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Collagen, Type VII, alpha 1 (COL7A1) ELISA Kits

COL7A1 encodes the alpha chain of type VII collagen. Additionally we are shipping COL7A1 Antibodies (8) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
COL7A1 1294 Q02388
COL7A1 12836 Q63870
COL7A1    
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Top COL7A1 ELISA Kits at antibodies-online.com

Showing 7 out of 12 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 0.078 ng/ml 0.312-20 ng/mL 96 Tests Log in to see 11 to 13 Days
$910.56
Details
Mouse 0.039 ng/ml 0.156-10 ng/mL 96 Tests Log in to see 11 to 13 Days
$910.56
Details
Guinea Pig
96 Tests Log in to see 16 to 21 Days
$999.43
Details
Rat
96 Tests Log in to see 16 to 21 Days
$999.43
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Dog
96 Tests Log in to see 16 to 21 Days
$999.43
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Rabbit
96 Tests Log in to see 16 to 21 Days
$999.43
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Monkey
96 Tests Log in to see 16 to 21 Days
$999.43
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More ELISA Kits for COL7A1 Interaction Partners

Cow (Bovine) Collagen, Type VII, alpha 1 (COL7A1) interaction partners

  1. The identified mutation causes a premature stop codon which leads to a truncated protein representing a complete loss of COL7A1 function (p.R1586*). We thus have identified a candidate causative

Human Collagen, Type VII, alpha 1 (COL7A1) interaction partners

  1. TANGO1 (show MIA3 ELISA Kits) is thus pivotal in concentrating procollagen VII (show TH ELISA Kits) in the lumen and recruiting ERGIC membranes on the cytoplasmic surface of the endoplasmic reticulum.

  2. Novel dystrophic epidermolysis bullosa COL7a1 framshift mutation c.5493delG (p.K1831Nfs*10) in exon 64 leads to a premature termination codon located 10 amino acids downstream in exon 64 (p.K1831Nfs*10) and is expected to result in a loss of function.

  3. In conclusion, we identified a Japanese founder recurrent mutation of c.6216 + 5G > T, inducing aberrant splicing of COL7A1 and tending to cause a mild phenotype of recessive dystrophic epidermolysis bullosa

  4. COL7A1 mutations have a role in Recessive Dystrophic Epidermolysis Bullosa and can be corrected meganuclease-mediated homology-directed repair

  5. Type VII (show TH ELISA Kits) collagen suppresses TGFbeta (show TGFB1 ELISA Kits) signaling and angiogenesis in cutaneous SCC (show CYP11A1 ELISA Kits) (squamous cell carcinoma). Patients with recessive dystrophic epidermolysis bullosa (RDEB) SCC (show CYP11A1 ELISA Kits) may benefit from anti-angiogenic therapy.

  6. COL7A1 mutation was diagnosed with next generation sequencing in patient with dystrophic epidermolysis bullosa.

  7. Collagen Type VII (show TH ELISA Kits) missense mutation is responsible for the development of recessive bullous epidermolysis.

  8. A novel dominantnegative heterozygous acceptor splice site mutation in the COL7A1 gene (IVS671G>T) was found in both our patient and his youngest son.

  9. Results suggest that In children with a moderate form of DEB (show SNRPF ELISA Kits) with no or moderate skin fragility, a glycine substitution near the THD interruption domain of the collagen VII (show TH ELISA Kits) leading to thermolabile protein could explain this phenomenon

  10. anti-type VII (show TH ELISA Kits) collagen autoantibodies fluctuated in parallel with disease activity in epidermolysis bullosa acquisita

Mouse (Murine) Collagen, Type VII, alpha 1 (COL7A1) interaction partners

  1. The cystine knot (show KCNK7 ELISA Kits) is N-terminal to the collagen triple helix in in collagen type VII (show TH ELISA Kits) and IX and therefore probably impedes unfolding of the collagen triple helix from the N terminus.

  2. COL7A1 is required for re-epithelialization through organization of laminin-332 at the dermal-epidermal junction during wound healing.

  3. Tissue-bound, but not circulating, complement-fixing COL7-specific autoantibodies are associated with T helper type (Th)1 (show TH1L ELISA Kits) cell type cytokine expression and response in mice seusceptible to epidermolysis bullosa acquisita.

  4. An interaction of mvWFA2 with its neighboring domain mFNIII-9 was characterized with NMR spectroscopy and SPR (show SPR ELISA Kits)

  5. transforming growth factor beta1 stimulation of Col7a1 transcription is dependent on a putative interaction between Smads and AP1 (show JUN ELISA Kits).

  6. single amino acid substitutions in procollagen VII (show TH ELISA Kits) alter its self-assembly

  7. All mice developed circulating IgG autoantibodies that recognized type VII (show TH ELISA Kits) collagen and bound to the lamina densa of the dermal-epidermal junction[type VII (show TH ELISA Kits) collagen]

  8. Results describe the generation of a collagen VII (show TH ELISA Kits) alpha 1 hypomorphic mouse that serves as an immunocompetent animal model for dystrophic epidermolysis bullosa.

COL7A1 Antigen Profile

Antigen Summary

This gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen.

Gene names and symbols associated with COL7A1

  • collagen, type VII, alpha 1 (COL7A1) antibody
  • collagen, type VII, alpha 1 (col7a1) antibody
  • collagen, type VII, alpha 1 (Col7a1) antibody
  • AW209154 antibody
  • COL7A1 antibody
  • EBD1 antibody
  • EBDCT antibody
  • EBR1 antibody

Protein level used designations for COL7A1

collagen alpha-1(VII) chain , collagen, type VII, alpha 1 (epidermolysis bullosa, dystrophic, dominant and recessive) , collagen, type VII, alpha 1 , alpha 1 type VII collagen , collagen alpha-1(VII) chain-like , LC collagen , collagen VII, alpha-1 polypeptide , long-chain collagen , procollagen, type VII, alpha 1

GENE ID SPECIES
403467 Canis lupus familiaris
460347 Pan troglodytes
507133 Bos taurus
709354 Macaca mulatta
100454508 Pongo abelii
100489404 Xenopus (Silurana) tropicalis
100523209 Sus scrofa
1294 Homo sapiens
12836 Mus musculus
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