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anti-Collagen, Type VIII, alpha 1 (COL8A1) Antibodies

COL8A1 encodes one of the two alpha chains of type VIII collagen. Additionally we are shipping COL8A1 Kits (32) and COL8A1 Proteins (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
COL8A1 12837 Q00780
COL8A1 304021  
COL8A1 1295 P27658
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Top anti-COL8A1 Antibodies at antibodies-online.com

Showing 10 out of 37 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB COL8A1 Antibody (N-term)  western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the COL8A1 antibody detected the COL8A1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 8 to 10 Days
$478.50
Details
Rabbit Guinea Pig Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$418.00
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Rabbit Mouse Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$308.00
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$385.00
Details
Human Rabbit PE ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated IHC   0.1 mg Log in to see 5 to 7 Days
$385.00
Details
Mouse Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 11 to 13 Days
$396.00
Details
Rat Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 11 to 13 Days
$418.00
Details

COL8A1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,



Rat (Rattus)



Human ,
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Top referenced anti-COL8A1 Antibodies

  1. Human Polyclonal COL8A1 Primary Antibody for IHC - ABIN965914 : Muragaki, Mattei, Yamaguchi, Olsen, Ninomiya: The complete primary structure of the human alpha 1 (VIII) chain and assignment of its gene (COL8A1) to chromosome 3. in European journal of biochemistry / FEBS 1991 (PubMed)
    Show all 9 references for ABIN965914

More Antibodies against COL8A1 Interaction Partners

Mouse (Murine) Collagen, Type VIII, alpha 1 (COL8A1) interaction partners

  1. Lack of collagen VIII (show COX8A Antibodies) reduces myofibroblast differentiation and fibrosis and promotes early mortality and left ventricle dilatation in response to pressure overload in mice.

  2. Type VIII (show COX8A Antibodies) collagen signals via beta1 integrin and RhoA (show RHOA Antibodies) to regulate MMP-2 (show MMP2 Antibodies) expression and smooth muscle cell migration.

  3. Type VIII (show COX8A Antibodies) collagen mediates vessel wall remodeling after arterial injury and fibrous cap formation in atherosclerosis.

  4. in contrast to diabetic wild-type mice EMT (show ITK Antibodies)-like changes were attenuated in diabetic Col8alpha1/alpha2-KO mice, indicating that collagen VIII (show COX8A Antibodies) may be 1 of the major inducers of epithelial-to-mesenchymal transition-like changes in kidneys of diabetic wild-type mice

  5. Type VIII (show COX8A Antibodies) collagen significantly modulates the effect of TGF-beta1 (show TGFB1 Antibodies) on mesangial cells and may therefore play a role in the pathogenesis of diabetic nephropathy.

  6. Crystal structure of mouse alpha1(VIII (show COX8A Antibodies))(3) NC1 domain trimer at 1.9 A resolution. Surface of collagen VIII (show COX8A Antibodies) NC1 trimer has three strips of partially exposed aromatic residues, likely involved in supramolecular assemblies.

  7. These data indicate that type VIII (show COX8A Antibodies) collagen plays an important role in glial scar formation during the repair process by astrocytes.

  8. Smooth muscle cells can modify the matrix microenvironment by producing type VIII (show COX8A Antibodies) collagen, using it to overlay type I collagen, and generating a substrate favorable for migration

  9. Downregulation of COL8A1 expression sensitized hepatocarcinoma cells to the action of D-limonene, impeded cell proliferation, and led to decreased invasiveness, indicating that COL8A1 might serve as a target for gene therapy in hepatocarcinoma.

  10. Oxidized phospholipids induce type VIII (show COX8A Antibodies) collagen expression and vascular smooth muscle cell migration.

Human Collagen, Type VIII, alpha 1 (COL8A1) interaction partners

  1. High COL8A1 expression is associated with early loss of kidney function.

  2. Data indicate that complement factor H (CFH (show CFH Antibodies)) R1210C and common variants in COL8A1 and RAD51B (show Rad51B Antibodies) plus six genes contribute predictive information for advanced macular degeneration (AMD (show AMD1 Antibodies)) beyond macular and behavioral phenotypes.

  3. The results are consistent with the proposal that rare CNVs play a role in TS aetiology and suggest a possible role for rearrangements in the COL8A1 and NRXN1 (show NRXN1 Antibodies) gene regions.

  4. In addition, eight genes classified as 'second tier' hits in the original study (PAX7 (show PAX7 Antibodies), THADA, COL8A1/FILIP1L (show FILIP1L Antibodies), DCAF4L2, GADD45G (show GADD45G Antibodies), NTN1 (show NTN1 Antibodies), RBFOX3 (show RBFOX3 Antibodies) and FOXE1 (show FOXE1 Antibodies)) showed evidence of linkage and association in this replication sample.

  5. The purpose of this study is to evaluate COL8A1 and COL8A2 (show COL8a2 Antibodies) as candidate genes for thin central corneal thickness in human primary open angle glaucoma patients.

  6. The absence of pathogenic mutations identified in the COL8A1 or COL8A2 (show COL8a2 Antibodies) genes in affected members of 15 pedigrees with familial FECD (show COL8a2 Antibodies) (Fuchs endothelial corneal dystrophy) indicates that other genetic factors are involved.

  7. The absence of pathogenic mutations in COL8A1 and COL8A2 (show COL8a2 Antibodies) in patients with keratoconus indicates that other genetic factors are involved in the pathogenesis of this corneal ectatic disorder.

COL8A1 Antigen Profile

Protein Summary

This gene encodes one of the two alpha chains of type VIII collagen. The gene product is a short chain collagen and a major component of the basement membrane of the corneal endothelium. The type VIII collagen fibril can be either a homo- or a heterotrimer. Alternatively spliced transcript variants encoding the same protein have been observed.

Gene names and symbols associated with COL8A1

  • collagen, type VIII, alpha 1 (COL8A1) antibody
  • collagen, type VIII, alpha 1 (col8a1) antibody
  • collagen, type VIII, alpha 1 (Col8a1) antibody
  • C3orf7 antibody
  • Col8a-1 antibody
  • COL8A1 antibody

Protein level used designations for COL8A1

collagen, type VIII, alpha 1 , collagen alpha-1(VIII) chain , procollagen type VIII alpha 1 , procollagen, type VIII, alpha 1 , cell proliferation-inducing protein 41 , collagen VIII, alpha-1 polypeptide , endothelial collagen , smooth muscle cell-expressed and macrophage conditioned medium-induced protein smag-64 , alpha 1 type VIII collagen , collagen VIII , type VIII collagen alpha 1 chain

GENE ID SPECIES
460550 Pan troglodytes
494652 Xenopus laevis
100017530 Monodelphis domestica
100585226 Nomascus leucogenys
12837 Mus musculus
304021 Rattus norvegicus
1295 Homo sapiens
100009383 Oryctolagus cuniculus
100717829 Cavia porcellus
397430 Sus scrofa
418378 Gallus gallus
487950 Canis lupus familiaris
538564 Bos taurus
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