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anti-Collagen, Type X, alpha 1 (COL10A1) Antibodies

COL10A1 encodes the alpha chain of type X collagen, a short chain collagen expressed by hypertrophic chondrocytes during endochondral ossification. Additionally we are shipping Collagen, Type X, alpha 1 Kits (22) and Collagen, Type X, alpha 1 Proteins (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
COL10A1 1300 Q03692
Anti-Mouse COL10A1 COL10A1 12813 Q05306
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Top anti-Collagen, Type X, alpha 1 Antibodies at antibodies-online.com

Showing 10 out of 20 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB COL10A1 Antibody (N-term) (ABIN1881220) western blot analysis in K562 cell line lysates (35 µg/lane). This demonstrates the COL10A1 antibody detected the COL10A1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit PE ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Un-conjugated IHC   50 μL Log in to see 8 to 10 Days
$390.50
Details
Human Rabbit Un-conjugated ELISA, WB   200 μL Log in to see 11 to 16 Days
$532.71
Details
Human Rabbit HRP ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit FITC ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit APC ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit PE ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details

COL10A1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Collagen, Type X, alpha 1 Antibodies

  1. Human Polyclonal COL10A1 Primary Antibody for WB - ABIN1881220 : Mäkitie, Susic, Cole: Early-onset metaphyseal chondrodysplasia type Schmid associated with a COL10A1 frame-shift mutation and impaired trimerization of wild-type α1(X) protein chains. in Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2010 (PubMed)
    Show all 5 references for ABIN1881220

More Antibodies against Collagen, Type X, alpha 1 Interaction Partners

Human Collagen, Type X, alpha 1 (COL10A1) interaction partners

  1. a novel sequence variation involving an unusual mutational site of the COL10A1 gene can cause mild metaphyseal chondrodysplasia (show COL11A1 Antibodies)

  2. COL10A1 mutation 2005delC in a Chinese pedigree with Schmid type metaphyseal chondrodysplasia (show COL11A1 Antibodies) is close to the C-terminus of the protein sequence and may result in genetic heterogeneity of the Chinese population

  3. The results show that COL10A1 is a tumor biomarker upregulated in a wide variety of tumors including those of the breast, colon, bladder, stomach, esophagus, lung, testis, ovary and pancreas.

  4. Yiqi Huayu Bushen Recipe increased the expression of aggrecan (show ACAN Antibodies), decreased the expression of type X collagen, and promoted cell proliferation in cells from degenerated human intervertebral discs.

  5. Genetic variation near FRK (show FRK Antibodies)/COL10A1 and VEGFA (show VEGFA Antibodies) are associated with advanced age-related macular degeneration.

  6. MCDS is a rare genetic skeletal disorder caused by a collagen type X defect. Though much is known about the molecular pathology of the causative COL10A1 mutations, causal therapy of the disease is not yet available

  7. a frameshift mutation leading to elongation of the deduced alpha1(X) chain associated with Metaphyseal Chondrodysplasia (show COL11A1 Antibodies) type Schmid

  8. The effect of parathyroid hormone on expression of COL10 and COL2 in mesenchymal stem cells from osteoarthritic patients and analyzed the potential mechanisms related to its effect, was investigated.

  9. These results indicate that nitrogen-rich plasma polymerized surfaces inhibit COL10A1 expression via the suppression of COX-1 (show COX1 Antibodies).

  10. speculate that complete loss of mutant transcripts yields COL10A1 haploinsufficiency and late clinical presentation while incomplete loss of mutant transcripts yields dominant-negative effects with early clinical presentation

Mouse (Murine) Collagen, Type X, alpha 1 (COL10A1) interaction partners

  1. Col10 expression was seen in the hypertrophic zone at and below the tidemark of the mandibular condyle cartilage.

  2. These data support a Cox-2 (show COX2 Antibodies)-containing, Runx2 (show RUNX2 Antibodies)-centered Col10a1 regulatory mechanism, during chondrocyte hypertrophic differentiation.

  3. Data indicate Indian hedgehog (Ihh (show IHH Antibodies)) induces collagen type X COL10A1 expression and promotes its transcription through Runx2 (show RUNX2 Antibodies)/Smad1 (show SMAD1 Antibodies) interactions on a specific promoter region.

  4. these results show that increased Col10a1 expression in Phex (show PHEX Antibodies)-deficient osteoblasts is not a major cause of the XLHR phenotype, which was an important issue to address based on the previous findings

  5. Downregulation of carbonic anhydrase IX (show CA9 Antibodies) promotes Col10a1 expression in chondrocytes.

  6. Runx2 (show RUNX2 Antibodies) directly interacts with murine Col10a1 cis (show CISH Antibodies)-enhancer.

  7. SOX9 (show SOX9 Antibodies) directly represses Col10a1 expression in immature/proliferating chondrocytes of the growth plate

  8. Studies indicate that Col10a1 is highly expressed in hypertrophic chondrocytes and commonly used as a gene marker for this cell population.

  9. cartilaginous regeneration is due to the expression of chondrogenic factors, such as Sox 9 (show SOX9 Antibodies) and type II and X collagens

  10. we have uncovered a novel molecular mechanism linking GADD45beta (show GADD45B Antibodies) via the MTK1 (show MAP3K4 Antibodies)/MKK3 (show MAP2K3 Antibodies)/6/p38 (show CRK Antibodies) axis to C/EBPbeta (show CEBPB Antibodies)-TAD4 activation of Col10a1 transcription in terminally differentiating chondrocytes

Cow (Bovine) Collagen, Type X, alpha 1 (COL10A1) interaction partners

  1. The 4.6 kb promoter is able to drive specific expression of Col10a1 in hypertrophic cartilage.

  2. TSG is an important modulator of BMP-regulated induced collagen II and X expression and cartilage development and chondrocyte differentiation

Collagen, Type X, alpha 1 (COL10A1) Antigen Profile

Protein Summary

This gene encodes the alpha chain of type X collagen, a short chain collagen expressed by hypertrophic chondrocytes during endochondral ossification. Unlike type VIII collagen, the other short chain collagen, type X collagen is a homotrimer. Mutations in this gene are associated with Schmid type metaphyseal chondrodysplasia (SMCD) and Japanese type spondylometaphyseal dysplasia (SMD).

Gene names and symbols associated with COL10A1

  • collagen alpha-1(X) chain-like (LOC100858979) antibody
  • collagen, type X, alpha 1 (COL10A1) antibody
  • collagen, type X, alpha 1 (Col10a1) antibody
  • Col10 antibody
  • Col10a-1 antibody

Protein level used designations for COL10A1

Schmid metaphyseal chondrodysplasia , collagen X, alpha-1 polypeptide , collagen alpha-1(X) chain , procollagen, type X, alpha 1 , collagen, type X, alpha 1 (Schmid metaphyseal chondrodysplasia) , collagen, type X, alpha 1(Schmid metaphyseal chondrodysplasia) , type X collagen alpha 1

GENE ID SPECIES
100858979 Gallus gallus
1300 Homo sapiens
12813 Mus musculus
282416 Bos taurus
100126150 Gallus gallus
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