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anti-Collagen, Type XVII, alpha 1 (COL17A1) Antibodies

COL17A1 encodes the alpha chain of type XVII collagen. Additionally we are shipping COL17A1 Kits (18) and COL17A1 Proteins (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
Anti-Rat COL17A1 COL17A1 294027  
COL17A1 1308 Q9UMD9
COL17A1 12821 Q07563
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Top anti-COL17A1 Antibodies at antibodies-online.com

Showing 10 out of 37 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of COL17A1 Antibody (Center) (ABIN653043) in A375, A2058, HL-60, MCF-7 cell line lysates (35 µg/lane). COL17A1 (arrow) was detected using the purified polyclonal antibody. COL17A1 Antibody (Center) (ABIN653043) IHC analysis in formalin fixed and paraffin embedded skin tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit PE FACS, IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated ELISA, IHC 100 μL Log in to see 14 Days
$201.19
Details
Mouse Rabbit Un-conjugated IHC   10 μg Log in to see 8 to 10 Days
$610.50
Details
Human Rabbit FITC WB   100 μg Log in to see 8 to 10 Days
$683.83
Details
Human Rabbit Un-conjugated FACS, ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Un-conjugated IHC, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated ELISA   100 μg Log in to see 8 to 10 Days
$537.17
Details
Human Mouse Un-conjugated ELISA, WB   10 μg Log in to see 8 to 10 Days
$610.50
Details
Human Rabbit Un-conjugated FACS, IHC, ELISA, WB   200 μL Log in to see 11 to 16 Days
$532.71
Details

COL17A1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Mouse (Murine)


More Antibodies against COL17A1 Interaction Partners

Human Collagen, Type XVII, alpha 1 (COL17A1) interaction partners

  1. R1303Q in COL17 hampers C-terminal cleavage of COL17. Increase in remnants of non-cleaved COL17 ectodomain in extracellular matrix (ECM (show MMRN1 Antibodies)) induces aberrant laminin 332 deposition in ECM (show MMRN1 Antibodies), which may be associated with disorganized basement membrane formation.

  2. The COL17A1 c.3156C-->T variant is the likely causative mutation in our recurrent corneal erosion families, and its presence in 4 independent families suggests that it is prevalent in epithelial recurrent erosion dystrophy.

  3. Elevated serum levels of BP180 antibodies in the first trimester of pregnancy precede gestational pemphigoid and remain elevated for a long time after remission of the disease.

  4. Letter/Case Report: IgE BP180 antibodies contribute to the occurrence of urticarial erythema in bullous pemphigoid (show DST Antibodies) patients.

  5. IgE anti-BP180 autoantibody level is increased in some Chinese patients with bullous pemphigoid (show DST Antibodies).

  6. The aging process can be recapitulated by Col17a1 deficiency and prevented by the forced maintenance of COL17A1 in hair follicle stem cell (HFSCs), demonstrating that COL17A1 in HFSCs orchestrates the stem cell-centric aging program of the epithelial mini-organ.

  7. Our findings implicate presumed gain-of-function COL17A1 mutations causing dominantly inherited ERED and improve understanding of the underlying pathology.

  8. Case Reports: two Japanese patients with bullous pemphigoid (show DST Antibodies) with only BP230 (show DST Antibodies) autoantibodies detected by ELISA.

  9. Circulating anti-BP180 autoantibodies are not correlated with severity of genital lichen sclerosis or itching.

  10. Variants of the PTCH1 (show PTCH1 Antibodies) and COL17A1 genes may contribute to the development of Ossification of the posterior longitudinal ligament.

Mouse (Murine) Collagen, Type XVII, alpha 1 (COL17A1) interaction partners

  1. The aging process can be recapitulated by Col17a1 deficiency and prevented by the forced maintenance of COL17A1 in hair follicle stem cell (HFSCs), demonstrating that COL17A1 in HFSCs orchestrates the stem cell-centric aging program of the epithelial mini-organ.

  2. The deletion of the bullous pemphigoid (show DST Antibodies) epitope region of collagen XVII induces blistering, autoimmunization, and itching in a mouse disease model.

  3. Through an unbiased genetic approach involving a combination of QTL mapping and positional cloning, we demonstrate that Col17a1 is a strong genetic modifier of the non-Herlitz JEB that develops in Lamc2 (show LAMC2 Antibodies)(jeb) mice

  4. These results provide mechanistic evidence that ColXVII coordinates keratinocyte adhesion and directed motility by interfering integrin dependent PI3K activation and by stabilizing lamellipodia

  5. Neutrophil elastase (show ELANE Antibodies) cleaves the murine hemidesmosomal protein BP180/type XVII collagen and generates degradation products that modulate experimental bullous pemphigoid (show DST Antibodies)

  6. Analysis of Col17a1-null mice revealed that COL17A1 is critical for the self-renewal of hair follicle stem cells through maintaining their quiescence and immaturity.

  7. bullous pemphigoid antigen 2 has a role in eliciting specific IgG and the immune responses arising in epidermolysis bullosa

  8. ADAM9 (show ADAM9 Antibodies) and ADAM10 (show ADAM10 Antibodies) can both contribute to collagen XVII shedding in skin.

Cow (Bovine) Collagen, Type XVII, alpha 1 (COL17A1) interaction partners

  1. results show that the cleavage of BP180 occurring within the NC16A domain is mediated by a membrane-associated metalloprotease (show ADAM8 Antibodies) and suggest involvement of the cleavage in hemidesmosomal disassembly(bullous pemphigoid antigen 180/type XVII collagen)

COL17A1 Antigen Profile

Protein Summary

This gene encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form.

Gene names and symbols associated with COL17A1

  • collagen, type XVII, alpha 1 (Col17a1) antibody
  • collagen, type XVII, alpha 1b (col17a1b) antibody
  • collagen, type XVII, alpha 1 (COL17A1) antibody
  • BA16H23.2 antibody
  • BP180 antibody
  • BPA-2 antibody
  • Bpag antibody
  • Bpag2 antibody
  • COL17A1 antibody
  • fk89a06 antibody
  • LAD-1 antibody
  • si:ch211-223p8.6 antibody
  • wu:fk89a06 antibody

Protein level used designations for COL17A1

collagen alpha-1(XVII) chain , procollagen, type XVII, alpha 1 , col17a1a , collagen, type XVII, alpha 1 , collagen alpha-1(XVII) chain-like , 180 kDa bullous pemphigoid antigen 2 , alpha 1 type XVII collagen , bA16H23.2 (collagen, type XVII, alpha 1 (BP180)) , bullous pemphigoid antigen 2 (180kD) , collagen XVII, alpha-1 polypeptide , bullous pemphigoid antigen 2 , bullous pemphigoid antigen 180 , novel collagen protein , Collagen alpha-1(XVII) chain , bullous pemphigoid autoantigen 2 , Bullous pemphigoid antigen 2 , collagen type XVII

GENE ID SPECIES
294027 Rattus norvegicus
568794 Danio rerio
100452122 Pongo abelii
100069671 Equus caballus
100604365 Nomascus leucogenys
1308 Homo sapiens
12821 Mus musculus
513804 Bos taurus
396503 Gallus gallus
403739 Canis lupus familiaris
101843802 Mesocricetus auratus
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