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anti-Collagen, Type VII, alpha 1 (COL7A1) Antibodies

COL7A1 encodes the alpha chain of type VII collagen. Additionally we are shipping COL7A1 Kits (12) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
COL7A1 1294 Q02388
COL7A1 12836 Q63870
COL7A1    
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Top anti-COL7A1 Antibodies at antibodies-online.com

Showing 8 out of 8 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF, IHC, ELISA 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Rabbit Un-conjugated ELISA, IF, IHC   100 μL Log in to see 14 Days
$201.19
Details
Human Rabbit Un-conjugated ICC, IHC (p), ELISA   50 μg Log in to see 11 to 13 Days
$478.80
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry of Human thyroid cancer using COL7A1 Polyclonal Antibody at dilution of 1:25 200 μL Log in to see 8 to 9 Days
$588.50
Details
Cow Goat Un-conjugated WB 0.1 mg Log in to see 6 Days
$412.86
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 9 Days
$588.50
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 11 to 16 Days
$639.57
Details
Human Rabbit Un-conjugated IC, IHC, ELISA, WB   100 μg Log in to see 11 to 16 Days
$567.29
Details

COL7A1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , ,
,

Mouse (Murine) ,


Rat (Rattus) ,
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More Antibodies against COL7A1 Interaction Partners

Cow (Bovine) Collagen, Type VII, alpha 1 (COL7A1) interaction partners

  1. The identified mutation causes a premature stop codon which leads to a truncated protein representing a complete loss of COL7A1 function (p.R1586*). We thus have identified a candidate causative

Human Collagen, Type VII, alpha 1 (COL7A1) interaction partners

  1. TANGO1 (show MIA3 Antibodies) is thus pivotal in concentrating procollagen VII (show TH Antibodies) in the lumen and recruiting ERGIC membranes on the cytoplasmic surface of the endoplasmic reticulum.

  2. Novel dystrophic epidermolysis bullosa COL7a1 framshift mutation c.5493delG (p.K1831Nfs*10) in exon 64 leads to a premature termination codon located 10 amino acids downstream in exon 64 (p.K1831Nfs*10) and is expected to result in a loss of function.

  3. In conclusion, we identified a Japanese founder recurrent mutation of c.6216 + 5G > T, inducing aberrant splicing of COL7A1 and tending to cause a mild phenotype of recessive dystrophic epidermolysis bullosa

  4. COL7A1 mutations have a role in Recessive Dystrophic Epidermolysis Bullosa and can be corrected meganuclease-mediated homology-directed repair

  5. Type VII (show TH Antibodies) collagen suppresses TGFbeta (show TGFB1 Antibodies) signaling and angiogenesis in cutaneous SCC (show CYP11A1 Antibodies) (squamous cell carcinoma). Patients with recessive dystrophic epidermolysis bullosa (RDEB) SCC (show CYP11A1 Antibodies) may benefit from anti-angiogenic therapy.

  6. COL7A1 mutation was diagnosed with next generation sequencing in patient with dystrophic epidermolysis bullosa.

  7. Collagen Type VII (show TH Antibodies) missense mutation is responsible for the development of recessive bullous epidermolysis.

  8. A novel dominantnegative heterozygous acceptor splice site mutation in the COL7A1 gene (IVS671G>T) was found in both our patient and his youngest son.

  9. Results suggest that In children with a moderate form of DEB (show SNRPF Antibodies) with no or moderate skin fragility, a glycine substitution near the THD interruption domain of the collagen VII (show TH Antibodies) leading to thermolabile protein could explain this phenomenon

  10. anti-type VII (show TH Antibodies) collagen autoantibodies fluctuated in parallel with disease activity in epidermolysis bullosa acquisita

Mouse (Murine) Collagen, Type VII, alpha 1 (COL7A1) interaction partners

  1. The cystine knot (show KCNK7 Antibodies) is N-terminal to the collagen triple helix in in collagen type VII (show TH Antibodies) and IX and therefore probably impedes unfolding of the collagen triple helix from the N terminus.

  2. COL7A1 is required for re-epithelialization through organization of laminin-332 at the dermal-epidermal junction during wound healing.

  3. Tissue-bound, but not circulating, complement-fixing COL7-specific autoantibodies are associated with T helper type (Th)1 (show TH1L Antibodies) cell type cytokine expression and response in mice seusceptible to epidermolysis bullosa acquisita.

  4. An interaction of mvWFA2 with its neighboring domain mFNIII-9 was characterized with NMR spectroscopy and SPR (show SPR Antibodies)

  5. transforming growth factor beta1 stimulation of Col7a1 transcription is dependent on a putative interaction between Smads and AP1 (show JUN Antibodies).

  6. single amino acid substitutions in procollagen VII (show TH Antibodies) alter its self-assembly

  7. All mice developed circulating IgG autoantibodies that recognized type VII (show TH Antibodies) collagen and bound to the lamina densa of the dermal-epidermal junction[type VII (show TH Antibodies) collagen]

  8. Results describe the generation of a collagen VII (show TH Antibodies) alpha 1 hypomorphic mouse that serves as an immunocompetent animal model for dystrophic epidermolysis bullosa.

COL7A1 Antigen Profile

Protein Summary

This gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen.

Gene names and symbols associated with COL7A1

  • collagen, type VII, alpha 1 (COL7A1) antibody
  • collagen, type VII, alpha 1 (col7a1) antibody
  • collagen, type VII, alpha 1 (Col7a1) antibody
  • AW209154 antibody
  • COL7A1 antibody
  • EBD1 antibody
  • EBDCT antibody
  • EBR1 antibody

Protein level used designations for COL7A1

collagen alpha-1(VII) chain , collagen, type VII, alpha 1 (epidermolysis bullosa, dystrophic, dominant and recessive) , collagen, type VII, alpha 1 , alpha 1 type VII collagen , collagen alpha-1(VII) chain-like , LC collagen , collagen VII, alpha-1 polypeptide , long-chain collagen , procollagen, type VII, alpha 1

GENE ID SPECIES
403467 Canis lupus familiaris
460347 Pan troglodytes
507133 Bos taurus
709354 Macaca mulatta
100454508 Pongo abelii
100489404 Xenopus (Silurana) tropicalis
100523209 Sus scrofa
1294 Homo sapiens
12836 Mus musculus
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