6 chain
, collagen alpha-6(IV) chain-like
, collagen IV, alpha-6 polypeptide
, collagen alpha-6(IV) chain
, collagen of basement membrane, alpha-6
, dJ889N15.4 (Collagen Alpha 6(IV))
, procollagen type IV alpha 6
, procollagen, type IV, alpha 6