Collagen, Type IV, alpha 6 Proteins (COL4a6)

COL4a6 encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Additionally we are shipping COL4a6 Antibodies (55) and COL4a6 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
COL4a6 1288 Q14031
Mouse COL4a6 COL4a6 94216  
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Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days

COL4a6 Proteins by Origin and Source

Origin Expressed in Conjugate

More Proteins for Collagen, Type IV, alpha 6 (COL4a6) Interaction Partners

Zebrafish Collagen, Type IV, alpha 6 (COL4a6) interaction partners

  1. the shiomaneki (sio) gene locus encodes Col4a6, a subunit of type IV collagen (show COL4 Proteins), which, in a complex with Col4a5 (show COL4A1 Proteins), is a basement membrane (BM) component. Both col4a5 (show COL4A1 Proteins) and col4a6 mutants displayed similar abnormalities in the axogenesis

  2. the collagen IV (show COL4 Proteins) sheet anchors secreted factors at the surface of the tectum, which serve as guidance cues for retinal axons.

Human Collagen, Type IV, alpha 6 (COL4a6) interaction partners

  1. Mutation in COL4A6 gene is associated with gastric cancer peritoneal carcinomatosis.

  2. The expression of collagen type IV (show COL4 Proteins) and its alpha chains (alpha1-6) was investigated in different endothelial cell culture systems in vitro qualitatively and quantitatively.

  3. New deletion in COL4A6/COL4A5 (show COL4a5 Proteins) related to diffuse esophageal leiomyomatosis associated with Alport syndrome in a Chinese family.

  4. COL4A6 is associated with X-linked nonsyndromic hearing loss.

  5. We showed that TPM2 (show TPM2 Proteins), CLU (show CLU Proteins), and COL4A6 mRNA levels are downregulated in prostate cancer.

  6. In this paper we improve the definition of the COL4A5 (show COL4a5 Proteins)/COL4A6 deletions in three Alport syndrome with diffuse leiomyomatosis.

  7. The expression of Col (show HDAC1 Proteins) I, Col (show HDAC1 Proteins) IV and Fn was closely related to tumor invasion, the regional lymph node metastasis and other pathological features in laryngeal squamous cell carcinoma.

  8. expression of collagen type IV (show COL4 Proteins) alpha6 chain in the smooth muscle BM of the gastrointestinal tract is restricted to the esophagus in humans

  9. The expression of collagen type IV (show COL4 Proteins) was significantly decreased in colorectal cancer tissues.

  10. We provide a first indication that highly specialized patterns characteristic of COL4A5 (show COL4a5 Proteins)-COL4A6 expression in vivo arise from effects of distributed cis (show CISH Proteins)-acting regulatory elements on a bidirectional proximal promoter, itself transcriptionally competent.

Mouse (Murine) Collagen, Type IV, alpha 6 (COL4a6) interaction partners

  1. In murine embryos, collagen IV (show COL4 Proteins) subunits alpha1(IV), alpha2(IV), alpha5(IV) and alpha6(IV) were detected in the basement membrane surrounding the lens vesicle, and they persisted in the capsule until adulthood.

  2. the proximal bifunctional promoter regulates the expression of the alpha5(IV) and alpha6(IV) genes in a cell-specific manner and demonstrates promoter plasticity in growth factor regulation of type IV collagen (show COL4 Proteins) genes in different tissues of the body.

COL4a6 Protein Profile

Protein Summary

This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene, alpha 5 type IV collagen, so that the gene pair shares a common promoter. Deletions in the alpha 5 gene that extend into the alpha 6 gene result in diffuse leiomyomatosis accompanying the X-linked Alport syndrome caused by the deletion in the alpha 5 gene. Two splice variants have been identified for this gene.

Gene names and symbols associated with COL4a6

  • collagen, type IV, alpha 6 (COL4A6)
  • collagen, type IV, alpha 6 (col4a6)
  • collagen, type IV, alpha 6 (Col4a6)
  • BB116301 protein
  • CXDELq22.3 protein
  • DELXq22.3 protein

Protein level used designations for COL4a6

collagen type IV alpha 6 chain , collagen, type IV, alpha 6 , type IV alpha 6 collagen , type IV collagen alpha 6 chain , collagen alpha-6(IV) chain-like , collagen IV, alpha-6 polypeptide , collagen alpha-6(IV) chain , collagen of basement membrane, alpha-6 , dJ889N15.4 (Collagen Alpha 6(IV)) , procollagen type IV alpha 6 , procollagen, type IV, alpha 6

403840 Canis lupus familiaris
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465804 Pan troglodytes
523526 Bos taurus
554268 Danio rerio
703707 Macaca mulatta
100152680 Sus scrofa
100338437 Oryctolagus cuniculus
100479688 Ailuropoda melanoleuca
100493153 Xenopus (Silurana) tropicalis
100554629 Anolis carolinensis
100587255 Nomascus leucogenys
1288 Homo sapiens
94216 Mus musculus
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