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anti-Collagen, Type VI, alpha 2 (COL6A2) Antibodies

COL6A2 encodes one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. Additionally we are shipping Collagen, Type VI, alpha 2 Kits (5) and Collagen, Type VI, alpha 2 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
COL6A2 1292 P12110
COL6A2 12834 Q02788
COL6A2 361821  
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Top anti-Collagen, Type VI, alpha 2 Antibodies at antibodies-online.com

Showing 10 out of 55 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB COL6A2 Antibody (C-term) western blot analysis in MDA-MB453 cell line lysates (35µg/lane).This demonstrates the COL6A2 antibody detected the COL6A2 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-COL6A2 Antibody Titration: 1.25ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunohistochemistry: Collagen VI alpha 2 Antibody [NBP1-90951] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp.Lane 4: Human plasma (IgG/HSA depleted).Lane 5: Human liver tissue.Lane 6: Human tonsil tissue Immunohistochemistry-Paraffin: Collagen VI alpha 2 Antibody [NBP1-90951] - Staining of human stomach shows strong cytoplasmic positivity in glandular cells. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated ELISA, IF, IHC, WB 100 μL Log in to see 14 Days
$175.80
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from K562/A549/HT-29/COS7 cells, using Collagen VI alpha2 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Collagen VI alpha2 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB COL6A2 Antibody (C-term)  western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the COL6A2 antibody detected the COL6A2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IC, IF, IP, IHC, WB Immunofluorescent analysis of Collagen 6 alpha 2 staining in HT29 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of Collagen 6 alpha 2 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Horse Rabbit Un-conjugated WB 100 μg Log in to see 7 to 9 Days
$493.17
Details
Human Mouse Un-conjugated WB Western Blot analysis of COL6A2 expression in transfected 293T cell line by COL6A2 monoclonal antibody (M01), clone 2C5-F2. Lane 1: COL6A2 transfected lysate(109 KDa). Lane 2: Non-transfected lysate. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extract of various cells, using COL6A2 antibody. 100 μL Log in to see 14 Days
$460.63
Details

COL6A2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human
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Mouse (Murine)


Rat (Rattus)


Top referenced anti-Collagen, Type VI, alpha 2 Antibodies

  1. Human Polyclonal COL6A2 Primary Antibody for IHC, IHC (p) - ABIN4299696 : Liu, Carson-Walter, Cooper, Winans, Johnson, Walter: Vascular gene expression patterns are conserved in primary and metastatic brain tumors. in Journal of neuro-oncology 2010 (PubMed)
    Show all 2 references for ABIN4299696

  2. Human Polyclonal COL6A2 Primary Antibody for EIA, WB - ABIN951625 : Zhang, Zou, Pan, Markova, Fertala, Hu, Squarzoni, Reed, Marie, Bönnemann, Chu: Recessive COL6A2 C-globular missense mutations in Ullrich congenital muscular dystrophy: role of the C2a splice variant. in The Journal of biological chemistry 2010 (PubMed)

More Antibodies against Collagen, Type VI, alpha 2 Interaction Partners

Human Collagen, Type VI, alpha 2 (COL6A2) interaction partners

  1. Genetic study showed a missense mutation in COL6A2 (c.820 G>A, p.Gly268Ser) that causes a glycine substitution in the Gly-X-Y collagenous motif, at the beginning of the collagenous triple helical domain. The c.820 G>A mutation segregated in all the affected patients.

  2. Parental mosaicism was confirmed in the four families through quantitative analysis of the ratio of mutant versus wild-type allele (COL6A1 (show COL6A1 Antibodies), COL6A2, and COL6A3 (show COL6a3 Antibodies)) in genomic DNA from various tissues; consistent with somatic mosaicism, parental samples had lower ratios of mutant versus wild-type allele compared with the fully heterozygote offspring.

  3. Mutations in COL6A2 gene are associated with aberrant mitochondria in Bethlem myopathy.

  4. In UCMD, 8 mutations were identified in COL6A2 in Chinese patients.

  5. Mutations in each of the three collagen VI genes, COL6A1 (show COL6A1 Antibodies), COL6A2 and COL6A3 (show COL6a3 Antibodies), cause four types of muscle disorders: Ullrich congenital muscular dystrophy, Bethlem myopathy, limb-girdle muscular dystrophy, and autosomal recessive myosclerosis. (Review)

  6. COL6A2 is overexpressed in Down syndrome-affected umbilical cords at early and term gestational ages.

  7. Homozygous COL6A2 mutation, p.Asp215Asn, was identified in both affected siblings. We conclude that the COL6A2 p.Asp215Asn mutation is likely to be responsible for PME (show CSTB Antibodies) (Progressive Myoclonus Epilepsy) in this family.

  8. A deletion within intron 1A of the COL6A2 gene, occurring in compound heterozygosity with a small deletion in exon 28, was identified in a BM patient.

  9. the C2A splice variant has a role in recessive COL6A2 C-globular missense mutations in Ullrich congenital muscular dystrophy

  10. The alpha2(VI) chain modulates matrix-metalloproteinase (show MMP20 Antibodies) (MMP) availability by sequestering proMMPs in the extracellular matrix, blocking proteolytic activity.

Mouse (Murine) Collagen, Type VI, alpha 2 (COL6A2) interaction partners

  1. gamma-sarcoglycan (show SGCG Antibodies)-null/Col6a2Deltaex5 (Col6a2 deficient) mice exhibit reduced muscle pathology compared with gamma-sarcoglycan (show SGCG Antibodies)-null mice. Specifically, fewer muscle fibers are degenerating, fiber size varies less. Surprisingly, in spite of this reduction in muscle pathology, muscle function is not significantly improved.

Collagen, Type VI, alpha 2 (COL6A2) Antigen Profile

Protein Summary

This gene encodes one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. The product of this gene contains several domains similar to von Willebrand Factor type A domains. These domains have been shown to bind extracellular matrix proteins, an interaction that explains the importance of this collagen in organizing matrix components. Mutations in this gene are associated with Bethlem myopathy and Ullrich scleroatonic muscular dystrophy. Three transcript variants have been identified for this gene.

Gene names and symbols associated with COL6A2

  • collagen, type VI, alpha 2 (COL6A2) antibody
  • collagen, type VI, alpha 2 (col6a2) antibody
  • collagen, type VI, alpha 2 (LOC100224039) antibody
  • collagen, type VI, alpha 2 (Tcur_3411) antibody
  • collagen, type VI, alpha 2 (Col6a2) antibody
  • Col6a-2 antibody
  • PP3610 antibody

Protein level used designations for COL6A2

collagen alpha-2(VI) chain , alpha 2 type VI collagen , collagen, type VI, alpha 2 , collagen VI, alpha-2 polypeptide , human mRNA for collagen VI alpha-2 C-terminal globular domain , collagen type VI alpha 2 , procollagen, type VI, alpha 2 , type VI collagen alpha-2 subunit

GENE ID SPECIES
282194 Bos taurus
474056 Pan troglodytes
567771 Danio rerio
709493 Macaca mulatta
100224039 Taeniopygia guttata
8604757 Thermomonospora curvata DSM 43183
100055332 Equus caballus
100602701 Nomascus leucogenys
1292 Homo sapiens
100101552 Sus scrofa
12834 Mus musculus
361821 Rattus norvegicus
396292 Gallus gallus
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