You are viewing an incomplete version of our website. Please click to reload the website as full version.

Collagen, Type VI, alpha 1 Proteins (COL6A1)

The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Additionally we are shipping Collagen, Type VI, alpha 1 Antibodies (45) and Collagen, Type VI, alpha 1 Kits (36) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
COL6A1 1291 P12109
COL6A1 12833 Q04857
Rat COL6A1 COL6A1 294337  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Collagen, Type VI, alpha 1 Proteins at antibodies-online.com

Showing 7 out of 12 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$844.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Mouse His tag   100 μg Log in to see 11 to 13 Days
$756.80
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$936.27
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 9 to 19 Days
$936.27
Details

COL6A1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Collagen, Type VI, alpha 1 (COL6A1) Interaction Partners

Zebrafish Collagen, Type VI, alpha 1 (COL6A1) interaction partners

Human Collagen, Type VI, alpha 1 (COL6A1) interaction partners

  1. COL6A1 may have a role in progression and outcome of clear cell renal cell carcinoma (show MOK Proteins)

  2. worsening of the functional disability appeared typically after the age of 40 in 47% of our patients with Bethlem myopathy, and was frequently associated with COL6A1 exon 14 skipping

  3. The second main finding of this study was that COL6A1 rs35796750 did not associate with the risk of anterior cruciate ligament injury in the self-reported Caucasian South African cohort.

  4. Data indicate that collagen-VI-alpha-1 (COL6A1) is expressed in all grades of glioma.

  5. Parental mosaicism was confirmed in the four families through quantitative analysis of the ratio of mutant versus wild-type allele (COL6A1, COL6A2 (show COL6A2 Proteins), and COL6A3 (show COL6a3 Proteins)) in genomic DNA from various tissues; consistent with somatic mosaicism, parental samples had lower ratios of mutant versus wild-type allele compared with the fully heterozygote offspring.

  6. In UCDM, 1 mutation was indentified in COL6A1 in Chinese patients.

  7. These results suggest that these SNPs of BMP-2 (show BMP2 Proteins) and COL6A1 may not directly influence the expression of OPLL.

  8. Absence of ANXA2 (show ANXA2 Proteins) leads to retention of COL6 in a late-Golgi, VAMP2 (show VAMP2 Proteins)-positive compartment.

  9. Mutations in each of the three collagen VI genes, COL6A1, COL6A2 (show COL6A2 Proteins) and COL6A3 (show COL6a3 Proteins), cause four types of muscle disorders: Ullrich congenital muscular dystrophy, Bethlem myopathy, limb-girdle muscular dystrophy, and autosomal recessive myosclerosis. (Review)

  10. XPD (show ERCC2 Proteins) mutations in trichothiodystrophy hamper COL6A1 expression.

Cow (Bovine) Collagen, Type VI, alpha 1 (COL6A1) interaction partners

Mouse (Murine) Collagen, Type VI, alpha 1 (COL6A1) interaction partners

  1. Results show that a lack of collagen VI in Col6a1 -/- mice prevents macrophage recruitment and phenotypic transition after sciatic nerve crush, which in turn inhibits peripheral nervous system regeneration

  2. Col6a1 was not required for TRPV4 (show TRPV4 Proteins)-mediated Ca signaling. Knockout of Col6a1 altered the mechanical properties of the pericellular matrix, which increased the extent of cell swelling and osmotically induced TRPV4 (show TRPV4 Proteins) signaling in an age-dependent manner.

  3. Detected is a decreased tensile strength of the skin and an altered collagen fibril and basement membrane architecture in Col6a1 null mice, the latter being features that are also found in collagen VI myopathy patients.

  4. Lack of collagen VI in Col6a1(-/-) mice causes impaired muscle regeneration and reduced satellite cell self-renewal capability after injury.

  5. The expression of Col6a1 in 10T1/2 was also significantly higher than that in other feeder cells. It promoted the colony formation of epithelial cells in vitro effectively.

  6. Physical training exacerbated the dystrophic phenotype of Col6a1-/- mice, where autophagy flux is compromised.

  7. the accumulation of abnormal mitochondria and sarcoplasmic reticulum is caused by a defect of autophagy and that restoration of a proper autophagic flux in Col6a1-/- muscles ameliorates these alterations.

  8. Membrane elasticity was significantly reduced in Col6a1-/- and increased in mdx (show DMD Proteins) fibers.

  9. the Col6a1 promoter has a growth arrest responsive region responsible for transcriptional regulation

  10. a Col6a1 gene enhancer region that is necessary for activation of transcription in connective tissue cells associated with skeletal muscle.

Collagen, Type VI, alpha 1 (COL6A1) Protein Profile

Protein Summary

The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy.

Gene names and symbols associated with COL6A1

  • collagen, type VI, alpha 1 (COL6A1)
  • collagen, type VI, alpha 1 (col6a1)
  • collagen, type VI, alpha 1 (LOC100226931)
  • collagen, type VI, alpha 1 (Col6a1)
  • collagen, type VI, alpha 1 (LOC100343947)
  • AI747156 protein
  • Col6a-1 protein
  • COL6A1 protein
  • OPLL protein
  • RGD1565398 protein

Protein level used designations for COL6A1

collagen, type VI, alpha 1 , type IV collagen alpha 1 subunit , alpha-1 type VI collagen , collagen alpha-1(VI) chain , alpha 1 (VI) chain (61 AA) , collagen VI, alpha-1 polypeptide , collagen type VI alpha 1 , procollagen, type VI, alpha 1 , collagen VI-alpha1 protein , type VI collagen alpha 3 chain

GENE ID SPECIES
450204 Pan troglodytes
569755 Danio rerio
574264 Macaca mulatta
100226931 Taeniopygia guttata
100602363 Nomascus leucogenys
100617956 Monodelphis domestica
396000 Gallus gallus
1291 Homo sapiens
100101553 Sus scrofa
511422 Bos taurus
12833 Mus musculus
294337 Rattus norvegicus
100343947 Oryctolagus cuniculus
100732346 Cavia porcellus
403668 Canis lupus familiaris
443051 Ovis aries
380129 Xenopus laevis
Selected quality suppliers for Collagen, Type VI, alpha 1 Proteins (COL6A1)
Did you look for something else?